Tennessee Clinical Trials

A listing of Tennessee clinical trials actively recruiting patient volunteers.

Tennessee is a lively and lovely state known as the birthplace of bluegrass and the site of Graceland and Dollywood. It's also the place to go to see one of America's most iconic national parks, The Great Smoky Mountain National Park. Nashville is where you can immerse yourself in the history of the music business, while Memphis, Knoxville, and Gatlinburg each offer their own perks and sights. In any of these cities and beyond, sound healthcare is easy to find. Vanderbilt University Medical Center has been ranked #1 in the state, with more than 1,000 acute care beds in service.

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2204 trials found

An Observational Registry of Abatacept in Patients With Juvenile Idiopathic Arthritis

NCT01357668

The purpose of this study is to examine the long-term safety of Abatacept for the treatment of juvenile idiopathic arthritis (JIA) with particular in interest in the occurrence of serious infections, autoimmune disorders, and malignancies.

Conditions: Juvenile Idiopathic Arthritis

Nashville Early Diagnosis Lung Cancer Project

NCT01475500

This screening study will address the lack of molecular strategies for the early detection of lung cancer and integrate those with epidemiological and imaging strategies. The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens including those from bronchoscopy (bronchial brushings and biopsies) may contribute to the refinement of high-risk populations and allow an earlier clinical diagnosis. The goal of the investigators st ...

Conditions: Lung Cancer

Caris Biorepository Research Protocol

NCT01499394

The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens ...

Conditions: Cancer

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

NCT01503086

This randomized clinical trial studies how well an adaptive computerized cognitive training program works compared to a non-adaptive computerized cognitive training program in treating younger patients with brain tumor who underwent radiation therapy. Providing a computer training program may improve the well-being and quality of life of patients with cognitive (physical and mental) function difficulties caused by radiation therapy to the brain.

Conditions: Brain Neoplasm, Recurrent Brain Neoplasm
Phase: Not Applicable

Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants

NCT01512888

SCID-X1 is a genetic disorder of blood cells caused by DNA changes in a gene that is required for the normal development of the human immune system. The purpose of this study is to determine if a new method, called lentiviral gene transfer, can be used to treat SCID-X1. This method involves transferring a normal copy of the common gamma chain gene into the participant's bone marrow stem cells. The investigators want to determine if the procedure is safe, whether it can be done according to the m ...

Conditions: Severe Combined Immunodeficiency Disease, X-linked
Phase: Phase 1/2

Product Surveillance Registry

NCT01524276

The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies, payers, and industry by streamlining the clinical surveillance process and facilitating leading edge performance assessment via the least burdensome approach.

Conditions: Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders, Digestive Disorders, Intracranial Aneurysm, Mechanical Circulatory Support, Respiratory Therapy, Aortic, Peripheral Vascular and Venous Disorders, Minimally Invasive Surgical Procedures, Diagnostic Techniques and Procedures, Surgical Procedures, Operative, Renal Insufficiency, Neurovascular

Registry of AvanceĀ® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction

NCT01526681

This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.

Conditions: Peripheral Nerve Injuries

Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults

NCT01547429

This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.

Conditions: Aphakia
Phase: Not Applicable

Patient Retrospective Outcomes (PRO)

NCT01550575

This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.

Conditions: Chronic Pain

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

NCT01574053

Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 20,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b ...

Conditions: Huntington's Disease

Vorinostat in Treating Patients With Metastatic Melanoma of the Eye

NCT01587352

This phase II trial studies how well vorinostat works in treating patients with melanoma of the eye that has spread to other parts of the body (metastatic). Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Conditions: Stage IV Uveal Melanoma AJCC v7, Metastatic Uveal Melanoma

Proton Therapy vs. IMRT for Low or Intermediate Risk Prostate Cancer

NCT01617161

We are studying whether men being treated for prostate cancer have the same amount of side effects from either one of two different external radiation treatments: IMRT or PBT. With IMRT, a number of x-ray beams are used to shape the radiation to the prostate. PBT is another type of external radiation treatment for prostate cancer that is used in a few centers in the United States. Protons are tiny particles with positive charge that can be controlled to travel a certain distance and stop. PBT is ...

Conditions: Prostate Cancer
Phase: Not Applicable