Michigan is currently home to 2183 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Early Detection of Breast Cancer
Recruiting
The TriNetraâ„¢ Breast test is intended for use as a breast cancer screening test that evaluates Circulating Tumor Cells (CTCs) associated with breast cancer. The TriNetraâ„¢Breast test should be a useful breast cancer screening option for asymptomatic women 40 years of age and older. This pivotal study is designed to provide evidence of test performance and to demonstrate its safety in the intended use population in the USA.
Gender:
FEMALE
Ages:
40 years and above
Trial Updated:
09/18/2023
Locations: Rogel Cancer Center, Ann Arbor, Michigan
Conditions: Breast Neoplasms
A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination
Recruiting
This is a Phase 1/2, open-label, multicenter, dose escalation and expansion study, evaluating the safety, tolerability, pharmacokinetic, preliminary anti-tumor activity, and effects on pharmacodynamic markers following administration of SLC-3010 as monotherapy and in combination with gemcitabine, in patients with various advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: Selecxine Investigator site, Detroit, Michigan
Conditions: Advanced Solid Tumor
A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Recruiting
The primary objective of this study is to evaluate the effect of tolvaptan on the need for renal replacement therapy in pediatric subjects with autosomal recessive polycystic kidney disease (ARPKD)
Gender:
ALL
Ages:
Between 28 days and 12 weeks
Trial Updated:
09/14/2023
Locations: C.S. Mott Children's Hospital, Ann Arbor, Michigan
Conditions: Autosomal Recessive Polycystic Kidney Disease (ARPKD)
PK Study of Single-Dose ZTI-01 in Children (<12 Years of Age)
Recruiting
Phase 1 study, a single dose of ZTI-01 given to pediatric subjects (under 12 years of age) who require antibiotic therapy to see what the body does to the drug (pharmacokinetics) and to compare if these effects are similar to those observed in adults at a 6g ZTI-01 dose. Study will help establish pediatric dosing in younger children by age cohort. This is a multiple-center, open-label, PK study of ZTI-01 (fosfomycin for injection) single dose scaled by allometric weight-modeling from an adult ZT... Read More
Gender:
ALL
Ages:
11 years and below
Trial Updated:
09/14/2023
Locations: Children's Hospital of Michigan, Detroit, Michigan
Conditions: Pediatric ALL
A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
Recruiting
A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS G12C mutation to determine the maximum tolerated dose and recommended Phase II dose of HBI-2438 and characterize its pharmacokinetic profile.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: Michigan Center of Medical Research, Farmington Hills, Michigan
Conditions: Lung Cancer, Non Small Cell Lung Cancer, Colorectal Cancer, Cancer of Pancreas, Colon Cancer, Solid Tumor, Cancer
Symphony IL-6 Study in Patients at Risk of Severe Sepsis
Recruiting
Symphony IL-6 is a device that quantitates human IL-6 by fluorescence enzyme immunoassay (FEIA) from whole-blood specimens. Use of Symphony IL- 6 removes the need for plasma separation before testing. Symphony IL-6 comprises two components, the Symphony Fluorescence Immunoanalyzer and the Symphony IL-6 Cartridge. Whole blood is added to the cartridge and then up to six cartridges can be inserted into the immunoanalyzer. After 20 minutes a readout and printout are given with a quantitative IL-6 c... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
09/05/2023
Locations: University of Michigan Medical Center, Ann Arbor, Michigan
Conditions: Severe Sepsis
Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis
Recruiting
This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/05/2023
Locations: Henry Ford Health, Detroit, Michigan
Conditions: Osteomyelitis, Diabetic Foot Osteomyelitis
A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter Phase 3 study that will enroll approximately 368 subjects aged 18 to 75 years old with Moderately to Severely Active Ulcerative Colitis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/01/2023
Locations: Michigan Medical, Ann Arbor, Michigan
Conditions: Ulcerative Colitis
Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
Recruiting
Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/27/2023
Locations: Spectrum Health at Butterworth Campus, Grand Rapids, Michigan
Conditions: Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases
Total Shoulder Arthroplasty Multi-Center Registry
Recruiting
The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/27/2023
Locations: The University of Michigan, Ann Arbor, Michigan
Conditions: Shoulder Arthroplasty
Sustained Immunity to COVID-19 as Measured by SARS-CoV-2 Serology Assays
Recruiting
The primary objective is to assess the ability of COVID-19 IgG and IgM assays to detect an immune response in COVID-19 patients in the Henry Ford Health System (HFHS), both during hospitalization and over the following 12 months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Henry Ford Health System, Detroit, Michigan
Conditions: Covid19
Effects of Delta9-tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R33 Study
Recruiting
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these processes and how this relates to the treatment of post-traumatic stress disorder (PTSD). PTSD is an anxiety disorder that occurs after experiencing a traumatic event(s) and is characterized by unwanted memories of the trauma(s) through flashbacks or nightmares, avoidance... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/12/2023
Locations: Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, Michigan
Conditions: Posttraumatic Stress Disorder