There are currently 80 active clinical trials seeking participants for Diabetes research studies. The states with the highest number of trials for Diabetes participants are California, Texas, Florida and Pennsylvania.
A Natural History Study of Metabolic Sizing in Health and Disease
NCT05398783
Recruiting
Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metabolism varies among people with similar body sizes. Scientists now believe the old formulas for estimating metabolic rates may not work well for all people. Researchers want to find more accurate ways to measure a person s metabolism. Objective: This natural history study will examine the relations... Read More
Gender:
All
Ages:
Between 2 years and 99 years
Trial Updated:
05/25/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Metabolic Disorders, Cancer, Chronic Kidney Disease, Diabetes, Normal Physiology
Register for Updates
The Effect of Clinic Visit Audio Recordings for Self-management in Older Adults
NCT05824572
Recruiting
The objective of this study is to conduct a multisite trial evaluating the impact of adding an audio recording of clinic visits (AUDIO) to usual care in older adults with multimorbidity, including diabetes, compared to After Visit Summary (AVS) alone (Usual Care; UC).
Gender:
All
Ages:
65 years and above
Trial Updated:
05/24/2024
Locations: Dartmouth-Hitchcook Manchester, Manchester, New Hampshire +2 locations
Conditions: Diabetes
Register for Updates
Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes
NCT06401876
Recruiting
The purpose of this research is to obtain blood samples before and after a bariatric procedure to better understand the reasons for glucose intolerance and insulin resistance (diabetes) in the obesity, and the reasons for improvement of diabetes after bariatric surgery
Gender:
All
Ages:
21 years and above
Trial Updated:
05/20/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Glucose Intolerance, Insulin Resistance, Diabetes
Register for Updates
Taste Bud-Derived Stem Cells in Humans
NCT03366168
Recruiting
Background: Stem cells are found in body tissues. They can regenerate into more of the same cells or become other types of cell. Researchers want to use stem cells from taste buds to try to make cells that secrete insulin. Taste buds are found mostly on the tip and sides of the tongue. Researchers also want to study if the number of taste buds and stem cells decrease as people age. They will remove small pieces of tongue tissue (about the size of a pen tip). The taste buds will grow back. It is... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
05/17/2024
Locations: National Institute of Aging, Clinical Research Unit, Baltimore, Maryland
Conditions: Diabetes
Register for Updates
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
NCT04984226
Recruiting
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
Gender:
All
Ages:
Between 21 years and 85 years
Trial Updated:
05/16/2024
Locations: University of California Davis Health, Sacramento, California +1 locations
Conditions: Chronic Kidney Diseases, Metabolic Acidosis, Fatigue, Physical Endurance, Insulin Resistance, Mitochondrial Energetics, Diabetes
Register for Updates
Pancreatic Islet Transplantation Into the Anterior Chamber of the Eye
NCT02846571
Recruiting
The treatment in this trial consists of intraocular islet transplantation. A single dose of 1000 - 2000 Islet Equivalents (IEQ)/kg recipient body weight (BW) will be infused into the anterior chamber of the eye through a self-sealing incision of the peripheral cornea. The procedure is projected to take approximately 20-30 minutes. Subject will remain flat on their back for 1-3 hours after islet infusion to maximize adhesion of the islets to the iris.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/15/2024
Locations: Bascom Palmer Eye Institute, Miami, Florida +1 locations
Conditions: Diabetes
Register for Updates
OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection
NCT06343350
Recruiting
In the United States, only 62% of the 37 million people with diabetes receive annual screening exams for diabetic retinopathy. One of the goals of the US Department of Health and Human Services Healthy People 2030 campaign is to increase diabetic retinopathy screening rates to 70.3%. Research indicates that low screening rates are associated with a variety of factors, including income levels, race and lack of access to care. Furthermore, because diabetic retinopathy frequently presents asymptoma... Read More
Gender:
All
Ages:
22 years and above
Trial Updated:
05/13/2024
Locations: Triwest Research Associates, San Diego, California +1 locations
Conditions: Diabetic Retinopathy, Diabetes
Register for Updates
Caregiving Networks Across Disease Context and the Life Course
NCT05007990
Recruiting
Background: In the U.S., about 53 million informal, unpaid caregivers provide care to a person who is ill, is disabled, or has age-related loss of function. These caregivers may be adult children, spouses, parents, or others. The stress of providing long-term care affects caregivers health and well-being. Researchers want to learn more about this stress and its effects. Objective: To learn how the caregiving process affects the health and well-being of caregivers over time. Eligibility: Adu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Inherited Metabolic Disorders, Undiagnosed Diseases, Batten's Disease, Tay Sachs, Diabetes
Register for Updates
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
NCT03012529
Recruiting
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to o... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
05/06/2024
Locations: Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona +29 locations
Conditions: Osteomyelitis, Diabetes, Amputation
Register for Updates
Ultrasound Findings in Diabetic Pregnancies
NCT06407388
Recruiting
The goal of our study is to identify ultrasonographic markers that can predict adverse neonatal outcomes. Specifically, we hypothesize that an increase in fetal liver volumes will increase transcutaneous bilirubin (TcB) in the newborn and thus jaundice requiring phototherapy. This information can be used in patient counseling and to guide future screening protocols for ultrasound in individuals with diabetes.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
05/06/2024
Locations: Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Eastern Virginia Medical School, Norfolk, Virginia
Conditions: Diabetes
Register for Updates
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
NCT06190717
Recruiting
This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula maturation and reducing time to Clinical Maturation.
Gender:
All
Ages:
Between 18 years and 84 years
Trial Updated:
05/06/2024
Locations: Trinity Research Group, Dothan, Alabama +3 locations
Conditions: Diabetes, End Stage Renal Disease
Register for Updates
Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.
NCT04757519
Recruiting
This study seeks to establish the efficacy of identifying weight loss nonresponders early in a Diabetes Prevention Program (DPP) intervention in 20 community settings (primarily churches and community centers) and providing them with individual-level, enhanced treatment through telephone contacts and access to additional resources. Additionally, potential mediators and moderators of the relationship between intervention status and weight loss response at 6 months in both nonresponders and respon... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: First Corinthian Baptist Church, Frankfort, Kentucky +19 locations
Conditions: Diabetes
Register for Updates