There are currently 79 active clinical trials seeking participants for Diabetes research studies. The states with the highest number of trials for Diabetes participants are California, Texas, Florida and Pennsylvania.
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
NCT02262832
Recruiting
Background: - Generalized lipodystrophy can cause high blood fat levels and resistance to insulin. This can lead to health problems including diabetes. Researchers have found that the drug metreleptin improves health in people with this disease. Objective: - To test the safety and effectiveness of metreleptin. Eligibility: * People ages 6 months and older with generalized lipodystrophy who: * have received metreleptin through NIH studies AND * cannot get it through approved or compassionate... Read More
Gender:
ALL
Ages:
Between 6 months and 98 years
Trial Updated:
06/14/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Lipodystrophy, Diabetes, Hyperlipidemia
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Caregiving Networks Across Disease Context and the Life Course
NCT05007990
Recruiting
Background: In the U.S., about 53 million informal, unpaid caregivers provide care to a person who is ill, is disabled, or has age-related loss of function. These caregivers may be adult children, spouses, parents, or others. The stress of providing long-term care affects caregivers health and well-being. Researchers want to learn more about this stress and its effects. Objective: To learn how the caregiving process affects the health and well-being of caregivers over time. Eligibility: Adu... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/13/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Inherited Metabolic Disorders, Undiagnosed Diseases, Batten's Disease, Tay Sachs, Diabetes
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Mitigating the Pro-inflammatory Phenotype of Obesity
NCT04934228
Recruiting
The purpose of this study is to examine the hypothesize that 4 weeks of sympathetic nerve activity (SNA) inhibition (oral clonidine) will cause a significant reduction in circulating blood concentrations and endothelial cell expression of inflammatory markers (e.g., TNF-α, IL-6). Our study is a prospective study using a randomized, double-blinded design to test 4 weeks of SNA blockade (oral clonidine) compared with a BP-lowering control condition (diuretic, hydrochlorothiazide) or a placebo.
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
06/04/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Blood Pressure, Diabetes, Obesity, Insulin Resistance, Diuretics Drug Reactions, Sympathetic Nerve Activity
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Mechanisms Underlying Impaired Diabetic Wound Healing
NCT00777712
Recruiting
The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
06/02/2025
Locations: Comprehensive Wound Care Centers, Indianapolis, Indiana +4 locations
Conditions: Non-healing Wounds, Diabetes
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Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
NCT06140537
Recruiting
Long-term allograft function in kidney transplant recipients (KTRs) remain suboptimal, and graft failure causes significant morbidity and mortality, with cardiovascular disease being the leading cause of death in KTRs and the most common cause of death with a functioning graft. Sodium-glucose cotransporter 2 (SGLT2) inhibitors safely lower cardiovascular and kidney disease risk in the non-transplant population, yet data in KTRs are lacking. This clinical trial seeks to establish the efficacy and... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/28/2025
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Kidney Transplant; Complications, Vascular Diseases, Diabetes
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Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
NCT06557005
Recruiting
The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the \>30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care engagement, quality, and experience by strengthening postpartum transitions to primary care using a behavioral economics-informed, multi-component intervention integrated into usual inpatient postpartum c... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/27/2025
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Hypertension, Diabetes, Postpartum, Pregnancy, Anxiety, Depression, Obesity
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Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes Among Socioeconomically Disadvantaged Communities
NCT06763952
Recruiting
This study aims to investigate whether a novel artificial intelligence based screening strategy (AI-Based point of caRe, Incorporating Diagnosis, SchedulinG, and Education or AI-BRIDGE), which allows primary care providers to screen patients for vision-threatening diabetic eye disease in the primary care clinic, improves screening and follow-up care rates across race/ethnicity groups and reduces racial/ethnic disparities in screening.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
05/23/2025
Locations: UW School of Medicine and Public Health, Madison, Wisconsin
Conditions: Vision, Diabetes
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Maternal Abdominal Morphology Assessment
NCT06784674
Recruiting
Previous studies have shown that pancreas size tends to be smaller in individuals with diabetes compared to those without diabetes. The investigators have recently found that pancreas size increases during pregnancy. The MAMA study aims to examine changes in the pancreas that occur during pregnancy, in both pregnant mothers and their babies, and find out how they are affected by maternal diabetes. The MAMA study is a prospective cohort study that will follow women and their babies through pregn... Read More
Gender:
FEMALE
Ages:
Between 18 years and 54 years
Trial Updated:
05/23/2025
Locations: Dell Medical School Health Discovery Building, Austin, Texas
Conditions: Pregnancy Related, Infant Development, Pancreas, Diabetes
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Salud Diabetes: A Pilot Study Comparing Lifestyle Interventions and Real-Time Continuous Glucose Monitoring
NCT06999356
Recruiting
The aim of this proposal is to determine the impact of a produce prescription program in predominantly Hispanic/Latino adults with established non-insulin treated T2D and an HbA1c at or above 9%.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/22/2025
Locations: Sansum Clinic, Sutter Health, Santa Barbara, California
Conditions: Diabetes, Nutrition
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Community Engagement Alliance Against Disparities
NCT06607341
Recruiting
The Community Engagement Alliance against Disparities - Washington District of Columbia, Maryland, Virginia (CEAL DMV), is a multi-community and multi-university consortium. Through collaboration and shared leadership, the CEAL-DMV the consortium- comprising five institutions: George Washington University, Howard University, Johns Hopkins University, Morgan State University, and the University of Maryland, Baltimore-has established a regional structure for bi-directional community involvement to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: George Washington University, Milken Institute of Public Health, Washington, District of Columbia +1 locations
Conditions: Diabetes, Pre-diabetes, Hypertension, Overweight and Obesity
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Delta GREENS Food is Medicine Intervention
NCT06358859
Recruiting
Though the Mississippi Delta has a rich agricultural history and some of the nation's most fertile soil, residents have experienced the legacy of slavery and economic exploitation through food insecurity and poverty for generations. This project focuses on Bolivar, Washington, and Sunflower, contiguous counties in the Delta that are designated as health disparity populations. Over 65% of the 100,000 residents are Black/African American and \~30% live at or below the poverty level. Obesity rates... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
05/20/2025
Locations: Tufts University, Boston, Massachusetts
Conditions: Cardiometabolic Risk Factors, Diabetes, High Blood Pressure, Obesity, Nutrition Security
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Remote Fetal Monitoring in High Risk Pregnancies
NCT06822439
Recruiting
Antenatal nonstress tests (NSTs) are performed to assess fetal health and are used as a cost-effective test that can be widely administered. However, an NST is operator-dependent due to the nature of Doppler ultrasound and is primarily performed in a clinic and hospital setting. The ability to conduct a clinically valuable test at home would address access to care issues faced by numerous women in the United States and reduce the workload on healthcare clinicians facing a shortage of human reso... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/19/2025
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: High Risk Pregnancy, Remote Patient Monitoring, Diabetes, Hypertension
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