There are currently 76 active clinical trials seeking participants for Diabetes research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and Pennsylvania.
GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance
NCT04731272
Recruiting
Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced β-cell mass contributes to the insulin secretory defects that characterizes cystic fibrosis-related diabetes (CFRD), other modifiable determinants appear operative in the emergence and progression of abnormal glucose tolerance towards diabetes. Identifying interventions to preserve β-cell function are crucial for delaying and potentially preventing CFRD developmen... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Cystic Fibrosis, Pancreatic Insufficiency, Abnormal Glucose Tolerance, Diabetes
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Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
NCT02262832
Recruiting
Background: - Generalized lipodystrophy can cause high blood fat levels and resistance to insulin. This can lead to health problems including diabetes. Researchers have found that the drug metreleptin improves health in people with this disease. Objective: - To test the safety and effectiveness of metreleptin. Eligibility: People ages 6 months and older with generalized lipodystrophy who: have received metreleptin through NIH studies AND cannot get it through approved or compassionate use m... Read More
Gender:
All
Ages:
Between 6 months and 98 years
Trial Updated:
02/23/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Lipodystrophy, Diabetes, Hyperlipidemia
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Trial to Assess Chelation Therapy in Critical Limb Ischemia
NCT03982693
Recruiting
TACT3a is a double blind, placebo-controlled, randomized trial to test a novel therapy, edetate disodium-based chelation of environmentally acquired toxic metals, to reduce cardiovascular events including amputation in high-risk diabetic patients.
Gender:
All
Ages:
50 years and above
Trial Updated:
02/23/2024
Locations: Mount Sinai Medical Center, Miami Beach, Florida
Conditions: Critical Limb Ischemia, Diabetes
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Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
NCT06140537
Recruiting
Long-term allograft function in kidney transplant recipients (KTRs) remain suboptimal, and graft failure causes significant morbidity and mortality, with cardiovascular disease being the leading cause of death in KTRs and the most common cause of death with a functioning graft. Sodium-glucose cotransporter 2 (SGLT2) inhibitors safely lower cardiovascular and kidney disease risk in the non-transplant population, yet data in KTRs are lacking. This clinical trial seeks to establish the efficacy and... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/15/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Kidney Transplant; Complications, Vascular Diseases, Diabetes
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T1DTechCHW: Enhancing the Community Health Worker Model to Promote Diabetes Technology Use in Young Adults From Underrepresented Minority Groups
NCT05211869
Recruiting
The objective of this study is to test the early effects and implementation of an enhanced community health worker (CHW) model (T1D-CATCH) that encourages and supports diabetes technology use in young adults from underrepresented minority groups (YA-URMs) with type 1 diabetes (T1D). The investigators will conduct a 9-month randomized controlled trial in which YA-URMs will be randomized to T1D-CATCH or usual care. The investigators will recruit from adult and pediatric endocrinology and primary c... Read More
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
02/15/2024
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Diabetes, Type 1 Diabetes, Young Adult, Diabetes Mellitus
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Imaging the Pathogenesis of Cerebral Small Vessel Disease
NCT05703386
Recruiting
Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Ischemic Stroke, Hypertension, Hyperlipidemias, Diabetes
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A Study of Non-invasive Measurement of Blood Glucose and Blood Pressure
NCT05904769
Recruiting
The purpose of this research is to compare blood glucose, blood pressure and electrocardiogram (ECG) readings on the LIFELEAF Smartwatch compared to standard methods of measurement.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Diabetes
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EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds
NCT03960463
Recruiting
The investigators will test the efficacy of the novel oxygen diffusion dressing allows delivery tissue oxygenation via TransCu O2® Oxygen Delivery System for use in caring for patients with surgically closed wounds. The investigators hypothesize that using this novel oxygen diffusion dressing will reduce the likelihood of necrotic tissue as well as severe incisional scar post-surgical closure by improving transcutaneous oxygen levels during wound healing process. TransCu O2 Oxygen Delivery Syst... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/10/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Surgical Wound, Diabetes, Amputation Wound, Incision Wound, Peripheral Arterial Disease, Breast Cancer, Diabetic Foot
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Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health
NCT06065098
Recruiting
Cardiovascular disease (CVD) is the leading cause of death in the US general population. Although CVD mortality rates declined for both Black and White populations during the past two decades, they are still higher in Black adults than White adults. There are also persistent disparities in CVD risk factors with higher prevalence of obesity, hypertension, and diabetes in Black compared to White populations. In addition, CVD and risk factors are more prevalent in the residents of Louisiana compare... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
01/02/2024
Locations: Tulane University, New Orleans, Louisiana
Conditions: Cardiovascular Diseases, Hypertension, Diabetes, Hypercholesterolemia
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Efficacy of Viome's Precision Nutrition Program Towards Reducing HbA1c
NCT06185192
Recruiting
This is a randomized, placebo-controlled trial that will test the efficacy of VPNP in reducing HbA1c. Participant recruitment will occur through direct-to-participant enrollment. No additional clinical sites will be used for recruitment.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/02/2024
Locations: Viome Life Sciences, Bothell, Washington
Conditions: Diabetes
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Enhanced DPP-GLB to Promote Weight Loss Among Nonresponders in a Community-Based Lifestyle Intervention.
NCT04757519
Recruiting
This study seeks to establish the efficacy of identifying weight loss nonresponders early in a Diabetes Prevention Program (DPP) intervention in 20 community settings (primarily churches and community centers) and providing them with individual-level, enhanced treatment through telephone contacts and access to additional resources. Additionally, potential mediators and moderators of the relationship between intervention status and weight loss response at 6 months in both nonresponders and respon... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/18/2023
Locations: First Corinthian Baptist Church, Frankfort, Kentucky +15 locations
Conditions: Diabetes
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Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children
NCT05473767
Recruiting
This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants. The investigators will adapt a cardiovascular health intervention into an evidence-based home visiting program, Family Check-Up to create Family Check-Up Heart. Through a Type 1 hybrid effectiveness implementation design, the pilot study will test the feasibility and effectiveness of Family Check-Up Heart (Family Check-Up Heart, n=100; Family Check-Up,... Read More
Gender:
All
Ages:
All
Trial Updated:
12/12/2023
Locations: Healthy Start, Inc., Pittsburgh, Pennsylvania +2 locations
Conditions: Obesity, Maternal, Hypertension in Pregnancy, Hypertension, Pregnancy-Induced, Diabetes, Overweight
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