There are currently 79 active clinical trials seeking participants for Diabetes research studies. The states with the highest number of trials for Diabetes participants are California, Texas, Florida and Pennsylvania.
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
NCT03012529
Recruiting
The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at a high risk for needing an amputation of part of the foot or lower leg because the osteomyelitis is not cured. Some small research studies have shown that addition of rifampin to o... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/14/2025
Locations: Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona +29 locations
Conditions: Osteomyelitis, Diabetes, Amputation
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Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
NCT04984226
Recruiting
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
Gender:
ALL
Ages:
Between 21 years and 85 years
Trial Updated:
05/09/2025
Locations: University of California Davis Health, Sacramento, California +1 locations
Conditions: Chronic Kidney Diseases, Metabolic Acidosis, Fatigue, Physical Endurance, Insulin Resistance, Mitochondrial Energetics, Diabetes
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A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
NCT05321368
Recruiting
The LINKED- HEARTS Program is a multi-level project that intervenes at the practice level by linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo). The program incorporates team-based care by including community health workers (CHWs) and pharmacists to improve the outcomes of multiple chronic conditions (reduced blood pressure (BP), lower blood sugar, and improved kidney function). The LINKED-HEARTS Program will recruit a total of 600 adults with uncontrolled hyp... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/05/2025
Locations: Unity Health Care, Washington, District of Columbia +2 locations
Conditions: Hypertension, High Blood Pressure, Diabetes, Chronic Kidney Diseases
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GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance
NCT04731272
Recruiting
Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced β-cell mass contributes to the insulin secretory defects that characterizes cystic fibrosis-related diabetes (CFRD), other modifiable determinants appear operative in the emergence and progression of abnormal glucose tolerance towards diabetes. Identifying interventions to preserve β-cell function are crucial for delaying and potentially preventing CFRD developmen... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Children's Hospital of Colorado, Aurora, Colorado +1 locations
Conditions: Cystic Fibrosis, Pancreatic Insufficiency, Abnormal Glucose Tolerance, Diabetes
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Personalized Responses to Dietary Composition Trial 3
NCT04735835
Recruiting
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of testing postprandial responses to specific mixed meals, in addition to a free-living period with a dietary record for measuring responses to a large v... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2025
Locations: Zoe US Inc., Needham, Massachusetts +1 locations
Conditions: Diabetes, Heart Diseases, Diet Habit, Diet Modification, Healthy, Obesity, Metabolism, Microbial Colonization
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Effect of 2-Week Continuous Glucose Monitoring on Glycemic Management in Patients New-to-Insulin on Hospital Discharge
NCT05548205
Recruiting
The proposed study will be a randomized, prospective, non-blinded study of 120 participants with type 1 or type 2 diabetes that are new-to-insulin on hospital discharge. On hospital discharge, participants will be assigned to either the intervention of wearing a continuous glucose monitor (CGM) for 2 weeks or blood glucose monitoring (BGM) for 2 weeks. They will have a 2-week follow up visit, during which insulin doses will be adjusted as needed, and a 3-month follow-up visit, at which point HbA... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/09/2025
Locations: NYU Langone Hospital - Long Island, Mineola, New York
Conditions: Diabetes
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FIT-COACH: Fitbit Intervention With Coordinated Health Coaching and PCP Support
NCT06915090
Recruiting
In individuals with overweight/obesity, increases in physical activity (PA) can improve metabolic and cardiovascular health, independent of weight loss. However, PA levels are often low in individuals with overweight/obesity, and primary care providers (PCPs) are tasked with addressing this issue. The investigative team developed and successfully piloted integrating a Fitbit program into clinical care, where patients were referred by PCPs, and PCPs could view PA data in the Epic electronic healt... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/03/2025
Locations: UMass Chan Medical School, Worcester, Massachusetts
Conditions: GLP - 1, Diabetes, Obesity and Obesity-related Medical Conditions, Cardiovascular Diseases
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Dietary Intervention to Improve Kidney Transplant Outcomes
NCT05449496
Recruiting
Randomized controlled trial of a curriculum intervention teaching patients to eat a whole-food plant-based dietary pattern versus standard of care in kidney transplant recipients within the first few months of transplant
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: UC Davis, Sacramento, California
Conditions: Kidney Transplant; Complications, Kidney Diseases, Transplant;Failure,Kidney, Diabetes, Hypertension, Obesity, Diet, Healthy, Lifestyle, Healthy
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Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health
NCT06065098
Recruiting
Cardiovascular disease (CVD) is the leading cause of death in the US general population. Although CVD mortality rates declined for both Black and White populations during the past two decades, they are still higher in Black adults than White adults. There are also persistent disparities in CVD risk factors with higher prevalence of obesity, hypertension, and diabetes in Black compared to White populations. In addition, CVD and risk factors are more prevalent in the residents of Louisiana compare... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2025
Locations: Tulane University, New Orleans, Louisiana
Conditions: Cardiovascular Diseases, Hypertension, Diabetes, Hypercholesterolemia
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A Natural History Study of Metabolic Sizing in Health and Disease
NCT05398783
Recruiting
Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metabolism varies among people with similar body sizes. Scientists now believe the old formulas for estimating metabolic rates may not work well for all people. Researchers want to find more accurate ways to measure a person s metabolism. Objective: This natural history study will examine the relations... Read More
Gender:
ALL
Ages:
Between 2 years and 99 years
Trial Updated:
03/25/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Metabolic Disorders, Cancer, Chronic Kidney Disease, Diabetes, Normal Physiology
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OPTDR01 Feasibility for Automated Diabetic Retinopathy Detection
NCT06343350
Recruiting
In the United States, only 62% of the 37 million people with diabetes receive annual screening exams for diabetic retinopathy. One of the goals of the US Department of Health and Human Services Healthy People 2030 campaign is to increase diabetic retinopathy screening rates to 70.3%. Research indicates that low screening rates are associated with a variety of factors, including income levels, race and lack of access to care. Furthermore, because diabetic retinopathy frequently presents asymptoma... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/24/2025
Locations: Gastro SB, Chula Vista, California +3 locations
Conditions: Diabetic Retinopathy, Diabetes
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Together Overcoming Diabetes - Great Plains
NCT06770673
Recruiting
The goal of this research is to evaluate a scientifically rigorous diabetes intervention, Together Overcoming Diabetes (TOD), that has been tailored to address the unique underlying risk and protective factors and social determinants of diabetes among American Indian/Alaska Native (AI/AN) populations.
Gender:
ALL
Ages:
10 years and above
Trial Updated:
03/24/2025
Locations: Center for Indigenous Health - Great Plains Hub, Rapid City, South Dakota
Conditions: Diabetes
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