There are currently 37 active clinical trials seeking participants for Fibromyalgia research studies. The states with the highest number of trials for Fibromyalgia participants are Florida, California, Ohio and Texas.
Low-Intensity Focused Ultrasound For Insular Neuromodulation in Chronic Pain
Recruiting
Study investigating the potential benefit for chronic pain patients (CRPS and FM) using low-intensity focused ultrasound for neuromodulation.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/12/2023
Locations: Fralin Biomedical Research Institute, Roanoke, Virginia
Conditions: Fibromyalgia, Complex Regional Pain Syndromes, Chronic Pain
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/14/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia, Rheumatoid Arthritis
Chromatic Retinal Stimulation to Reduce Chronic Pain and Pain Sensitivity
Recruiting
Participants with chronic pain conditions including chronic low back pain and fibromyalgia may benefit from light stimuli presented to the retina to reduce chronic pain severity and pain sensitivity. Participants will be recruited into this study and will be presented with one of three uniform light stimuli via a wide-field ganzfeld in three conditions to determine the retinal mechanisms that reduce pain. This work will lead to a greater understanding of retinal mechanisms that contribute to pai... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/12/2024
Locations: University Of North Carolina, Chapel Hill, North Carolina
Conditions: Chronic Low-back Pain, Chronic Pain, Fibromyalgia
Sleep and Pain Interventions in Women With Fibromyalgia
Recruiting
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia. This trial will yield important information about the roles of sleep, arousal, and brain structure and function in the development and maintenance of chronic pain in women with fibromyalgia.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: University of Missouri- Department of Psychiatry, Columbia, Missouri
Conditions: Fibromyalgia, Insomnia, Chronic Widespread Pain
Effects of Breathing and Attention Training (BAT) on Pain Modulation
Recruiting
The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will be used to evaluate the effects of Breathing Attention Training (BAT) on the hypersensitivity of FM participants. BAT is a form of mindfulness meditation show... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/24/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia
Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial
Recruiting
The purpose of this study is to determine if addition of Transcutaneous Electrical Nerve Stimulation (TENS) to routine physical therapy improves movement-evoked pain in patients with fibromyalgia (FM). The study will also determine if addition of TENS to routine physical therapy (PT) improves disease activity and symptoms, increases adherence to physical therapy, increases the likelihood of meeting patient specific functional goals, and reduces medication use.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/22/2024
Locations: University of Illinois at Chicago, Chicago, Illinois +5 locations
Conditions: Fibromyalgia
Nitrous Oxide as Treatment for Fibromyalgia
Recruiting
The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/06/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Fibromyalgia, Central Neuropathic Pain
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
Recruiting
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/03/2024
Locations: Sanguine Biosciences, Waltham, Massachusetts
Conditions: Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease, Amyloidosis, Ankylosing Spondylitis, Arthritis, Alopecia Areata, Asthma, Atopic Dermatitis, Autism, Autoimmune Hepatitis, Behcet's Disease, Beta-Thalassemia, Cancer, Celiac Disease, Kidney Diseases, COPD, Crohn Disease, Cystic Fibrosis, Diabetes, Dravet Syndrome, DMD, Fibromyalgia, Graves Disease, Thyroid Diseases, Hepatitis, Hidradenitis Suppurativa, ITP, Leukemia, ALS, Lupus or SLE, Lymphoma, Multiple Sclerosis, Myasthenia Gravis, Heart Diseases, Parkinson Disease, Pemphigus Vulgaris, Cirrhosis, Psoriasis, Schizophrenia, Scleroderma, Sickle Cell Disease, Stroke, Ulcerative Colitis, Vasculitis, Vitiligo
Treatment of Fibromyalgia With the FibroNova Neuromodulation Device
Recruiting
Fibromyalgia (FM) is a chronic disorder that affects the musculoskeletal system, causing widespread pain, tenderness, and fatigue. It is estimated to affect 1-5% of the population. The primary symptom of fibromyalgia is widespread pain throughout the body, accompanied by tenderness and sensitivity to pressure. Pharmacological treatments include drugs such as antidepressants, anticonvulsants, and painkillers. Another treatment option for fibromyalgia is the use of devices such as Quell. Other no... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/09/2024
Locations: Clinical Research Professionals, Chesterfield, Missouri +3 locations
Conditions: Fibromyalgia
Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder with unknown causes. Our previous studies showed abnormal sensations of second pain (wind-up), indicating central hypersensitivity as an important mechanism of FM. Triggering events have been implicated as the cause of central hypersensitivity.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/08/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia
Mechanisms of Affective Touch in Chronic Pain
Recruiting
This study compares how different types of touch found in massage therapies impact pain perception, and whether these effects differ in individuals with and without chronic pain. This study also examines psychological factors that may predict differences in touch perception in individuals with chronic pain. This research will improve our understanding of whether and how massage therapies can benefit pain and health, and whether this differs in people who suffer from chronic pain.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/01/2024
Locations: ACTRI, La Jolla, California
Conditions: Fibromyalgia
Explosive Synchronization of Brain Network Activity in Chronic Pain
Recruiting
This project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM). The study design has three components, however, only 2 aims are enrolling participants. The first part (Aim1) is a cross sectional assessment of brain network explosive synchronization activity, connectivity, and response to pain in healthy controls and age and sex-matched fibromyalgia patients; the third part (Aim 3) is a longitudin... Read More
Gender:
All
Ages:
Between 19 years and 74 years
Trial Updated:
03/27/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Fibromyalgia, Healthy Volunteers