There are currently 37 active clinical trials seeking participants for Fibromyalgia research studies. The states with the highest number of trials for Autism participants are Florida, California, Ohio and Texas.
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
NCT05754190
Recruiting
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary goal of the study is to use fluctuations in daily self-reported symptoms to identify computational predictors of acute-chronic pain transition, pain recovery, and/or chronic pain maintenance or flareups. The general study will include anyone with current acute or chronic p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: Brown University, Providence, Rhode Island
Conditions: Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
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Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
NCT05277025
Recruiting
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia, Rheumatoid Arthritis
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Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial
NCT04683042
Recruiting
The purpose of this study is to determine if addition of Transcutaneous Electrical Nerve Stimulation (TENS) to routine physical therapy improves movement-evoked pain in patients with fibromyalgia (FM). The study will also determine if addition of TENS to routine physical therapy (PT) improves disease activity and symptoms, increases adherence to physical therapy, increases the likelihood of meeting patient specific functional goals, and reduces medication use.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/01/2023
Locations: University of Illinois at Chicago, Chicago, Illinois +5 locations
Conditions: Fibromyalgia
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Effects of Breathing and Attention Training (BAT) on Pain Modulation
NCT05773482
Recruiting
The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will be used to evaluate the effects of Breathing Attention Training (BAT) on the hypersensitivity of FM participants. BAT is a form of mindfulness meditation show... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/09/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Fibromyalgia
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Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
NCT05491499
Recruiting
This work will answer two critical questions: 1) Does intensive interdisciplinary pain treatment (IIPT) involving aerobic exercise help normalize pain processing in youth with chronic pain syndromes and 2) Are aerobic fitness levels and the ability to modulate pain inter-related? Currently, medications are ineffective for improving pain and disability in youth with chronic pain syndromes and identifying non-pharmacologic treatments, such as IIPT, that help strengthen the nervous system's abilit... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
02/08/2023
Locations: Boston Children's Hospital at Waltham, Waltham, Massachusetts
Conditions: Chronic Pain Syndrome, Fibromyalgia, Chronic Headache Disorder, Functional Abdominal Pain Syndrome, Complex Regional Pain Syndromes
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Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
NCT04833465
Recruiting
The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This would enable objective assessment of pain and treatment in these populations and enable a much more precise approach to treatment. Such an endpoint stands to significantly improve outcomes in these patients by eliminating the need for a trial-and-error approach to treatment. This is a single site observational study that aims to collect ini... Read More
Gender:
All
Ages:
Between 5 years and 21 years
Trial Updated:
01/31/2023
Locations: Children's National Health System, Washington, District of Columbia
Conditions: Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Fibromyalgia
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A Single-Site Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
NCT05635266
Recruiting
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/22/2022
Locations: Sanguine Biosciences, Waltham, Massachusetts
Conditions: Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease, Amyloidosis, Ankylosing Spondylitis, Arthritis, Alopecia Areata, Asthma, Atopic Dermatitis, Autism, Autoimmune Hepatitis, Behcet's Disease, Beta-Thalassemia, Cancer, Celiac Disease, Kidney Diseases, COPD, Crohn Disease, Cystic Fibrosis, Diabetes, Dravet Syndrome, DMD, Fibromyalgia, Graves Disease, Thyroid Diseases, Hepatitis, Hidradenitis Suppurativa, ITP, Leukemia, ALS, Lupus or SLE, Lymphoma, Multiple Sclerosis, Myasthenia Gravis, Heart Diseases, Parkinson Disease, Pemphigus Vulgaris, Cirrhosis, Psoriasis, Schizophrenia, Scleroderma, Sickle Cell Disease, Stroke, Ulcerative Colitis, Vasculitis, Vitiligo
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Study of Low-dose Naltrexone in Chronic Migraine With Fibromyalgia
NCT05536050
Recruiting
This research aims to look at the effect of low-dose naltrexone on the severity and frequency of attacks in people with chronic migraine with or without new daily persistent headache and fibromyalgia. A few studies suggest low-dose naltrexone is effective for fibromyalgia, but it has not been studied in patients with migraine and headaches. Our goal is to see if there is an improvement in either severity and frequency of attacks and overall impact on quality of life over a three-month period.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2022
Locations: Jefferson Headache Center, Philadelphia, Pennsylvania
Conditions: Chronic Migraine, Fibromyalgia, New Daily Persistent Headache
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Outcomes Mandate National Integration With Cannabis as Medicine
NCT03944447
Recruiting
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/29/2022
Locations: OMNI Medical Services, Boca Raton, Florida +16 locations
Conditions: Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma, Fibromyalgia, Seizures, Hepatitis C, Cancer, Crohn Disease, HIV/AIDS, Multiple Sclerosis, Traumatic Brain Injury, Sickle Cell Disease, Post Traumatic Stress Disorder, Tourette Syndrome, Ulcerative Colitis, Glaucoma, Epilepsy, Inflammatory Bowel Diseases, Parkinson Disease, Amyotrophic Lateral Sclerosis, Chronic Traumatic Encephalopathy, Anxiety, Depression, Insomnia, Autism, Opioid-use Disorder, Bipolar Disorder, Covid19, SARS-CoV Infection, COVID-19, Corona Virus Infection, Coronavirus
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Enhancing Analgesia in Chronic Pain Through Exercise
NCT04862871
Recruiting
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies. To date, experiencing a painful stimulus has been known to disrupt motor activity in an attempt to minimize injury. However, physical activity, even when it increases ongoing pain initially, has been shown to significantly reduce pain symptoms eventually through neuromodulation. In both acute and chronic pain cohorts, exercise protocols and neuromodulatio... Read More
Gender:
All
Ages:
Between 10 years and 24 years
Trial Updated:
05/06/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Pain, Chronic Widespread Pain, Fibromyalgia
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Nitrous Oxide as Treatment for Fibromyalgia
NCT05357066
Recruiting
The purpose of this study is to explore a potential role of nitrous oxide in treating pain associated with fibromyalgia.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/26/2022
Locations: University of Chicago, Chicago, Illinois
Conditions: Fibromyalgia, Central Neuropathic Pain
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Delivery of Enhance Fitness Trial
NCT05275348
Recruiting
Arthritis is a common condition in the United States, and a leading cause of pain and disability. Physical exercise is recommended for managing arthritis, but access to evidence-based exercise programs is limited, particularly in rural areas. Therefore, the investigators propose to evaluate remote delivery of an evidence-based exercise program called Enhance Fitness (EF) that is recommended for arthritis management. The primary purpose of this study is to determine if remotely delivered EF is no... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/01/2022
Locations: University of Washington, Seattle, Washington
Conditions: Arthritis, Rheumatoid Arthritis, Fibromyalgia, Gout, Osteoarthritis, Lupus or SLE
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