There are currently 31 active clinical trials seeking participants for Fibromyalgia research studies. The states with the highest number of trials for Fibromyalgia participants are Florida, California, Ohio and Texas.
Supraspinal Processing of Sensory Aspects of Pain
NCT05814497
Recruiting
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients. The main questions it aims to answer are: * Are there shared and distinct brain systems engaged by different forms of pediatric chronic pain? * What are predictors of recovery from chronic pain? * What brain systems are associated with the spread of pain? For this study participants will undergo: * Functional Magnetic Resonance Imaging (fMR... Read More
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
01/03/2025
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome, Fibromyalgia
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The Effects of Core Shamanism in Fibromyalgia
NCT06579261
Recruiting
This study aims to determine the feasibility of a shamanism intervention for patients with fibromyalgia, acquire efficacy data to determine if Shamanism reduces clinical pain and other common symptoms associated with fibromyalgia, and determine if the Shamanism intervention changes heart rate electrocardiogram (ECG), breathing rate, and brain wave electroencephalogram (EEG) outcomes in fibromyalgia patients and shamanic practitioners. The investigators hypothesize that 80% of individuals will c... Read More
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
05/22/2025
Locations: Susan Samueli Integrative Health Institute, Irvine, California
Conditions: Fibromyalgia
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Duloxetine Metabolism and Fibromyalgia
NCT06866444
Recruiting
People with fibromyalgia report generalized body pain ("pain all over"), increased sensitivity to painful stimulation, chronic tiredness or low energy, sleep problems, and other physical and functional problems. The exact cause of the disorder is poorly understood, and treatment can be difficult. The degree to which duloxetine is helpful for people with fibromyalgia varies greatly. For some people, it is very helpful for managing fibromyalgia symptoms. For others, people may not notice any bene... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Pain Management Center and Pain Research Center at the University of Utah, Salt Lake City, Utah
Conditions: Fibromyalgia, Duloxetine
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Explosive Synchronization of Brain Network Activity in Chronic Pain
NCT04606095
Recruiting
This project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM). The study design has three components, however, only 2 aims are enrolling participants. The first part (Aim1) is a cross sectional assessment of brain network explosive synchronization activity, connectivity, and response to pain in healthy controls and age and sex-matched fibromyalgia patients; the third part (Aim 3) is a longitudin... Read More
Gender:
ALL
Ages:
Between 19 years and 74 years
Trial Updated:
05/07/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Fibromyalgia, Healthy Volunteers
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Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients
NCT06009159
Recruiting
Fibromyalgia (FM) is a syndrome with clinical symptoms involving multiple systems. The efficacy of current treatments is inadequate, and more alternative modalities are needed for the management of FM patients. The parasympathetic vagus nerve innervates and integrates sensory, motor, and autonomic systems and has been suggested to play a role in pain modulation. The role of vagus nerve stimulation (VNS) as a treatment option for FM patients is yet to be investigated. The investigators propose to... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/05/2025
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Fibromyalgia
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Analgesic Response to Opioids in Patients With Fibromyalgia After Conventional Acupuncture Versus Sham Acupuncture
NCT06571110
Recruiting
This study aims to see whether acupuncture can help fibromyalgia patients by giving them acupuncture treatment and seeing whether acupuncture helps enhance the effects of an opioid.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/31/2025
Locations: UCI Health Susan Samueli Integrative Health Institute, Irvine, California
Conditions: Fibromyalgia
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Auricular Neuromodulation in Veterans With Fibromyalgia
NCT06415591
Recruiting
PENFS (percutaneous electrical nerve field stimulation) is an FDA-cleared acupuncture-like therapy applied to the external ear targeting several cranial nerve branches including the auricular branch of the vagus nerve to improve pain, physical function, and reduce symptoms of opioid withdrawal. PENFS has been previously shown to provide improvements in fibromyalgia, a difficult to treat chronic pain syndrome, which correlate with changes observed using a special kind of MRI called resting state... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia
Conditions: Fibromyalgia
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Brief Pain Exposure Therapy (BPET) for Nociplastic Pain
NCT06208514
Recruiting
This study is intended to test whether a brief Zoom-based behavioral treatment can help adults with fibromyalgia (FM) and Lupus learn effective strategies for reducing pain, disability and other problems that can come with fibromyalgia and Lupus (such as depression or anxiety).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/12/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Fibromyalgia, Lupus Erythematosus, Systemic
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The Effects of Energy Healing in Fibromyalgia
NCT06552728
Recruiting
This study aims to study the clinical effects of Energy Healing using fMRI and determine its application to Fibromyalgia patients. We also want to find out how active Energy Healing compares to sham Energy Healing in terms of brain connectivity and pain interference scores.
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
01/09/2025
Locations: University of California at Irvine, Irvine, California
Conditions: Fibromyalgia
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Microcurrent for Fibromyalgia
NCT04949100
Recruiting
Explore the use of microcurrent therapy for fibromyalgia patients and evaluate its effect on generalized pain and quality of life. Determine if microcurrent therapy be effectively self-administered by the patient as an adjunct to medical pain management.
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
01/06/2025
Locations: Mike O'Callaghan Military Medical Center, Nellis Air Force Base, Nevada
Conditions: Fibromyalgia
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Fibromyalgia Sleep A to ZZZ Study
NCT06567886
Recruiting
This research study is testing whether changes in sleep timing and morning light therapy may have an impact on symptoms related to fibromyalgia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/03/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Fibromyalgia
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Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
NCT03759522
Recruiting
The primary objective of this study is to measure the concentration and the regional brain distribution of activated brain microglia/macrophages using the PET radiopharmaceutical \[F-18\]DPA-714 in individuals with chronic pain and fatigue suspected to be associated with neuroinflammation. The PET tracer \[F-18\]DPA-714 binds to the 18 kDa translocator protein (TSPO, also known as the peripheral benzodiazepine receptor) in the mitochondria of activated microglia/macrophages and provides a non-in... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/13/2024
Locations: University of Alabama at Birmingham Medical Center, Birmingham, Alabama
Conditions: Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
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