There are currently 71 active clinical trials seeking participants for Insomnia research studies. The states with the highest number of trials for Insomnia participants are California, Florida, Texas and Ohio.
Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans
NCT05724498
Recruiting
Insomnia is a common condition in Veterans, with prevalence rates as high as 53% among treatment-seeking Veterans. Chronic untreated insomnia is associated with increased risk for functional impairment, psychiatric illness, suicidal ideation, unhealthy lifestyles, and decreased quality of life. Cognitive-Behavioral Therapy for Insomnia (CBT-I) is recognized as the first-line treatment for insomnia. Despite its proven efficacy, CBT-I is not always readily provided and/or accessible to Veterans. T... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2025
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California +1 locations
Conditions: Insomnia
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mPATH for Low-income Older Adults
NCT05935241
Recruiting
Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults. The study aims to test the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in low-income older adults.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
04/09/2025
Locations: The Johns Hopkins University, School of Nursing, Baltimore, Maryland
Conditions: Sedentary Time, Insomnia, Cognitive Decline
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Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
NCT05516277
Recruiting
This pilot pre-post trial will address a gap in knowledge related to addressing modifiable risk factors for cardiometabolic disease through treating residual insomnia, sleep difficulties that remain after successful treatment of another condition, in the context of PTSD in understudied older adults. This study provides a non-medication treatment for PTSD called Cognitive Processing Therapy (CPT) followed by a non-medication sleep education and treatment program (Cognitive Behavioral Therapy for... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/09/2025
Locations: VA Greater Los Angeles Healthcare System, North Hills, California
Conditions: Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
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Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
NCT05390918
Recruiting
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change strategies for adolescents at risk of suicidal behavior who suffer from difficulties falling asleep, staying asleep, and/or insufficient sleep.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
03/18/2025
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Insomnia, Suicidal Ideation, Suicide, Attempted
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Forehead Temperature-Regulating Therapy for Insomnia in Adults with Tourette's Disorder
NCT05499741
Recruiting
The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder. This project will also examine the effects of the device on depression, anxiety, and daytime sleepiness, and explore its effects on tic severity.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
03/13/2025
Locations: Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California
Conditions: Tourette's Disorder, Insomnia
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CBT-I to Improve Functional Outcomes in Veterans With Psychosis
NCT04646200
Recruiting
The goal of this project is to examine the efficacy of Cognitive Behavioral Therapy for Insomnia (CBT-I) for improving sleep and related functional outcomes in Veterans with psychosis and insomnia.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/13/2025
Locations: Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland +1 locations
Conditions: Insomnia, Psychosis
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Training in Evidence-based Treatments in Psycho-Oncology
NCT05674357
Recruiting
The goal of this research study is to train psychotherapists to administer individualized evidence-based psychotherapies in a cancer care setting to participants with elevated levels of distress due to their illness and/or treatment. The intervention will mirror clinical care in psycho-oncology in which the therapist, collaboratively with their supervisor, will choose specific components of the following evidence-based treatments to administer based on the clinical presentation of the patient a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/13/2025
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Distress, Emotional, Depression, Anxiety, Fatigue, Pain, Insomnia
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
ALL
Ages:
Between 0 years and 20 years
Trial Updated:
03/11/2025
Locations: Phoenix Children's Hospital, Phoenix, Arizona +50 locations
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
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Sleep to Reduce Incident Depression Effectively in Peripartum
NCT06430333
Recruiting
Perinatal depression (PND) is the most common complication in pregnancy and postpartum, which increases risk for adverse perinatal outcomes such as preterm birth, maternal suicidal thoughts, and impaired mother-infant bonding. Insomnia often precedes PND cases and may serve as an entry point for interventions preventing PND. The proposed project is a large-scale clinical trial to test the effectiveness of a mindfulness-based sleep program designed for pregnant women to improve sleep and alleviat... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Henry Ford Medical Center, Novi, Michigan
Conditions: Insomnia, Depression
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Enhancing Hypnotic Medication Discontinuation in Primary Care
NCT06435520
Recruiting
Many individuals with insomnia seek treatment in primary care settings, where they often receive prescription hypnotic medications as their first and sometimes only treatment. However, extended use of these medications can lead to reliance and increased health risks, such as falls and cognitive impairments. While evidence-based approaches like physician-supervised medication tapering exist, they're not widely available in primary care. Most primary care providers are willing to explore non-drug... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
02/20/2025
Locations: National Jewish Health, Denver, Colorado
Conditions: Insomnia, Hypnotic Dependence
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Tart Cherry Juice for Sleep in Older Adults with Insomnia: a Pilot Study of Feasibility and Comprehensive Mechanisms
NCT06786494
Recruiting
The purpose of this research study is test if a study that asks older adults with sleep problems to consume tart cherry products is feasible and determine if it can change sleep patterns. This study is a total of 12 weeks. Participants will be asked to consume tart cherry juice for 4 weeks and the placebo juice for 4 weeks, while wearing a digital monitor that measures sleep. Blood (about 3 teaspoons) and urine (about 2 tablespoons) samples will be taken before and after consuming both juices to... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
02/19/2025
Locations: Hebrew Rehabilitation Center, Roslindale, Massachusetts
Conditions: Sleep Problems, Insomnia
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The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
NCT05780814
Recruiting
The investigators propose a randomized controlled clinical trial in 250 women with a history of early stage breast cancer who are overweight or obese with insomnia to test whether a brief, cognitive-behavioral intervention for insomnia (CBT-I) prior to behavioral weight loss (CBT-I+BWL) is superior to a sleep education control (EDU) condition followed by behavioral weight loss (EDU+BWL). The investigators will measure outcomes at baseline, 8 weeks (after completing CBT-I or EDU and prior to BWL)... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: Sibley Memorial Hospital, Washington, District of Columbia +3 locations
Conditions: Breast Cancer, Insomnia, Weight Gain
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