There are currently 68 active clinical trials seeking participants for Insomnia research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Ohio.
Solriamfetol and CBT-I in Patients With Insomnia Disorder
NCT05838430
Recruiting
Medication is FDA approved. The objective of this project is to test the efficacy of solriamfetol for treating insomnia (alone and in combination with Cognitive Behavioral Therapy for Insomnia [CBT-I]). Ultimately, this study will test whether wake extension (regardless of how it is achieved) will consolidate sleep and improve sleep continuity.
Gender:
All
Ages:
Between 25 years and 60 years
Trial Updated:
08/17/2023
Locations: University of Pennsylvania, Behavioral Sleep Medicine Program, Philadelphia, Pennsylvania
Conditions: Insomnia
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Treatments for Insomnia in Veterans With PTSD
NCT05194930
Recruiting
This randomized trial will compare a novel treatment, Acceptance of the Behavioral Changes to Treat Insomnia (ABC-I) to Cognitive Behavioral Therapy for Insomnia (CBT-I) among Veterans with comorbid Post-Traumatic Stress Disorder (PTSD) and insomnia disorder. ABC-I combines the behavioral components of CBT-I with components of another behavioral therapy (Acceptance and Commitment Therapy) and has been shown to improve treatment adherence. The study objectives are: 1) to evaluate the benefits of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: VA Greater Los Angeles Healthcare System, Sepulveda, CA, Sepulveda, California
Conditions: Insomnia, PTSD
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The Effect of Sleep Loss on Emotion Regulation
NCT05393830
Recruiting
The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control. The investigators will address and attempt to answer two questions. (i) How do three nights of reduced sleep or a diagnosis of Insomnia Disorder affect the processing and regulation of emotional information compared to typical, undisturbed sleep? (ii) What overlapping and distinct neural mec... Read More
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
07/25/2023
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Sleep, Insomnia, Sleep Deprivation
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Pimavanserin for Insomnia in Veterans With PTSD
NCT05441280
Recruiting
This is a preliminary randomized, double-blind, placebo-controlled trial comparing pimavanserin 34mg at bedtime vs. placebo for the treatment of insomnia associated with post-traumatic stress disorder.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
07/25/2023
Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
Conditions: Post-traumatic Stress Disorder, Insomnia
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mHealth for Breast Cancer Survivors With Insomnia
NCT05233800
Recruiting
The aim of this study is to determine the impact of the voice-activated smart speaker CBT-I components on insomnia symptoms among breast cancer survivors using a randomized clinical trial.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/14/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Breast Cancer Survivor, Insomnia
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Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use
NCT05814822
Recruiting
This study will compare the efficacy of telemedicine-delivered cognitive behavioral therapy for insomnia tailored for people using cannabis for sleep (CBTi-CB-TM) to telemedicine-delivered sleep hygiene education (SHE-TM) on sleep, cannabis use, and daytime functioning. We will also evaluate the effects of CBTi-CB-TM on fundamental sleep regulatory system - homeostatic sleep drive - and its association with clinical outcomes.
Gender:
All
Ages:
21 years and above
Trial Updated:
06/02/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Insomnia
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The Impact of Insomnia on Pain in HIV
NCT04298658
Recruiting
The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2) if weekly fluctuations in insomnia burden drive changes in inflammation, pain severity, and physical functioning in people living with HIV. This research could help confirm insomnia as a therapeutic... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/01/2023
Locations: UAB, Birmingham, Alabama
Conditions: HIV, Insomnia
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Study Watch Sleep Metric Performance Characterization Study
NCT05276362
Recruiting
This is a multi-center, single-arm, prospective performance evaluation study designed to assess performance of sleep metrics calculated from sensor data that is collected from two versions of the Verily Study Watch as compared to polysomnography.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/30/2023
Locations: SRI International, Menlo Park, California
Conditions: Sleep, Obstructive Sleep Apnea, Insomnia
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Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder
NCT05499741
Recruiting
The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder. This project will also examine the effects of the device on depression, anxiety, and daytime sleepiness, and explore its effects on tic severity.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
05/17/2023
Locations: Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California
Conditions: Tourette's Disorder, Insomnia
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Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans
NCT05724498
Recruiting
Insomnia is a common condition in Veterans, with prevalence rates as high as 53% among treatment-seeking Veterans. Chronic untreated insomnia is associated with increased risk for functional impairment, psychiatric illness, suicidal ideation, unhealthy lifestyles, and decreased quality of life. Cognitive-Behavioral Therapy for Insomnia (CBT-I) is recognized as the first-line treatment for insomnia. Despite its proven efficacy, CBT-I is not always readily provided and/or accessible to Veterans. T... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/04/2023
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California +1 locations
Conditions: Insomnia
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Digital CBT for Insomnia and Depression
NCT05456607
Recruiting
This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2023
Locations: University of Rochester Sleep Research Laboratory, Rochester, New York
Conditions: Depression, Insomnia
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Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
NCT05565833
Recruiting
This randomized controlled trial will evaluate the impact of an Internet-delivered cognitive behavioral therapy for insomnia (CBT-I) intervention on sleep and the extent to which it contributes to cognitive health in individuals with mild cognitive impairment. Participants with insomnia who meet the study criteria for mild cognitive impairment will be recruited to determine the effects of the CBT-I intervention compared to a patient education condition on sleep and cognition. Internet-based recr... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
04/20/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Insomnia, Cognitive Dysfunction, Mild Cognitive Impairment, Sleep Initiation and Maintenance Disorders, Sleep Disorders, Intrinsic, Dyssomnias, Sleep Wake Disorders, Nervous System Diseases, Alzheimer Disease
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