There are currently 78 active clinical trials seeking participants for Insomnia research studies. The states with the highest number of trials for Insomnia participants are California, Florida, Texas and Ohio.
Investigating the Effects of Tube Feeds on Glycemia and Sleep in Adults With Cystic Fibrosis-Related Diabetes
NCT06700889
Recruiting
The goal of this at-home, remote study is to understand how tube feeding affects blood sugars and sleep in adults living with Cystic Fibrosis Related Diabetes (CFRD).
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
11/21/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Cystic Fibrosis Related Diabetes, Hyperglycaemia, Insomnia, Cardiometabolic Diseases, Circadian Rhythm Disorders
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Noradrenergic Dysregulation, Sleep and Cognition in Older Adults with Insomnia
NCT06694441
Recruiting
This study investigates the relationship between the noradrenergic (NA) system, sleep quality, and cognitive function in older adults with insomnia - a population at elevated risk for Alzheimer's disease-related dementias (ADRD) - compared to age and sex matched controls with normal sleep. The study characterizes NA function through multiple approaches: measuring 24-hour plasma levels of norepinephrine (NE) and its brain metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG); evaluating central NA sy... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
11/18/2024
Locations: Northwestern University Feinberg School of Medicine, Center for Circadian and Sleep Medicine, Chicago, Illinois
Conditions: Insomnia
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Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
NCT06580561
Recruiting
This research will compare the effectiveness of a remotely delivered personalized exercise coaching plus an evidence-based sleep improvement intervention to remotely delivered personalized exercise coaching alone for knee osteoarthritis pain. The study team hypothesize that the combined intervention will result in greater improvements in patient-reported pain intensity, recorded with real-time data capture, than remotely delivered exercise coaching alone.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
11/05/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Knee Osteoarthritis, Insomnia
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eHealth Insomnia Intervention for Adult Survivors of Childhood Cancer
NCT04317742
Recruiting
There is evidence that survivors of childhood cancer have a high prevalence of poor sleep, including symptoms of insomnia. Insomnia is highly comorbid and has been associated with impaired cognitive performance, a range of psychiatric disorders, cardiovascular disease, and reduced quality of life. However, we still lack knowledge about the direct impact of available internet-based insomnia treatment programs for survivors of childhood cancer experiencing insomnia, in addition to how improving in... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/04/2024
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee
Conditions: Childhood Cancer, Insomnia, Neurocognitive Impairment, Survivorship, Late Effect, Sleep
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Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
NCT06375265
Recruiting
The Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST) is a pilot randomized, controlled, singled-blinded (participant) trial in major orthopedic joint surgery patients that will build on a previously clinically tested cognitive behavioral therapy for insomnia (CBT-I) mobile application paired with a wearable device (wrist actigraphy).
Gender:
ALL
Ages:
65 years and above
Trial Updated:
11/04/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Insomnia, Postoperative Delirium, Delayed Neurocognitive Recovery, Postoperative Neurocognitive Disorder
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A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors
NCT06392789
Recruiting
This clinical trial evaluates the effect of conversational agent, Cecebot, on improving insomnia in stage I-III breast cancer survivors. Sleep disturbance ranks among the top concerns reported by breast cancer survivors and is associated with poor quality of life. Many breast cancer survivors also have decreased physical activity, which may also have a negative impact on sleep and quality of life. Cognitive behavioral therapy for insomnia (CBTi) and physical activity interventions have individua... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/31/2024
Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Insomnia
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Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
NCT06434571
Recruiting
The objective of this RCT is to assess the efficacy of one-on-one telehealth CBT-I (tCBT-I) compared to web-based CBT-I (wCBT-I) and treatment as usual (TAU) to improve sleep outcomes (Aim 1), fatigue and quality of life (Aim 2), and promote neuroprotection (Exploratory Aim 3), and to explore the characteristics of participants that predict improvement in sleep outcomes (Exploratory Aim 4). Reassessment of outcomes will be completed after the 6-week intervention and 6 months following completion... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/15/2024
Locations: University of Kansas Medical Center- Sleep, Health and Wellness Laboratory, Kansas City, Kansas
Conditions: Multiple Sclerosis, Insomnia
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Sleep Mechanisms of Regulating Emotions
NCT06373718
Recruiting
This project is the second phase of a two-phased project investigating the impact of a proven sleep intervention, Cognitive Behavioral Therapy for Insomnia (CBT-I) on engagement of the emotion regulation brain network as a putative mechanistic target.
Gender:
ALL
Ages:
Between 25 years and 60 years
Trial Updated:
10/11/2024
Locations: Stanford University, Palo Alto, California
Conditions: Insomnia, Depression
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Solriamfetol and CBT-I in Patients With Insomnia Disorder
NCT05838430
Recruiting
Medication is FDA approved. The objective of this project is to test the efficacy of solriamfetol for treating insomnia (alone and in combination with Cognitive Behavioral Therapy for Insomnia \[CBT-I\]). Ultimately, this study will test whether wake extension (regardless of how it is achieved) will consolidate sleep and improve sleep continuity.
Gender:
ALL
Ages:
Between 25 years and 60 years
Trial Updated:
10/01/2024
Locations: University of Pennsylvania, Behavioral Sleep Medicine Program, Philadelphia, Pennsylvania
Conditions: Insomnia
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RISE: A Remote Study of Insomnia Treatment in Crohn's Disease
NCT05956158
Recruiting
The purpose of this study is to assess whether the investigators can treat insomnia in people with Crohn's disease, and if insomnia treatment can make other things better, like pain or inflammation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Insomnia, Crohn Disease
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Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors
NCT06162663
Recruiting
Investigators propose a double-blind, placebo-controlled trial evaluating the use of the use of Suvorexant in breast cancer survivors on selective estrogen receptor modulators or aromatase inhibitors with sleep disturbance to assess the impact on insomnia symptoms and quality of life. Breast cancer survivors have an increased risk of insomnia for which Suvorexant has the has the potential ability to impact to improve sleep related outcomes and cancer survivorship outcomes. Breast cancer survivor... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: MUSC Department of Family Medicine, Charleston, South Carolina
Conditions: Breast Cancer, Insomnia
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Enhancing Digital CBT-I to Improve Adherence and Reduce Disparities
NCT05182372
Recruiting
The primary objective of this research study is to increase adherence of Digital Cognitive Behavioral Treatment for Insomnia (dCBT-I). Additionally, this study will examine behavioral, physical, and sociocultural factors associated with treatment engagement.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/17/2024
Locations: Henry Ford Columbus Medical Center, Novi, Michigan
Conditions: Insomnia
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