There are currently 129 active clinical trials seeking participants for Multiple Sclerosis research studies. The states with the highest number of trials for Multiple Sclerosis participants are Florida, New York, California and Ohio.
IL-11 in the Development of Multiple Sclerosis
NCT03735823
Recruiting
Since the last submission, the investigator have further characterized the potential of IL--11 to induce encephalitogenic CD4+IL--17A+, IL--21+ and GM--CSF+ cells, which upon passive transfer induced severe RREAE with IL--17A+CCR6+ CD4+ cell, neutrophil, CD8+ and B--cell accumulation within the CNS (manuscript submitted for publication). These findings confirmed our hypothesis and further characterization of the IL--11--induced encephalitogenic CD4+ cells will be performed as planned in the gran... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/03/2022
Locations: Thomas Jefferson University, Philadelphia, Pennsylvania
Conditions: Multiple Sclerosis
Register for Updates
Outcomes Mandate National Integration With Cannabis as Medicine
NCT03944447
Recruiting
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/29/2022
Locations: OMNI Medical Services, Boca Raton, Florida +16 locations
Conditions: Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma, Fibromyalgia, Seizures, Hepatitis C, Cancer, Crohn Disease, HIV/AIDS, Multiple Sclerosis, Traumatic Brain Injury, Sickle Cell Disease, Post Traumatic Stress Disorder, Tourette Syndrome, Ulcerative Colitis, Glaucoma, Epilepsy, Inflammatory Bowel Diseases, Parkinson Disease, Amyotrophic Lateral Sclerosis, Chronic Traumatic Encephalopathy, Anxiety, Depression, Insomnia, Autism, Opioid-use Disorder, Bipolar Disorder, Covid19, SARS-CoV Infection, COVID-19, Corona Virus Infection, Coronavirus
Register for Updates
Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training
NCT03057652
Recruiting
The purpose of this study is to develop an algorithmic-based evaluation and treatment approach for wearable robotic exoskeleton (WRE) gait training for patients with neurological conditions.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/19/2022
Locations: TIRR Memorial Hermann, Houston, Texas
Conditions: Complete Spinal Cord Injury, Incomplete Spinal Cord Injury, Acquired Brain Injury, Multiple Sclerosis
Register for Updates
A Prospective Biomarker Study in Active SPMS Subjects Treated With Cladribine Tablets
NCT04550455
Recruiting
The purpose of this study is to explore the concept that biomarker sensitivity will detect activity in Multiple Sclerosis (MS) subjects and allow appropriate change in treatment to prevent dysfunction.
Gender:
All
Ages:
Between 21 years and 65 years
Trial Updated:
01/12/2022
Locations: Multiple Sclerosis Center of Northeastern New York, P.C., Latham, New York
Conditions: Multiple Sclerosis
Register for Updates
Novel Assessment of Synaptic Density in Progressive MS
NCT04634994
Recruiting
The investigators propose to use the novel SV2a-PET ligand, [F-18]SDM-8 to assess synaptic density in progressive MS (including primary progressive multiple sclerosis (PPMS) and secondary progressive multiple sclerosis (SPMS)) as compared to relapsing-remitting multiple sclerosis (RRMS) patients and healthy controls, given its improved imaging characteristics and potential for large scale applicability. The specific aims of the study are: Aim 1: To compare the cortical and subcortical grey mat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
07/20/2021
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Primary Progressive Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Relapsing Multiple Sclerosis, Multiple Sclerosis
Register for Updates
Home Based Infusions for Ocrelizumab
NCT04650321
Recruiting
The goal is to assess the safety and effectiveness of home ocrelizumab infusion.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/08/2021
Locations: Amerita, Centennial, Colorado
Conditions: Multiple Sclerosis
Register for Updates
Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-
NCT04843813
Recruiting
The central hypothesis is that lutein supplementation will improve MPOD and cognition. Accordingly, the specific aims are to 1) to determine the process feasibility associated with participating in 4-month lutein supplementation trial; and 2) to investigate the scientific feasibility of 4-month daily lutein supplementation on biological markers of lutein status and cognitive function among persons with MS.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
04/12/2021
Locations: University of Illinois at Urbana-Champaign, Urbana, Illinois
Conditions: Multiple Sclerosis
Register for Updates
Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals
NCT04503187
Recruiting
Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills post stroke. Thus, the overall purpose of this research project is to examine stroke survivors' capability of learning a novel leg task over 3 visits, 1-2 weeks apart. The capability of learning a new skill is then correlated with the individual's neurological functions (nerve activity and movement... Read More
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
08/03/2020
Locations: Texas Woman's University, Houston, Texas
Conditions: Stroke, Multiple Sclerosis
Register for Updates
Complementary and Alternative Care in Multiple Sclerosis
NCT01703429
Recruiting
This is a prospective, observational study designed to describe disease progression, symptom change, quality of life, diet and lifestyle habits, and frequency of adverse events among patients with multiple sclerosis (MS) who use complementary and alternative medicine (CAM). In addition to describing the patterns of CAM use, this study will also identify and describe the positive deviants, those individuals with the highest quality of life and least amount of disease activity. Positive deviants w... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
02/07/2020
Locations: Bastyr University Clinical Research Center, Kenmore, Washington
Conditions: Multiple Sclerosis
Register for Updates