There are currently 128 active clinical trials seeking participants for Multiple Sclerosis research studies. The states with the highest number of trials for Multiple Sclerosis participants are New York, Florida, California and Ohio.
Protective Stepping & MS
NCT03551665
Recruiting
Falls are common in Veterans with multiple sclerosis (MS), and current rehabilitation approaches to reduce falls are inadequate. Protective step training (in which a person is exposed to repeated "slips") is a promising tool to reduce falls in older adults. However, whether this approach is effective in people with MS is unknown. Investigating the effect of promising therapies, such as protective step training, will enhance our ability to treat Veterans with MS who are at risk for falls. Therefo... Read More
Gender:
All
Ages:
Between 20 years and 80 years
Trial Updated:
09/08/2023
Locations: Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona
Conditions: Multiple Sclerosis
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High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
NCT05951985
Recruiting
Individuals with and without neurologic diagnoses greatly benefit from participation in regular exercise but the majority are physically inactive. This is an issue for both them and their care partners as their health is often linked. This study aims to examine the long-term physical and psychosocial effects of structured, group-based, high intensity functional training (HIFT) exercise for people with neurologic diagnoses and their care partners.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/08/2023
Locations: Arkansas Colleges of Health Education, Fort Smith, Arkansas
Conditions: Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida, Stroke, Poliomyelitis, Multiple Sclerosis, Brain Injuries
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AIM's Writing for Healing: A Workshop for Individuals Living With Paralysis
NCT04721717
Recruiting
The UAB Institute for Arts In Medicine (AIM) is currently implementing an expressive emotional writing pilot project for adults with paralysis caused by neurological conditions such as traumatic head or spinal cord injury.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/27/2023
Locations: 354 School of Health Professions Building, Birmingham, Alabama
Conditions: Spinal Cord Injuries, Multiple Sclerosis, Transverse Myelitis, Amyotrophic Lateral Sclerosis
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Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
NCT05982925
Recruiting
In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclerosis (MS) and other inflammatory and autoimmune disorders affecting the CNS. Patients with these disorders, as well as healthy controls, will undergo baseline clinical evaluation and testing, bloodwork... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/08/2023
Locations: Mount Sinai Hospital, New York, New York
Conditions: Multiple Sclerosis, Neuromyelitis Optica, Demyelinating Autoimmune Diseases, CNS
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Meeting an Unmet Need in Multiple Sclerosis
NCT05953519
Recruiting
The primary objectives of this study is to examine the efficacy of the Unified Protocol in decreasing depression and anxiety among individuals with MS and the secondary outcomes (e.g., improved well-being, QOL, coping, etc.) that may occur in tandem.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/12/2023
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Multiple Sclerosis
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Entire-body PET Scans for Multiple Sclerosis
NCT04390009
Recruiting
To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation, monitoring and measurement of both peripheral and central demyelination in multiple sclerosis (MS) patients.
Gender:
All
Ages:
Between 25 years and 55 years
Trial Updated:
07/11/2023
Locations: Brain Health Alliance, Ladera Ranch, California
Conditions: Multiple Sclerosis
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Autoimmune Intervention Mastery Course Study
NCT05057676
Recruiting
The goal of this project is to critically evaluate the effectiveness of using an online program to improve diet and self-care in patients with multiple sclerosis (MS), clinically isolated syndrome (CIS), fibromyalgia, and post acute sequela of covid
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
07/10/2023
Locations: Univeristy of Iowa, Iowa City, Iowa
Conditions: Multiple Sclerosis, Clinically Isolated Syndrome, Fibromyalgia, Post Acute Sequelae of COVID-19
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Exercise Training, Cognition, and Mobility in Older Adults With Multiple Sclerosis
NCT05930821
Recruiting
The overall objective of the proposed randomized controlled (RCT) is to determine the feasibility and efficacy of a 16-week theory-based, remotely-delivered, combined exercise (aerobic and resistance) training intervention for improving cognitive and physical function in older adults (50+ years) with multiple sclerosis (MS) who have mild-to-moderate cognitive and walking impairment. Participants (N=50) will be randomly assigned into exercise training (combined aerobic and resistance exercise) co... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
07/05/2023
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Older Adults, Multiple Sclerosis, Cognitive Impairment, Walking Impairment
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Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS
NCT05500963
Recruiting
The objective of the randomized, sham-controlled trial will be to evaluate the effectiveness of treatment with transcutaneous electrical nerve stimulation (TENS) at reducing the level of fatigue experienced by people with MS.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/25/2023
Locations: University of Colorado, Boulder, Colorado
Conditions: Multiple Sclerosis
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Aerobic Exercise for Remyelination in Multiple Sclerosis
NCT04539002
Recruiting
This is a clinical trial to determine the feasibility of a stationary aerobic cycling intervention and explore if aerobic exercise independently promotes remyelination in people with multiple sclerosis (MS).
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
04/25/2023
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Multiple Sclerosis, Sclerosis, Demyelinating Diseases, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Demyelinating Autoimmune Diseases, CNS, Exercise
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Gut Microbiome and Depression
NCT05808101
Recruiting
The purpose of this project is to determine if specific gut microbiome or gut-derived metabolites are associated with depression in patients with Multiple Sclerosis (pwMS). Mechanistically, the investigators further hypothesize that depression in pwMS is related to decreased abundance of gut bacteria with GABA-producing activities and/or with anti-inflammatory properties. To determine if the presence of depression in pwMS is associated with specific gut microbiome, gut-derived metabolites or per... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2023
Locations: Washington University in St Louis, Saint Louis, Missouri
Conditions: Multiple Sclerosis, Depression
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PTNS for Female Patients Suffering From Multiple Sclerosis
NCT05422625
Recruiting
This is a pilot, single blind, randomized, sham-controlled trial to assess the benefit of PTNS in treating OAB symptoms in MS patients. The data generated by this study would provide support for a future multi-institutional, randomized prospective trial.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/06/2023
Locations: Beaumont Hospital - Royal Oak, Royal Oak, Michigan
Conditions: Multiple Sclerosis, Overactive Bladder
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