There are currently 128 active clinical trials seeking participants for Multiple Sclerosis research studies. The states with the highest number of trials for Multiple Sclerosis participants are New York, Florida, California and Ohio.
Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis
NCT06233370
Recruiting
The project will involve a within-subjects, repeated-measures research design. Participants will initially be screened for relevant inclusion/exclusion criteria for maximizing safety of participating in an exercise study. If a participant meets those inclusion/exclusion criteria, they will visit Kessler Foundation three times. The first visit will involve a baseline session where participants will complete several cognitive tests. This will be followed by a training session, where participants w... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/03/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Multiple Sclerosis
Register for Updates
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
NCT04855825
Recruiting
The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton device (Ekso-GT), to improve learning and memory, and gait therapy in persons with walking disability due to Multiple Sclerosis. The study will evaluate the mobility, learning and memory, and walking abilities of individuals with multiple sclerosis who went through the traditional as compared to others who used the robotic exoskeleton as part of their therapy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/01/2024
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Multiple Sclerosis, Gait Disorders, Neurologic, Motility Disorder, Cognitive Impairment
Register for Updates
Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis
NCT06329414
Recruiting
The goal of this single-arm, observational pilot study is to learn about the safety, feasibility, preliminary efficacy of TMS for the treatment of depression in people with MS. Participants will receive outpatient TMS treatment over the course of 5-6 weeks. Participants will complete validated questionnaires and exams before, during, and after treatment.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/22/2024
Locations: University of Utah Health, Salt Lake City, Utah
Conditions: Multiple Sclerosis, Major Depressive Disorder, Treatment Resistant Depression
Register for Updates
Intestinal Immunity in Neurologic Disease
NCT06329453
Recruiting
The purpose of this study is to ascertain the functional profiles of the immune cells within the gastrointestinal tract and to determine how these cells contribute to autoimmune and neurologic diseases.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/22/2024
Locations: Yale MS Clinic, North Haven, Connecticut
Conditions: Multiple Sclerosis, Parkinson Disease, REM Sleep Behavior Disorder
Register for Updates
NYSCF Scientific Discovery Biobank
NCT06203106
Recruiting
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and store the samples for future use. Through this research, researchers hope to identify future treatments or even cures for the major diseases of our time.
Gender:
All
Ages:
30 days and above
Trial Updated:
03/21/2024
Locations: New York Stem Cell Foundation Research Institute, New York, New York
Conditions: ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Batten Disease, Corticobasal Degeneration, Dementia, Frontotemporal Dementia, Huntington Disease, Lewy Body Disease, Multiple Sclerosis, Multiple System Atrophy, Parkinson Disease, Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, INAD, Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Macular Degeneration, Ovarian Cancer, Cervical Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer, PTSD, Post Traumatic Stress Disorder
Register for Updates
Vancomycin Study in Multiple Sclerosis (MS)
NCT05539729
Recruiting
The overall goal of this study is to elucidate a mechanism by which vancomycin modulates the gut-brain axis in multiple sclerosis (MS). The gut microbiome plays an important role in autoimmunity, including MS. However, the identity of gut microbes modulating neuroinflammation in MS and their mechanisms of action remain obscure. Hence, here the research team proposes to investigate the effects of vancomycin on the gut microbiota composition, peripheral immune function, and brain MRI lesions in MS... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
03/21/2024
Locations: Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Sinai, New York, New York
Conditions: Multiple Sclerosis
Register for Updates
ECoG BMI for Motor and Speech Control
NCT03698149
Recruiting
Test the feasibility of using electrocorticography (ECoG) signals to control complex devices for motor and speech control in adults severely affected by neurological disorders.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/17/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: ALS, SCI - Spinal Cord Injury, Stroke, Multiple Sclerosis, Muscular Dystrophies
Register for Updates
The MS-LINK™ Outcomes Study
NCT04735406
Recruiting
The Multiple Sclerosis (MS) Leadership and Innovation Network (MS-LINK™) is comprised of networks working cooperatively to advance Multiple Sclerosis (MS) science and improve MS participant outcomes. In this study participants will be followed from the time of consent through the lifetime of the study (currently 3 years), unless the participant chooses to withdraw from the study. Collection of participant's medical history, including MS and treatment history, will be automated through extraction... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Alabama Neurology Associates, Birmingham, Alabama +8 locations
Conditions: Multiple Sclerosis
Register for Updates
A Novel Combinatory Approach to Maximize Functional Recovery of Learning and Memory in Multiple Sclerosis
NCT06197685
Recruiting
The goal of this novel study is to compare the effect of a combined cognitive rehabilitation and exercise approach on new learning and memory (NLM) in persons with multiple sclerosis (pwMS) and mobility disability.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/15/2024
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Multiple Sclerosis
Register for Updates
MS-DETECT: Early Detection of Multiple Sclerosis Progression With MSCopilot® Detect
NCT05816122
Recruiting
The study aims to evaluate MSCopilot® Detect, a smartphone application for at-home monitoring of patients with Multiple Sclerosis (MS). The primary objective is to enhance and standardize remote monitoring of MS patients to accurately assess disease progression caused by either Relapse Activity Worsening (RAW) or Progression Independent of Relapses (PIRA). The study also aims to assess the safety, usability, and satisfaction of the solution. A secondary objective is to determine MSCopilot® Det... Read More
Gender:
All
Ages:
Between 30 years and 65 years
Trial Updated:
03/14/2024
Locations: Joash Lazarus Sr., Atlanta, Georgia +31 locations
Conditions: Multiple Sclerosis
Register for Updates
The Gilenya Pregnancy Registry
NCT01285479
Recruiting
The purpose of the Multi-National Gilenya Pregnancy Exposure Registry in Multiple Sclerosis (MS) is to continuously monitor, evaluate, and assess for major and minor teratogenic effects in the offspring of women exposed to fingolimod before (up to 8 weeks before last menstrual period (LMP)) and during pregnancy in routine clinical practice. The overall aim is to collect and evaluate data on maternal, fetal, and infant outcomes and compare it with reference populations.
Gender:
Female
Ages:
All
Trial Updated:
03/13/2024
Locations: Novartis Investigative Site, Fort Lauderdale, Florida +63 locations
Conditions: Multiple Sclerosis
Register for Updates
Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
NCT05848323
Recruiting
This prospective case series will use mixed methods to examine the feasibility, acceptability, and initial effects of three telehealth cognitive behavioral therapy components (relaxation training, behavioral activation, cognitive therapy) for fatigue in people with multiple sclerosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Multiple Sclerosis Center at UW Medical Center - Northwest, Seattle, Washington
Conditions: Multiple Sclerosis, Fatigue
Register for Updates