There are currently 127 active clinical trials seeking participants for Multiple Sclerosis research studies. The states with the highest number of trials for Autism participants are New York, Florida, California and Ohio.
The Gilenya Pregnancy Registry
NCT01285479
Recruiting
The purpose of the Multi-National Gilenya Pregnancy Exposure Registry in Multiple Sclerosis (MS) is to continuously monitor, evaluate, and assess for major and minor teratogenic effects in the offspring of women exposed to fingolimod before (up to 8 weeks before last menstrual period (LMP)) and during pregnancy in routine clinical practice. The overall aim is to collect and evaluate data on maternal, fetal, and infant outcomes and compare it with reference populations.
Gender:
Female
Ages:
All
Trial Updated:
03/13/2024
Locations: Novartis Investigative Site, Fort Lauderdale, Florida +63 locations
Conditions: Multiple Sclerosis
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Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
NCT05848323
Recruiting
This prospective case series will use mixed methods to examine the feasibility, acceptability, and initial effects of three telehealth cognitive behavioral therapy components (relaxation training, behavioral activation, cognitive therapy) for fatigue in people with multiple sclerosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Multiple Sclerosis Center at UW Medical Center - Northwest, Seattle, Washington
Conditions: Multiple Sclerosis, Fatigue
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Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS
NCT03983681
Recruiting
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons with Multiple Sclerosis.
Gender:
All
Ages:
Between 18 years and 59 years
Trial Updated:
02/28/2024
Locations: Kessler Foundation, East Hanover, New Jersey +1 locations
Conditions: Multiple Sclerosis
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Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis
NCT06264336
Recruiting
Nearly 1 million individuals in the United States have multiple sclerosis, which causes fatigue and problems with walking. Fatigue and walking problems are poorly treated, but exercise training, particularly high-intensity walking exercise, may help. This provide insight into whether high-intensity walking exercise can improve fatigue and walking problems in people with multiple sclerosis, which could improve quality of life and reduce economic burden.
Gender:
All
Ages:
21 years and above
Trial Updated:
02/26/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Multiple Sclerosis
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A Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring
NCT05170126
Recruiting
The purpose of this study is to provide information on maternal, fetal, and infant outcomes following exposure of ozanimod during pregnancy so that participants and physicians can weigh the benefits and risks of exposure to the pharmaceutical during pregnancy and make informed treatment decisions.
Gender:
Female
Ages:
All
Trial Updated:
02/26/2024
Locations: Evidera, Bethesda, Maryland +1 locations
Conditions: Multiple Sclerosis
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Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis
NCT05285891
Recruiting
This study is a prospective, multi-center, randomized, double blinded, placebo-controlled study of OCR treatment-discontinuation in patients with early RMS. All eligible participants will be initiated on OCR using the standard approved administration schedule of two 300 mg infusions separated by 14 days (i.e., Days 0 and 14) for a total of 600 mg, followed by 600 mg infusions at Month 6 and Month 12. At Month 12, participants will be randomized (1:1:1) to one of three Arms with randomized treatm... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/20/2024
Locations: Yale School of Medicine, New Haven, Connecticut +11 locations
Conditions: Multiple Sclerosis
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A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis
NCT05865405
Recruiting
The researchers want to find out if an electronic application called MS CATCH can enhance patients' and doctors' experiences during and in between clinical visits. MS CATCH is a smartphone-based tool which allows patients to enter their mood related symptoms at regular intervals, which is then available to their Neurologist in their electronic medical record. The neurologist is also able to view additional information from their medical record, and receives alerts for changes reported by the pat... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/16/2024
Locations: Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California
Conditions: Multiple Sclerosis, MS, Depression
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Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.
NCT03807973
Recruiting
This study will use brain Positron Emission Tomography/ Magnetic Resonance Imaging (PET/MRI) and an investigational radioactive drug called [Zr-89]oxine to track the location of white blood cells (also called leukocytes) in the body. PET/MRI will be used to visualize labeled white blood cells and determine if they enter the central nervous system in conditions associated with brain inflammation (also called neuroinflammation). By better understanding the role of neuroinflammation in fibromyalgia... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/13/2024
Locations: UAB, Birmingham, Alabama
Conditions: Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
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HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH) - Multiple Sclerosis (MS)
NCT06145737
Recruiting
The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with multiple sclerosis (MS). The main questions it aims to answer are: Can the current HOBSCOTCH program be adapted for people with MS? Will people with MS experience improved quality of life similar to that found in people with epilepsy after participating in the HOBSCOTCH program? Participants will be asked to: attend nin... Read More
Gender:
All
Ages:
Between 20 years and 65 years
Trial Updated:
02/13/2024
Locations: Dartmouth-Hitchcock, Lebanon, New Hampshire
Conditions: Multiple Sclerosis, Cognitive Dysfunction, Memory Disorders
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Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)
NCT06191380
Recruiting
To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/13/2024
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Multiple Sclerosis
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Examining a Wheelchair Exercise-training Intervention for Persons With Multiple Sclerosis
NCT05888727
Recruiting
The goal of this randomized controlled clinical trial is to examine the feasibility and initial efficacy of undertaking and delivering a novel, stakeholder-informed exercise training program for wheelchair users with multiple sclerosis. The main questions it aims to answer are: Is the study feasible as measured by participant recruitment (24 participants total), retention (80%), and safety (adverse events)? Is the study acceptable as measured by participant satisfaction and perceptions using an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Multiple Sclerosis
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MS-ResearchBiomarkerS
NCT05204459
Recruiting
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information from visual assessment, blood markers, as well as historical and ongoing longitudinal MRIs of the brain, orbit (the part of the skull where eyes are located), and/or spinal cord can predict changes in quantitative disability measures related to MSRD and neurological disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive, Clinically Isolated Syndrome, Radiologically Isolated Syndrome, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Neurologic Autoimmune Disease, Neurologic Disorder, Healthy Aging
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