Connecticut is currently home to 1243 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Bridgeport Hospital, Bridgeport, Connecticut
Conditions: NASH - Nonalcoholic Steatohepatitis
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BlueWind RENOVA iStim™ System for the Treatment of OAB
NCT03596671
Recruiting
The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
12/29/2023
Locations: Norwalk Urology, Norwalk, Connecticut
Conditions: Treatment of Patients Suffering From Overactive Bladder (OAB)
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Etomidate Versus Propofol in CABG Surgery
NCT06068764
Recruiting
The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this study is to determine whether patients receiving etomidate or propofol exhibit similar requirements for vasopressor or ionotropic agents during both the intraoperative and postoperative periods. To a... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/27/2023
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Coronary Artery Disease
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TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery
NCT04197687
Recruiting
This phase II trial studies how well TPIV100 and sargramostim work in treating patients with HER2 positive, stage II-III breast cancer that has residual disease after chemotherapy prior to surgery. It also studies why some HER2 positive breast cancer patients respond better to chemotherapy in combination with trastuzumab and pertuzumab. TPIV100 is a type of vaccine made from HER2 peptide that may help the body build an effective immune response to kill tumor cells that express HER2. Sargramostim... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Middlesex Hospital, Middletown, Connecticut
Conditions: Breast Adenocarcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7
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Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
NCT05996133
Recruiting
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method of postoperative pain control in patients undergoing posterior cervical spine fusion surgery. The main question it aims to answer is if the MCP block group will have reduced maximum pain scores during the first 24 postoperative hours compared to the sham block group. Participants will receive preoperative bilateral MCP... Read More
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
12/13/2023
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Cervical Spine Fusion
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Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants
NCT05865041
Recruiting
The main purpose of this study is to measure the efficacy of farudodstat compared to placebo at Week 12 from the treatment start, in adult participants with Alopecia Areata (AA) with 30% or greater scalp hair loss.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2023
Locations: 1 Site, New Haven, Connecticut
Conditions: Alopecia Areata
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Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm
NCT05214131
Recruiting
Identify the dry night rate in patients using the GoGoband® nocturnal enuresis device vs a standard Pflaundler bedwetting alarm.
Gender:
ALL
Ages:
Between 6 years and 21 years
Trial Updated:
12/11/2023
Locations: Yale New Haven Health, New Haven, Connecticut
Conditions: Bedwetting, Nocturnal Enuresis, Urinary Incontinence
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Study of Circulating Monocytes in Patients With Ischemic Vascular Disease
NCT04321512
Recruiting
The purpose of this research study is to discover the functions of circulating white blood cells, called monocytes, and associated circulating substances in heart attack and ischemic stroke patients. Ischemic Strokes (clots) occur as a result of an obstruction within a blood vessel supplying blood to the brain. A type of monocyte carrying a surface marker called "P2X4" helps the immune system sense and respond to danger signals from the body such as heart muscle and brain tissue injuries. The r... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Myocardial Infarction, Stroke, Ischemic, Ischemia
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Circulating Markers for Ischemic Heart Disease
NCT00762333
Recruiting
The purpose of this research is to determine if two proteins in the blood are increased during acute myocardial infarction and whether their levels are higher in those who develop heart failure than those who do not. These two proteins are produced and potentially released when the heart muscle is damaged. They may then be released into the blood and be detected by standard method in the research laboratory. At this time, detection of an increase in these proteins in the blood is not known to be... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Myocardial Infarction, Ischemia, Congestive Heart Failure
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Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
NCT00762008
Recruiting
The purpose of this research is to determine if two proteins in the blood are increased during acute heart failure. These two proteins are produced when the heart becomes dysfunctional and unable to contract normally. They may then be released into the blood and be detected by standard method in the research laboratory. Thus, the purpose of this study is to determine the relation between the change of these two proteins in the blood and the occurrence of acute heart failure. At this time, detect... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2023
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Acute Decompensated Heart Failure, Heart Failure
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Treatment With Endovascular Intervention for STroke Patients With Existing Disability
NCT05911568
Recruiting
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Hartford Health Hospital, Hartford, Connecticut
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic
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Characterizing Orthodontic Tooth Movement With Photographic Scans
NCT05780788
Recruiting
Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans. Canine retraction over the course of 1 orthodontic visit will be measured.
Gender:
ALL
Ages:
11 years and above
Trial Updated:
11/27/2023
Locations: UConn Health, Farmington, Connecticut
Conditions: Canine Retraction
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