Connecticut is currently home to 1249 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
SpermQT Prospective Observational Trial
Recruiting
The goal of the study is to validate the ability of the Epigenetic Sperm Quality Test (SpermQT) to assess a man's sperm quality and corresponding success of infertility treatments.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
02/19/2024
Locations: Yale Medicine, Orange, Connecticut
Conditions: Male Infertility
Alcohol-ROC-Training
Recruiting
The goal of the proposed study is to examine whether brief training in regulation of craving (ROC-T) affects alcohol drinking. The study will consist of a basic screening (phone and online), and in person visit to determine eligibility and conduct pre-intervention baseline assessments, 1-4 training (ROC-T) visits, a post-intervention assessment visit, and 1-2 phone/online follow up assessments.The two active conditions of ROC-T are based on cognitive-behavioral treatments (CBT) and mindfulness-b... Read More
Gender:
ALL
Ages:
Between 18 years and 26 years
Trial Updated:
02/07/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors
Recruiting
Subjects will undergo baseline evaluation and an assessment of extent of disease. Subjects in Part 1 (Dose Escalation) will receive escalating doses of CB-03-10 based on a modified Fibonacci schema using a standard oncology 3+3 study design to define an MTD and a RP2D. Plasma PK samples will be collected at predetermined timepoints for all subjects. Subjects in Part 2 (Dose Expansion) of the study will receive CB-03-10 at the RP2D determined in the Part 1 of the study. The indications included... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Yale Cancer Center, New Haven, Connecticut
Conditions: Advanced Refractory Solid Tumors, Subjects Considered Likely to Respond to CB-03-10
Posture Correction in Cubital Tunnel Syndrome
Recruiting
The primary objective of this study is to determine whether the UpRight Go posture trainer reduces the symptoms of cubital tunnel syndrome in patients who have not had corrective surgery, as determined by improvements in VAS scores for pain, numbness, and weakness.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Cubital Tunnel Syndrome
Mind Body Program Vascular
Recruiting
The purpose of the current study is to conduct a proof-of-concept test regarding the delivery of a Mind Body Program for vascular disease, focusing on support for depression, stress, and adherence, as part of patients' chronic disease management for peripheral artery disease (PAD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/25/2024
Locations: Yale New Haven Health Hospital, New Haven, Connecticut
Conditions: Peripheral Arterial Disease, Peripheral Vascular Diseases
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Bridgeport Hospital, Bridgeport, Connecticut
Conditions: NASH - Nonalcoholic Steatohepatitis
BlueWind RENOVA iStim™ System for the Treatment of OAB
Recruiting
The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
12/29/2023
Locations: Norwalk Urology, Norwalk, Connecticut
Conditions: Treatment of Patients Suffering From Overactive Bladder (OAB)
Etomidate Versus Propofol in CABG Surgery
Recruiting
The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this study is to determine whether patients receiving etomidate or propofol exhibit similar requirements for vasopressor or ionotropic agents during both the intraoperative and postoperative periods. To a... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/27/2023
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Coronary Artery Disease
TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery
Recruiting
This phase II trial studies how well TPIV100 and sargramostim work in treating patients with HER2 positive, stage II-III breast cancer that has residual disease after chemotherapy prior to surgery. It also studies why some HER2 positive breast cancer patients respond better to chemotherapy in combination with trastuzumab and pertuzumab. TPIV100 is a type of vaccine made from HER2 peptide that may help the body build an effective immune response to kill tumor cells that express HER2. Sargramostim... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Middlesex Hospital, Middletown, Connecticut
Conditions: Breast Adenocarcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7
Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
Recruiting
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method of postoperative pain control in patients undergoing posterior cervical spine fusion surgery. The main question it aims to answer is if the MCP block group will have reduced maximum pain scores during the first 24 postoperative hours compared to the sham block group. Participants will receive preoperative bilateral MCP... Read More
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
12/13/2023
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Cervical Spine Fusion
Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants
Recruiting
The main purpose of this study is to measure the efficacy of farudodstat compared to placebo at Week 12 from the treatment start, in adult participants with Alopecia Areata (AA) with 30% or greater scalp hair loss.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2023
Locations: 1 Site, New Haven, Connecticut
Conditions: Alopecia Areata
Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm
Recruiting
Identify the dry night rate in patients using the GoGoband® nocturnal enuresis device vs a standard Pflaundler bedwetting alarm.
Gender:
ALL
Ages:
Between 6 years and 21 years
Trial Updated:
12/11/2023
Locations: Yale New Haven Health, New Haven, Connecticut
Conditions: Bedwetting, Nocturnal Enuresis, Urinary Incontinence