Connecticut is currently home to 1213 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
NCT05313165
Recruiting
A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/31/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Register for Updates
OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
NCT05911646
Recruiting
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA). Our hypothesis is that in children with mild OSA there is significant conflict with parental decision-making; in the absence of significant sleep apnea, there is limited research regarding comparative efficacy of various treatment options. The impact of a QOL questionnaire can be a significant deciding factor and may... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
05/30/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Apnea, Obstructive Sleep, Obstructive Sleep Apnea
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Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy
NCT05730309
Recruiting
The objective of the proposed project is to quantify the prevalence and disparities of undiagnosed left ventricular hypertrophy (LVH) in Emergency Department (ED) patients with persistently elevated asymptomatic BP, and to measure the effect of disclosure, education, and expedited referral on 3-month outpatient follow-up and treatment rates for ED patients with newly diagnosed LVH by POCUS. Additionally, investigators will create a database of annotated clips for future development of a machine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Left Ventricular Hypertrophy
Register for Updates
The Study of NC318 Alone or in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer
NCT04699123
Recruiting
This is a phase 2 study to investigate NC318 alone or in combination with Pembrolizumab in patients with advanced non-small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Advanced Non-small Cell Lung Cancer
Register for Updates
Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease
NCT04291612
Recruiting
This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Hartford Healthcare Cancer Institute @ Hartford Hospital, Hartford, Connecticut
Conditions: Endometrial Cancer, Endometrioid Adenocarcinoma, Endometrial Cancer Stage I
Register for Updates
Sex Differences in E-cig Perception: Study 1
NCT05432830
Recruiting
The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.
Gender:
ALL
Ages:
Between 21 years and 44 years
Trial Updated:
05/22/2024
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
Register for Updates
MR-US Image Fusion Targeted Biopsy for Single-cell Prostate Cancer Research
NCT02313623
Recruiting
The investigators hypothesize that this single-cell analysis can be used to evaluate prostate needle-core biopsies prospectively even in non-homogenous samples by providing profiles of proteomic and phenotypic signatures. These profiles will in turn enable better predictions of the malignant progression of prostate cancers in the settings of current clinical practice.
Gender:
MALE
Ages:
Between 18 years and 80 years
Trial Updated:
05/22/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Prostate Cancer
Register for Updates
Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder
NCT06142955
Recruiting
This study will assess clinical and behavioral measures along with electroencephalogram (EEG), event-related potentials (ERPS), and eye-tracking (ET) prior to and following a single intermittent Theta Burst Stimulation (iTBS) session to provide preliminary insight into the potential of TMS as an intervention for depression in individuals with Autism Spectrum Disorder (ASD).
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
05/21/2024
Locations: Yale Psychiatric Hospital, New Haven, Connecticut
Conditions: Autism Spectrum Disorder
Register for Updates
Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant
NCT05203965
Recruiting
The purpose of this study is to evaluate the role of Mavoglurant in clarifying the neurobiology of alcoholism risk. This is a one-site, randomized, within subjects, counterbalanced double-blind study of a single dose (200mg) of Mavoglurant and placebo.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/21/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Familial Alcoholism Vulnerability
Register for Updates
OssDsign® Spine Registry Study ("Propel")
NCT05329129
Recruiting
The purpose of this multi-center, prospective, observational registry is to gather information on the clinical outcomes and real-world use of commercially available bone graft substitutes manufactured by OssDsign® AB, in patients who require spine fusion.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
05/20/2024
Locations: Orthopedic Associates of Hartford, Hartford, Connecticut
Conditions: Degenerative Disc Disease, Spinal Stenosis
Register for Updates
Peru Decentralized HIV Care
NCT05910268
Recruiting
The purpose of this study is to understand the processes by which HIV care is decentralized, an evidence-informed strategy to improve retention in HIV care, in Peru. Decentralization of HIV services has not been evaluated using experimental designs and urban decentralization studies of HIV are uncommon, so this study will lend important insights for future decentralization efforts in Peru and other countries.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Yale University, New Haven, Connecticut
Conditions: HIV
Register for Updates
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)
NCT04474223
Recruiting
Fetal complete (i.e., third degree, 3°) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally associated with maternal anti-Ro autoantibodies and results in death in a fifth of cases. To date treatment of 3° AVB has been ineffective in restoring normal rhythm (NR) which may be because current surveillance is limited to once- weekly fetal echocardiograms. It is hypothesized that there may be a vital transition p... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: AVB - Atrioventricular Block, Fetal AVB
Register for Updates