Connecticut is currently home to 1248 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study
NCT04721418
Recruiting
The purpose of this research study is to measure synaptic density in the brain comparing individuals with cocaine use disorder to healthy controls.
Gender:
ALL
Ages:
Between 21 years and 60 years
Trial Updated:
10/29/2024
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Cocaine Use Disorder, Healthy Controls
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CAPO: Continuous Glucose Monitoring in A2 Gestational Diabetes and Pregnancy Outcomes
NCT04219085
Recruiting
This study will utilize continuous glucose monitoring in women with A2 gestational diabetes. Women will be randomized to continuous glucose monitoring or routine care with fingersticks to check their blood glucose four times daily. It is hypothesized that women in the continuous glucose monitoring arm will have a lower incidence of the composite primary outcome, which includes the following variables: perinatal death, shoulder dystocia, birth weight greater than 4,000 grams, NICU admission for t... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
10/25/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Gestational Diabetes, Maternal Complication of Pregnancy
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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
NCT05486572
Recruiting
The study is a randomized trial of two different screening methods for early detection of liver cancer in patients with cirrhosis of the liver. The goal of PREMIUM is to compare an abbreviated version of the diagnostic gold standard for HCC (aMRI) +AFP to the standard-of-care screening (US+AFP) in patients at high risk of developing HCC. The investigators hypothesize that HCC will be detected at earlier stages, allowing for more curative treatments and resulting in a reduction in HCC-related mor... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/24/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Carcinoma, Hepatocellular, Cirrhosis
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A Study to Learn How Different Amounts and Forms of the Study Medicine Called PF-06414300 Act in Healthy Adults
NCT06659250
Recruiting
The purpose of this study is to learn about how different amounts of study medicine called PF-06414300 acts and is changed and eliminated from the body of healthy adult participants. The amount of PF-06414300 in blood after the medicine is taken by mouth will also be measured. The study is seeking for participants who: * Are male or female of 18 to 65 years of age. * Are in good health condition. * Have body mass index of 16 to 32 kilograms per squared meters; and a total body weight of more t... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/23/2024
Locations: Pfizer Clinical Research Unit - New Haven, New Haven, Connecticut
Conditions: Healthy Participants
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Trial of Therapeutic Hypothermia in Patients With ARDS
NCT04545424
Recruiting
Acute Respiratory Distress Syndrome (ARDS) is a serious condition that occurs as a complication of medical and surgical diseases, has a mortality of \~40%, and has no known treatment other than optimization of support. Data from basic research, animal models, and retrospective studies, case series, and small prospective studies suggest that therapeutic hypothermia (TH) similar to that used for cardiac arrest may be lung protective in patients with ARDS; however, shivering is a major complication... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/23/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Respiratory Distress Syndrome, Adult
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Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain
NCT06004804
Recruiting
This study is being performed to compare the effects of three types of group-based psychological treatments delivered over video telehealth for chronic musculoskeletal pain in older U.S. military Veterans. The three types of psychological treatments are: Cognitive-Behavioral Therapy (CBT), Emotional Awareness and Expression Therapy (EAET), and Mindfulness Meditation (MM). In addition, the investigators will evaluate which patients respond best to each treatment and how each treatment works. The... Read More
Gender:
ALL
Ages:
Between 60 years and 95 years
Trial Updated:
10/21/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Chronic Musculoskeletal Pain
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The EXPLORE MG Registry for Myasthenia Gravis
NCT03792659
Recruiting
The purpose of this study is to create a Yale University Department of Neurology Myasthenia Gravis (MG) registry that will be used for current and future research projects involving the study of Myasthenia Gravis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/21/2024
Locations: Yale-New Haven Hospital, New Haven, Connecticut
Conditions: Myasthenia Gravis
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Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity
NCT05700916
Recruiting
The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/16/2024
Locations: University of Connecticut, Storrs, Connecticut
Conditions: Dyslipidemias, Obesity
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Medical-legal Partnerships to Prevent Evictions and Homelessness Among Veterans
NCT04924088
Recruiting
The legal team in medical-legal partnerships works with healthcare providers to improve their clients' lives. It is unknown whether this approach is better than providing usual legal services, with no special emphasis on non-legal matters and no particular collaboration with healthcare providers. The investigators propose to randomly assign 300 Veterans with housing-related legal problems to either legal help from a medical-legal partnership or help from lawyers in the community. The investigato... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Homelessness, Mental Health
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Longitudinal Neural Fingerprinting of Opioid-use Trajectories
NCT06207162
Recruiting
This project aims to collect a densely sampled neuroimaging dataset among individuals receiving medications for opioid use disorder (MOUD). MOUD is multiphasic, comprised of medication induction, stabilization, ongoing treatment, and eventual dis-continuation phases. However, with a few small exceptions, existing neuroimaging efforts are almost exclusively single time-point assessments which, by definition, fail to capture these clinically relevant transitions and thus also do not capture indivi... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
10/11/2024
Locations: MRRC at The Anlyan Center, New Haven, Connecticut
Conditions: Opioid Use Disorder
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Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery
NCT06642051
Recruiting
The goal of this clinical trial is to learn if the Sonablate High Intensity Focused Ultrasound device can be safely used to treat patients with Chronic Venous Incompetence (CVI) including those with venous malformations of the periphery meaning legs, abdomen, chest or back. Examples of CVI are varicose veins, vascular congestion, venous ulcer, venous clusters, venous anomalies, mixed malformation, Klippel-Trenaunay Syndrome, CLOVES, Syndrome, Blue Rubber bleb Nevus Syndrome. HIFU is a non-invasi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: The Vascular Care Group, Darien, Connecticut
Conditions: Chronic Venous Insufficiency, CVI, Venous Malformations, Venous Leg Ulcers, Klippel-Trenaunay Syndrome, CLOVES Syndrome, Blue Rubber Bleb Nevus Syndrome
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Impact of Work Activity on SUD Outcomes
NCT04969081
Recruiting
To date, there are no studies of the therapeutic effects of varied work-focused programs in Veterans undergoing outpatient substance use disorder (SUD) treatment. The investigators propose a randomized clinical trial to test the effects of work-focused programs on improving sobriety and other clinical outcomes in Veterans early in the course of recovery from SUD. Veterans will be randomized to either receive or not receive referral for work-focused therapeutic programs. Primary aim is to examine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Substance-related Disorders
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