Connecticut is currently home to 1247 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Neuroblastoma Maintenance Therapy Trial
NCT02679144
Recruiting
Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to prevent recurrence.
Gender:
ALL
Ages:
Between 1 year and 30 years
Trial Updated:
09/18/2024
Locations: Connecticut Children's Hospital, Hartford, Connecticut
Conditions: Neuroblastoma
Register for Updates
Evaluating the Impact of Social Music
NCT06513910
Recruiting
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of PADs or other marginalized groups and are not designed to be culturally relevant or co... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates
Evaluating Social Perception Dynamics
NCT06513871
Recruiting
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of PADs or other marginalized groups and are not designed to be culturally relevant or co... Read More
Gender:
ALL
Ages:
Between 16 years and 65 years
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates
Evaluating the Community Drum Circle
NCT06513858
Recruiting
Mental health vulnerability due to stress is increased America due to disproportionate effects of social factors such as racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of Persons of African Descent(PAD) or other marginalized groups and are not designed to be culturally rel... Read More
Gender:
ALL
Ages:
Between 16 years and 65 years
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates
Drum Circle Synchrony Study 2c.a.
NCT06513845
Recruiting
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of PADs or other marginalized groups and are not designed to be culturally relevant or co... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates
Music Mindfulness Study 2a.
NCT06505226
Recruiting
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of PADs or other marginalized groups and are not designed to be culturally relevant or co... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates
A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults
NCT05518500
Recruiting
This is a prospective, single-arm study designed to understand the mechanisms that lead to a loss of response to influenza vaccine in older adults. The investigators will recruit and longitudinally follow a cohort of 75 older adults (65 years and older) who will receive three different influenza vaccines over three annual influenza seasons. Blood samples will be collected from the participants at sixteen study visits over three years. Nasal swab and stool samples will also be collected from part... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
09/17/2024
Locations: UConn Health, Center On Aging, Farmington, Connecticut
Conditions: Aging, Influenza Vaccine, Dendritic Cell, Vaccine Response
Register for Updates
Mechanisms Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 3
NCT04649229
Recruiting
This is a double-blind, randomized, two x two crossover (aprepitant vs placebo) during both initiation of Entresto, LCZ696, (50 mg dose) and at steady-state of Entresto (200 mg bid dose or the highest tolerated dose).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/06/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Heart Failure
Register for Updates
SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy
NCT05586581
Recruiting
The purpose of this study is to longitudinally characterize and evaluate changes in synaptic density in the brain using novel positron-emission tomography (PET) scans; magnetic resonance imaging (MRI), and clinical laboratory markers associated with HIV-related injury in the central nervous system. This study will test hypotheses relating to the presence and mechanisms of aberrant brain structure at the synaptic level in living humans with virologically controlled HIV on antiretroviral therapy.... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/05/2024
Locations: Yale School of Medicne, Neuro ID Research Program, New Haven, Connecticut
Conditions: HIV Associated Neurocognitive Disorder, HIV Dementia, HIV Encephalitis, Healthy
Register for Updates
Strengthening the Connections to Opportunities for Prevention Engagement
NCT06442046
Recruiting
The Strengthening the Connections to Opportunities for Prevention Engagement (SCOPE) project will create a pathway for children and families from the City of Hartford to connect with a Connecticut Children's Care Coordinator (CC) in an effort to reduce levels of violence exposure.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
09/04/2024
Locations: Connecticut Children's, Hartford, Connecticut
Conditions: Interpersonal Violence, Structural Violence
Register for Updates
Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers
NCT06196008
Recruiting
This clinical trial compares telephone-based physical activity coaching to self monitored physical activity for improving physical function in older adults who are undergoing surgery for lung cancer and their caregivers. Lung cancer surgery in older adults is associated with functional declines and unique challenges. Performing physical activity around the time of surgery has been shown to improve functional outcomes in patients and exercise programs delivered via telehealth may improve access a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/04/2024
Locations: Yale New Haven Medical Center, New Haven, Connecticut
Conditions: Lung Carcinoma
Register for Updates
Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study
NCT05612594
Recruiting
The goal of this clinical trial is to test if bexagliflozin lowers the sleep apnea severity in adults who are overweight or obese with moderate to severe obstructive sleep apnea (OSA) compared with a placebo (look-alike substance that contains no active drug). The main question it aims to answer is: * If SGLT2i will reduce anatomic and physiologic traits, clinical measures of OSA and sleep deficiency in participants * If improvement in clinical measures are because of improvement in the anatom... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/04/2024
Locations: Yale New Haven Health, New Haven, Connecticut
Conditions: Sleep Apnea
Register for Updates