Connecticut is currently home to 1248 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Open Versus Arthroscopic Stabilization of Shoulder Instability with Subcritical Bone Loss: the OASIS Trial
NCT04809064
Recruiting
This clinical trial will investigate the effects of three surgical procedures and the associated post-operative rehabilitation to optimize time to return to military duty, work and sports, and patient-reported physical function for military personnel and civilians with traumatic anterior shoulder instability and 10-20% glenoid bone loss.
Gender:
ALL
Ages:
Between 17 years and 50 years
Trial Updated:
10/08/2024
Locations: University of Connecticut Health Center, Farmington, Connecticut
Conditions: Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
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Aspiration in Acute Respiratory Failure Survivors 2
NCT05108896
Recruiting
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Dysphagia, Aspiration
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A Study of Sacituzumab Govitecan (IMMU-132) in Platinum-resistant Ovarian Cancer Patients
NCT06028932
Recruiting
This is a non-randomized Phase 2 study of sacituzumab govitecan (IMMU-132) in subjects with recurrent or persistent platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancers.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut
Conditions: Ovarian Carcinoma
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Mechanisms of Diuretic Resistance in Heart Failure, Aim 3
NCT06209359
Recruiting
Randomized double-blind placebo-controlled crossover study design
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure, Diuretic Resistance
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Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients
NCT05784805
Recruiting
In this study, the investigators propose Pulsed Low-Intensity Focused Ultrasound (PLIFU) stimulation of brain regions that modulate (thalamus) or generate focal motor seizures (primary motor cortex), with the goal of ameliorating seizure activity in subjects in non-convulsive or focal motor status epilepticus. The course of treatment will consist of an initial 10 minute PLIFU treatment session with an option for a 2nd session if necessary. The primary objective of this study is to determine whe... Read More
Gender:
ALL
Ages:
Between 19 years and 85 years
Trial Updated:
10/01/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Seizures
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IV Pulsed-Nicotine As a Model of Smoking: the Effects of Dose and Delivery Rate
NCT05176418
Recruiting
This project will examine the impact of the nicotine dose and delivery rate on nicotine's abuse potential, versus its potentially beneficial effects on smoking urges and withdrawal. Will use pulsed IV nicotine administration which closely matches nicotine delivery by inhaled tobacco use.
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
09/30/2024
Locations: VA Healthcare System, West Haven, Connecticut
Conditions: Nicotine Dependence
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Clinical Study of External Electrical Stimulation for Male Incontinence
NCT06620419
Recruiting
The purpose of this research is to evaluate the effectiveness of the Elidah neuromuscular stimulation treatment to reduce incontinence in men post-prostatectomy.
Gender:
MALE
Ages:
Between 18 years and 80 years
Trial Updated:
09/27/2024
Locations: Elidah, Monroe, Connecticut
Conditions: Urinary Incontinence
Register for Updates
Utility of PCD Diagnostics to Improve Clinical Care
NCT05889013
Recruiting
This cross-sectional and longitudinal observational study is to gather data on the utility of tests that are used to make a diagnosis of primary ciliary dyskinesia (PCD). There is new testing available, called nasal nitric oxide testing, that non-invasively measures nitric oxide levels in the sinus cavity. Individuals with PCD characteristically have low levels, but this testing does not have extensive data from everyday clinical practice. The objective of this proposal is to improve the diagnos... Read More
Gender:
ALL
Ages:
2 years and above
Trial Updated:
09/26/2024
Locations: Pulmonary Division, Hartford, Connecticut
Conditions: Primary Ciliary Dyskinesia
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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
NCT03827694
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
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Neuroblastoma Maintenance Therapy Trial
NCT02679144
Recruiting
Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter, study for patients with neuroblastoma in remission. In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to prevent recurrence.
Gender:
ALL
Ages:
Between 1 year and 30 years
Trial Updated:
09/18/2024
Locations: Connecticut Children's Hospital, Hartford, Connecticut
Conditions: Neuroblastoma
Register for Updates
Evaluating the Impact of Social Music
NCT06513910
Recruiting
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of PADs or other marginalized groups and are not designed to be culturally relevant or co... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates
Evaluating Social Perception Dynamics
NCT06513871
Recruiting
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured reductions in multiple negative dimensions of stress. However, the majority of these studies do not have an adequate representation of PADs or other marginalized groups and are not designed to be culturally relevant or co... Read More
Gender:
ALL
Ages:
Between 16 years and 65 years
Trial Updated:
09/17/2024
Locations: BLOOM, New Haven, Connecticut
Conditions: Mental Health Issue, COVID-19
Register for Updates