Kansas is currently home to 886 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Bioequivalence Study Between Adagrasib Reference Tablets and High Drug Load Tablets
NCT06801418
Recruiting
This is a study to evaluate bioequivalence between adagrasib reference tablets and high drug load tablets in healthy adult participants.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
02/25/2025
Locations: ICON - Lenexa, Lenexa, Kansas
Conditions: Healthy Volunteers
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A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
NCT06667661
Recruiting
The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the guidelines for physical activity, sedentary behavior, and sleep. The main questions it aims to answer are: * Can the intervention increase the proportion of children meeting all three 24-Hour Movement Guidelines (physical activity, screen-time, and sleep)? * Is the interventio... Read More
Gender:
ALL
Ages:
Between 3 years and 4 years
Trial Updated:
02/25/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Healthy, 24-Hour Movement Guidelines, Feasibility Studies, Sleep, Physical Activity, Screen Time, Sedentary Behaviors, Motor Skills, Cognition, Parent-Child Relations, Mobile Application, Health Education, Child Development
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To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications
NCT06553027
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter study in participants with Parkinson's disease (PD) with motor fluctuations. Participants will be randomized to receive once-daily oral doses of either 75 milligrams (mg) CVN424, 150 mg CVN424, or a matching placebo for 12 weeks. Participants who successfully complete this study and retain eligibility/suitability will be invited to participate in a future open-label extension (OLE) study.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
02/25/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Parkinson Disease
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Amplatzer Amulet LAAO Vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Kansas University Medical Center, Kansas City, Kansas
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
NCT03907046
Recruiting
Primary Aim: To determine if apixaban is superior to aspirin for prevention of the composite outcome of any stroke (hemorrhagic or ischemic) or death from any cause in patients with recent ICH and atrial fibrillation (AF). Secondary Aim: To determine if apixaban, compared with aspirin, results in better functional outcomes as measured by the modified Rankin Scale.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: University of Kansas Hospital, Kansas City, Kansas
Conditions: Intracerebral Hemorrhage, Atrial Fibrillation
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A Dose Finding Study of Debio 4228 in Participants With Locally Advanced/Metastatic Prostate Cancer
NCT06395753
Recruiting
The primary purpose of this study is to determine the pharmacokinetics (PK) and pharmacodynamics (PD) of Debio 4228.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: GU Research Network/Wichita Urology Group, Wichita, Kansas
Conditions: Prostate Cancer
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First Time in Human Study of Long Acting VH4524184 Formulations
NCT06310551
Recruiting
The purpose of this study is to identify 1 or more doses of parenterally administered VH4524184 that are safe, well tolerated and yield a PK drug exposure profile necessary to deliver a long-acting antiretroviral therapy for the treatment of HIV-1 infection.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/21/2025
Locations: GSK Investigational Site, Lenexa, Kansas
Conditions: HIV Infections
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Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
NCT05382299
Recruiting
The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) versus treatment of physician's choice (TPC) in participants with previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors do not express programmed cell death ligand 1 (PD-L1) or in participants previously treated with anti-programmed cell death (ligand or protein) 1 (Anti-PD-(L)1) Agents in the early setting whose tumor... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: The University of Kansas Cancer Center,2000 Olathe Blvd, Kansas City, Kansas
Conditions: Triple Negative Breast Cancer, PD-L1 Negative
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A Study to Investigate the Interaction Between TMP-301 and Cocaine.
NCT06648668
Recruiting
This will be a randomized, double-blind, placebo-controlled, parallel-group study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of oral TMP-301, given concurrently with cocaine. The study will consist of 4 phases: Screening, Baseline, Treatment, and Follow-up.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/20/2025
Locations: Dr. Vince Clinical Research, Overland Park, Kansas
Conditions: Cocaine Use Disorder
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Efficacy and Safety Study of OATD-01 in Patients with Active Pulmonary Sarcoidosis
NCT06205121
Recruiting
This is a Phase 2, randomized, double-blind, placebo-controlled, adaptive, multicenter study to evaluate the efficacy, safety, tolerability, Pharmacodynamics (PD), and Pharmacokinetics (PK) of OATD-01 in the treatment of subjects with active pulmonary sarcoidosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Molecure Investigative Site, Kansas City, Kansas
Conditions: Pulmonary Sarcoidosis
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ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
NCT05671510
Recruiting
The goal of this Phase 3 clinical trial is study the safety and efficacy of the nextgen anti-CTLA-4 antibody, gotistobart (ONC-392/BNT316), in patients with metastatic non-small cell lung cancer who have disease progressed on anti-PD-1/PD-L1 antibody based therapy. The study will test whether gotistobart, in comparison with chemotherapy agent docetaxel, could prolong the life for NSCLC patients. Patients will be randomized to be treated with either gotistobart or docetaxel, IV infusion, once eve... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Alliance for Multispecialty Research, LLC - 1144, Merriam, Kansas
Conditions: Non Small Cell Lung Cancer
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Deep Functional Phenotyping of the ALA Lung Health Cohort
NCT06177717
Recruiting
The goal of this observational study is to learn about lung structure and function in a group of 1000 healthy people aged 25 to 35. The main questions it aims to answer are whether people's bodies, environment, and general lung health are associated with: * the structure of the participants lungs' airways, * the structure of blood vessels in the participants lungs and heart, and * the participants lungs' ability to exchange gases. Participants will take four different lung function tests to me... Read More
Gender:
ALL
Ages:
Between 25 years and 35 years
Trial Updated:
02/19/2025
Locations: University of Kansas, Kansas City, Kansas
Conditions: Lung Diseases
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