Kansas is currently home to 923 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study of the Efficacy and Safety of NST-1024 Versus Placebo in Subjects With Hypertriglyceridemia
NCT05889156
Recruiting
This is a Phase IIa,multicentre proof of concept study consisting of 2 study periods to study Treatment with NST-1024 as an adjunct to diet to reduce triglyceride (TG) levels in subjects with TG levels of ≥500 mg/dL and ≤2000 mg/dL; determined by percentage change in TG from baseline after 28 days of treatment. The two periods consist of: 1. A 3-week screening period that includes a TG qualifying period, and 2. A 28-days, double-blind, randomized, parallel group, placebo-controlled treatment p... Read More
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
09/04/2024
Locations: Alliance for Multispecialty Research, LLC (AMR) - Newton, Newton, Kansas
Conditions: High Triglycerides
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A Multi-Component Weight Loss Intervention to Improve Outcomes of Total Knee Replacement
NCT05853497
Recruiting
Obesity, specifically BMIs ≥35 or 40 kg/m2, are associated with an increased probability of poor outcomes of Total Knee Arthroplasty (TKA) including increased pain, risk for infection, poor joint function, and increased rates of hospital readmissions. Several orthopedic and public health organizations recommend weight loss prior to TJA for individuals with overweight/obesity. However, empirical evidence suggesting the effectiveness of pre-surgical weight loss on surgical and functional outcomes... Read More
Gender:
ALL
Ages:
Between 50 years and 75 years
Trial Updated:
09/04/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Arthropathy of Knee, Obesity
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Testing Swim Instruction for Autistic Children
NCT06216613
Recruiting
The goal of this clinical trial is to compare the effects of a specialized swimming and water-safety program (Sensory Enhanced Aquatics) and standard swimming lessons for autistic children. The main question\[s\]it aims to answer are: * Do Sensory Enhanced Aquatics and standard swimming lessons improve swimming and water-safety skills of autistic children? * Which participant characteristics are associated with the highest post-intervention swim skills and water safety across both groups? Part... Read More
Gender:
ALL
Ages:
Between 5 years and 9 years
Trial Updated:
09/03/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Autism
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International Weight Control Registry
NCT04907396
Recruiting
The IWCR is a global scientific study aimed at better understanding the opportunities and barriers for reducing the prevalence of obesity by collecting information from people who have experience with weight management in their everyday lives. The investigators seek to gather information on a wide range of weight management experiences, ranging from weight loss and weight loss maintenance to weight gain and inability to lose weight.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/03/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Weight Loss, Overweight, Obesity
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Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve
NCT06583122
Recruiting
Study an ultrasound guided approach to radiofrequency ablation of the occipital nerve that makes it possible to see the needle during treatment procedure. It is hoped this will reduce the amount of pain after the standard of care procedure.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/30/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Nerve Pain
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Carbohydrate Ingestion Prior to Surgery (CIPS)
NCT06057532
Recruiting
The objective is to determine the impact of taking a specialized form of carbohydrate in the immediate preoperative period on metabolic markers, surgical outcomes and patient health. Patients will be randomized to receive a specialized sports drink or a standard sports drink. Patients will have a continuous glucose monitor (CGM) placed on their upper arm to measure glucose throughout surgery and during the post-operative period.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/30/2024
Locations: University of Kansas Health System, Kansas City, Kansas
Conditions: Urologic Surgical Procedures, Carbohydrate Loading, Preoperative Care
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Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis
NCT04767984
Recruiting
This phase II trial studies the effect of atorvastatin in treating patients with ulcerative colitis who have a dominant-negative missense P53 mutation and are at risk of developing large intestinal cancer. Patients with ulcerative colitis are known to have an increased risk of developing large intestinal cancer. Better ways to control ulcerative colitis and more knowledge about how to prevent colon cancer are needed. Atorvastatin is a drug used to lower the amount of cholesterol in the blood and... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/30/2024
Locations: University of Kansas Cancer Center, Kansas City, Kansas
Conditions: Ulcerative Colitis, Colorectal Carcinoma
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Head Positioning After Retina Detachment Repair
NCT03714503
Recruiting
This study aims to determine if one day post-operative prone head positioning can be as good as seven days post-operative prone head positioning in patients with retinal detachments with inferior retinal breaks after pars that pars plana vitrectomy (PPV) using perfluoropropane (C3F8) gas as a tamponade. The investigator will conduct a single arm phase II study using a Simon's two-stage design
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/30/2024
Locations: University of Kansas Medical Center, Prairie Village, Kansas
Conditions: Retina; Detachment, Rhegmatogenous
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ENCALM: a Study of ENX-102 As a Monotherapy Treatment in Patients with Generalized Anxiety Disorder
NCT05749055
Recruiting
The ENCALM trial is designed to evaluate the efficacy and safety of ENX-102 in patients diagnosed with generalized anxiety disorder (GAD)
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/29/2024
Locations: Collective Medical Research, Overland Park, Kansas
Conditions: Generalized Anxiety Disorder
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Dry Needling in Multiple Sclerosis
NCT06394310
Recruiting
The investigators are doing this study to see if a treatment called dry needling improves muscle spasticity (muscle tightness) in people who have Multiple Sclerosis. Dry needling involves using tiny needles, like those in acupuncture, to target some muscles, like calf muscles. It differs from traditional acupuncture as it focuses on treating or managing muscle spots, aiming to reduce muscle stiffness and pain. Dry needling may offer a minimally-invasive and medication-free approach to improve mu... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
08/28/2024
Locations: Mobility and Falls Lab, Kansas City, Kansas
Conditions: Multiple Sclerosis, Spasticity
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Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
NCT06001788
Recruiting
The safety, tolerability, and antileukemic response of ziftomenib in combination with standard of care treatments for patients with relapsed/refractory acute myeloid leukemia will be examined with the following agents: FLAG-IDA, low-dose cytarabine, and gilteritinib.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/28/2024
Locations: The University of Kansas, Kansas City, Kansas
Conditions: AML, AML With Mutated NPM1, Hematologic Malignancy, KMT2Ar, NPM1 Mutation, MLL Rearrangement, Leukemia, Acute Myeloid Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Acute Leukemia, Neoplasms by Histologic Type
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Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide
NCT04335682
Recruiting
This is a prospective, randomized, open-label phase II study comparing cognitive outcomes between men with metastatic and non-metastatic castration resistant prostate cancer (CRPC) or metastatic hormone sensitive prostate cancer (HSPC). Approximately 132 patients will be enrolled. Eligible patients will be randomized in a 1:1 fashion to treatment with enzalutamide 160 mg orally daily or darolutamide 600 mg orally twice daily, in combination with standard LHRH agonist based treatment. Cognitive a... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/28/2024
Locations: University of Kansas Cancer Center, Fairway, Kansas
Conditions: Metastatic Prostate Cancer, Prostate Cancer Metastatic, Prostate Cancer, Castrate Resistant Prostate Cancer, Hormone Sensitive Prostate Cancer, Non-metastatic Prostate Cancer
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