Kansas is currently home to 895 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Vaginal Photobiomodulation for Chronic Pelvic Pain
NCT06673108
Recruiting
The goal of this clinical study is to determine if 8 treatments with photobiomodulation using near-infrared laser energy can help reduce chronic pelvic pain in women. Additionally, researchers want to determine if treatment with this type of energy can also alleviate pain with activities such as standing, sitting, urinating, having bowel movements and intercourse.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: Urogynecology of Kansas City, Overland Park, Kansas
Conditions: Chronic Pelvic Pain, Chronic Pelvic Pain Syndrome (CPPS)
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Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases
NCT06671236
Recruiting
An open, multi- center phase Ⅰ clinical study evaluating the safety and efficacy of autologous human polyclonal regulatory T cell injection (NP001 cell injection) in patients with Neurodegenerative diseases (ALS, MSA, AD).
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/01/2024
Locations: Ascension Via Christi Clinic, Wichita, Kansas
Conditions: Amyotrophic Lateral Sclerosis (ALS), Alzheimer's Disease(AD), Multiple System Atrophy, MSA
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Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)
NCT03981575
Recruiting
Building on previous work of the Myotonic Dystrophy Clinical Research Network (DMCRN), the present study seeks to overcome insufficient data on natural history; lack of reliable biomarkers; and incomplete characterization and limited biological understanding of the phenotypic heterogeneity of Myotonic Dystrophy 1 by examining strategies to improve the reliability by making further refinements in our sample collection and analysis procedures by developing strategies for managing patient heterogen... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/31/2024
Locations: Kansas University Medical Center, Kansas City, Kansas
Conditions: Myotonic Dystrophy 1, DM1
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NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)
NCT05996003
Recruiting
This is a Phase 2, open-label, multi-center, 2-part study of NS-089/NCNP-02 administered by weekly IV infusion to ambulant boys aged ≥4 to \<15 years with DMD due to mutations amenable to exon 44 skipping. Participants will receive a selected dose of NS-089/NCNP-02 administered once weekly. The study consists of 2 parts: Part 1 and Part 2. Six participants (Cohort 1) will participate in both Part 1 and Part 2, and 14 participants (Cohort 2) will be added for Part 2.
Gender:
MALE
Ages:
Between 4 years and 14 years
Trial Updated:
10/30/2024
Locations: University of Kansas Medical Center (KUMC), Kansas City, Kansas
Conditions: Duchenne Muscular Dystrophy
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Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
NCT05850689
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) who have an inadequate response to ongoing ADT.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/30/2024
Locations: Clinical Site, Kansas City, Kansas
Conditions: Major Depressive Disorder
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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
NCT05929768
Recruiting
This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be bette... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: Cancer Center of Kansas - Chanute, Chanute, Kansas
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma
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Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials
NCT05108298
Recruiting
The purpose of this study is to evaluate feasibility and acceptability of completing PROs among AYAs randomized to Choice PRO vs Fixed PRO.
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
10/28/2024
Locations: Central Care Cancer Center - Garden City, Garden City, Kansas
Conditions: Breast Cancer, NOS, CNS Primary Tumor, NOS, Cervical Cancer, NOS, Colorectal Cancer, NOS, Leukemia, NOS, Lymphoma, NOS, Miscellaneous Neoplasm, NOS, Non-Rhabdomyosarcoma Soft Tissue Sarcoma, NOS, Testicular Nonseminomatous Germ Cell Tumor, NOS, Thyroid Cancer, NOS, Melanoma, Bone Cancer, NOS
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Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure
NCT06342492
Recruiting
This a single-center, retrospective, observational study of patients that undergo coronary sinus(CS) lead revision, comparing epicardial lead placement to coronary sinus pacing(CSP) in those that had lead failure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: Kansas City Heart Rhythm Institute, Overland Park, Kansas
Conditions: Heart Failure With Reduced Ejection Fraction
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Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study
NCT06289413
Recruiting
Observational two phase, retrospective and prospective registry study to assess the prevalence of and characterize outcomes of autonomic dysfunction (AD) in patients who undergo bariatric surgery (BS) and to better define the underlying pathophysiology of AD following BS.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/25/2024
Locations: Menorah Medical Center, Overland Park, Kansas
Conditions: Autonomic Dysfunction, Orthostatic Intolerance
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A Single and Multiple Ascending Dose Study of LAD603 in Healthy Subjects
NCT06200597
Recruiting
The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple ascending doses of LAD603 in healthy adult participants in both Part 1 and 2.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/25/2024
Locations: ICON Phase 1 unit Lenexa, Lenexa, Kansas
Conditions: Healthy Volunteers
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Vascular Closure With a Device Compared to Manual Compression After Atrial Fibrillation Ablation: The LockeT II Study
NCT06078735
Recruiting
The LockeT II study is a single center, prospective randomized study. It is intended to study the effectiveness of using LockeT device to gain hemostasis after venous procedures as compared to Manual Compression (MC). Approximately 110 patients will be enrolled.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas
Conditions: Atrial Fibrillation, Hemostasis
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Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry
NCT06075628
Recruiting
This study is intended to assess the incidence and correlation to the development of peri-device leaks (PDLs), device related thrombosis (DRTs) and cerebral vascular accident (CVA)/transient ischemic attacks (TIAs) in association with left atrial appendage contrast flow (LAA-CF). It will be a multi-center, retrospective study. Approximately 100 subject charts will be reviewed.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: Kansas City Heart Rhythm Institute, Overland Park, Kansas
Conditions: Atrial Fibrillation, Ischemic Stroke, Acute
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