Kansas is currently home to 924 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effect of a Quality Improvement Initiative to Address Social Determinants of Health on Rehospitalization Rates in Patients With Heart Failure
Recruiting
The objective of this program is to improve post-acute care coordination for necessary social services for patients leaving the hospital after recovering from an episode of decompensated heart failure.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/13/2024
Locations: Olathe Health System, Olathe, Kansas
Conditions: Heart Failure
REBYOTA™ Prospective Registry
Recruiting
This is a prospective observational cohort study designed to collect data on patients who received REBYOTA™ for the prevention of rCDI in the routine care setting. As all data collected for this study are observational, the decision to prescribe REBYOTA™ is at the treating physician's discretion and independent from the decision to enroll the patient in the study. Data will be collected from patients' medical records after obtaining informed consent. Data about clinical history, CDI events (prim... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: Ferring Investigational Site, Wichita, Kansas
Conditions: Recurrence of Clostridium Difficile Infection
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Recruiting
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
Gender:
All
Ages:
3 years and above
Trial Updated:
06/07/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis, Pulmonary Hypertension, Pulmonary Infection, Other Lung Disease
Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes
Recruiting
The purpose of this study is to assess the efficacy of metformin to improve airway ion channel function in those with CF-related diabetes (CFRD)
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Cystic Fibrosis-related Diabetes, Cystic Fibrosis
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
Recruiting
A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at high risk for COPD exacerbations.
Gender:
All
Ages:
40 years and above
Trial Updated:
06/06/2024
Locations: University of Kansas, Kansas City, Kansas
Conditions: Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
Early PKD Observational Cohort Study
Recruiting
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being develop... Read More
Gender:
All
Ages:
Between 4 years and 35 years
Trial Updated:
06/05/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Polycystic Kidney Disease
Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.
Recruiting
The goal of this clinical trial is to test use of losartan in those with cystic fibrosis (CF) on modulator therapy. The main question it aims to answer is if treatment with losartan improves response of the CF transmembrane conductance regulator (CFTR) channel to modulator therapy. Participants will be asked take losartan or placebo for twelve weeks and will have changes in sweat chloride levels measured as a marker of CFTR function.
Gender:
All
Ages:
12 years and above
Trial Updated:
06/04/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Cystic Fibrosis
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
This is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Artery Sensor System in NYHA Class II-III Heart Failure Patients (PROACTIVE-HF-2 Trial). The study contains of 5 arms: Randomized Arm - To demonstrate safety and efficacy of the Cordella PA Sensor System in NYHA Class II HF patients. Treatment Arm (Cohort 1) Active Control Arm (Cohort 2) Crossover Arm (Cohort 3) Single Arm - To demonstrate safety an... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: University of Kansas Medical Center (KUMC), Kansas City, Kansas
Conditions: Heart Failure NYHA Class II, Heart Failure NYHA Class III
Mitral Valve Screening Survey
Recruiting
This study aims to examine the clinical profile/anatomical characteristics and natural history of patients who subsequently fail screening for transcatheter mitral valve intervention (TMVI).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Mitral Valve Disease
One-Time DNA Study for Vasculitis
Recruiting
The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.
Gender:
All
Ages:
7 years and above
Trial Updated:
06/03/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis, Granulomatosis With Polyangiitis (Wegener's), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu's Arteritis
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Recruiting
The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with Down syndrome.
Gender:
All
Ages:
Between 35 years and 85 years
Trial Updated:
05/30/2024
Locations: University of Kansas Medical Center Research Institute, Fairway, Kansas
Conditions: Alzheimer's Disease, Prodromal Alzheimer's Disease, Amyloid Plaque, Beta-Amyloid, Alzheimer's Disease in Down Syndrome
Registry Study for Radiation Therapy Outcomes
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
All
Ages:
All
Trial Updated:
05/30/2024
Locations: University of Kansas Proton Therapy Center, Kansas City, Kansas
Conditions: Neoplasms