Kansas is currently home to 876 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Left Atrial Appendage Closure With WATCHMAN FLX Device in Recurrent Gastrointestinal Bleeding: The GI-FLX Registry
NCT06052358
Recruiting
The GI-FLX Registry is intended to create a registry of patients with a history of Atrial Fibrillation (AF) and Gastrointestinal (GI) bleed who will receive Left Atrial Appendage Closure (LAAC) with WATCHMAN FLX device and compare to patients with AF and GI bleed who do not have LAAC. The GI-FLX Registry will be a multi-center, non-randomized registry. Approximately 250 prospective patients will be enrolled at all 4 sites. Historical cohort of 250 patients after propensity score matching with WA... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2024
Locations: Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas
Conditions: Atrial Fibrillation, GI Bleeding
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Observational Study to Examine the Procedural and Outcomes of AF Ablation Assisted by STAR Apollo™ Mapping System
NCT05826665
Recruiting
STAR Apollo Mapping System is an FDA cleared mapping technology that can analyze the signals collected during the ablation procedure on the 3D mapping system and give the physician further insight into the AF activation patterns which may assist them in identifying areas responsible for maintaining Atrial Fibrillation (AF). The STAR Apollo Mapping System system allows clinicians, after treating the Pulmonary Veins (PV), to collect data from the atria during clinical AF procedures using standard... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/14/2024
Locations: Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas
Conditions: Persistent Atrial Fibrillation
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LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors
NCT04979156
Recruiting
Conventional monopolar or bipolar transurethral resection of bladder tumors is the most common method for resection of a bladder mass. En bloc resection has demonstrated success in the literature utilizing different techniques and lasers, including utilizing the Ho:YAG and Tm:YAG lasers. A recent metanalysis revealed several benefits to laser en bloc resection including less complications and lower recurrence rate.22 Subsequently, laser technology has also advanced with the development of a supe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Bladder Cancer, Surgery
Register for Updates
Exosomes in Rectal Cancer
NCT03874559
Recruiting
The primary aims of this study is to characterize exosomal biomarker levels in patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation therapy. Compare rates of exosomal expression before during and after chemoradiation therapy with pathologic response rates at the time of APR or LAR. The researchers will also examine the functionality of these exosomes in malignant colonic organoids and mouse models of colorectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: University of Kansas Medical Center/ Cancer Center, Kansas City, Kansas
Conditions: Rectal Cancer
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Moses Vaporization: Is Use of Moses 2.0 in Holmium Laser Ablation of the Prostate More Efficient
NCT04979143
Recruiting
To determine if use of Moses 2.0 results in improved ablation efficiency during holmium laser vaporization of the prostate. To determine if use of Moses 2.0 results in less char, improved visibility, and improved hemostasis in prostate vaporization.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Register for Updates
HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer
NCT03802851
Recruiting
To determine if holmium laser enucleation of the prostate (HoLEP) for the treatment of lower urinary tract symptoms (LUTS) and/or urinary retention alters the treatment course for patients concurrently diagnosed with prostate cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Kansas Health System, Kansas City, Kansas
Conditions: Prostate Cancer, Lower Urinary Tract Symptoms
Register for Updates
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
NCT06100276
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: University of Kansas Medical Center, Fairway, Kansas
Conditions: Amyotrophic Lateral Sclerosis
Register for Updates
Interstitial Lung Disease Research Unit Biobank
NCT05392881
Recruiting
Establish a interstitial lung disease (ILD) registry and biorepository to lead towards a further understanding of the disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Interstitial Lung Disease, Sarcoidosis, Idiopathic Pulmonary Fibrosis, Pulmonary Fibrosis, Hypersensitivity Pneumonitis
Register for Updates
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
NCT03295981
Recruiting
The purpose of the clinical study is to investigate whether the local delivery of bisphosphonate as a surgical adjuvant can decrease the chance of a giant cell tumor of bone coming back to the same location. The hypothesis is that the local administration of bisphosphonate will decrease the rate of the tumor returning compared to traditional aggressive surgical removal of the tumor.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Kansas, Overland Park, Kansas
Conditions: Giant Cell Tumor of Bone
Register for Updates
Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
NCT06379724
Recruiting
Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI® , and at a lower cost to the health system.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: The University of Kansas Health System, Kansas City, Kansas
Conditions: Burns, Skin Graft Complications
Register for Updates
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
NCT06129864
Recruiting
The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HNSCC) who have not progressed after receiving definitive concurrent chemoradiotherapy (cCRT).
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
10/02/2024
Locations: Research Site, Kansas City, Kansas
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Register for Updates
Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension
NCT06626113
Recruiting
In addition to chronically elevated MSNA, there is a growing recognition that hypertension in states of insulin resistance and obesity may also be attributed to an increased vascular sensitivity to MSNA (1, 2, 13, 36-38). To study this phenomenon, we quantify vascular sensitivity to MSNA using an innovative, moment-to-moment assessment of the blood pressure response following individual bursts of muscle sympathetic nerve activity (MSNA), (10, 11, 34, 37). This approach is termed 'sympathetic-vas... Read More
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
10/01/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Obesity
Register for Updates