Kansas is currently home to 954 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis
NCT03073694
Recruiting
The purpose of this trial is to compare the morbidity and mortality of CRS-HIPEC using mitomycin-C versus melphalan for colorectal peritoneal carcinomatosis. Morbidity and mortality will measured using the Comprehensive Complication Index (CCI) score, Common terminology criteria for adverse events (CTCAE version 4.03), and the Clavien-Dindo Classification.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/07/2023
Locations: The University of Kansas Medical Center, Westwood, Kansas
Conditions: Cancer, Appendiceal, ColoRectal Cancer
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Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
All
Ages:
All
Trial Updated:
05/26/2023
Locations: Kansas University Medical Center, Kansas City, Kansas
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
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One-Time DNA Study for Vasculitis
NCT01241305
Recruiting
The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/25/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis, Granulomatosis With Polyangiitis (Wegener's), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu's Arteritis
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Whole Egg Intake and Choline Concentration in the Aging Brain
NCT05021211
Recruiting
By doing this study, researchers hope to learn to see if there is relationship between whole egg consumption and brain choline status. Additionally, researchers also plan to see if there is a relationship between brain choline status and cognition.
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
05/24/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Alzheimer Disease
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Brain Responses to Contextual Influences on Drinking Decisions
NCT04895033
Recruiting
This study is using functional magnetic resonance imaging (fMRI) to examine brain activity associated with making decisions about drinking alcohol in everyday situations, some of which may involve important activities happening the next day. The secondary aims are to determine whether severity of alcohol-related problems is related to brain activity and alcohol choices and to examine how different areas of the brain interact in connected networks.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
05/24/2023
Locations: Cofrin Logan Center for Addiction Research and Treatment, Lawrence, Kansas
Conditions: Alcohol Drinking
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Impact of E-cigarette Nicotine Concentration on Compensation
NCT05887947
Recruiting
The study will be the first to assess the impact of nicotine concentration on compensatory puffing (total inhaled volume), nicotine delivery, and switch patterns (percent exclusive EC, dual cig-EC, and cig only users) with an explicit focus on AA and White smokers.
Gender:
All
Ages:
21 years and above
Trial Updated:
05/23/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Smoking Cessation
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Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES
NCT05688943
Recruiting
This study compares general anesthesia and spinal anesthesia for vNOTE tubal sterilization. A direct comparison of these methods has not been done before for this surgical approach. Investigators will aim to compare the two methods to determine the differences in perioperative complications, postoperative pain, postoperative nausea and vomiting, and the time to get the patient ready for discharge from the recovery room.
Gender:
Female
Ages:
21 years and above
Trial Updated:
05/20/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Anesthesia, Tubal Ligation
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PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
NCT04129931
Recruiting
The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/16/2023
Locations: University of Kansas, Kansas City, Kansas
Conditions: Asthma
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Post Operative Delirium Study
NCT04635774
Recruiting
Post-operative delirium happens when patients wake up from anesthesia. Patients experiencing post-operative delirium are very confused, not being able to think or function "normally". These patients are hard to take care of and they tend to have more dementia as they age compared to patients who don't experience post-operative delirium. Intranasal insulin has been shown to reverse confusion associated with Alzheimer's disease (humans) and AIDS (mice). Intranasal insulin has been safely administ... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
05/15/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Delirium
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Diagnostic Value of Weight Bearing CT for Detecting Meniscal Tears
NCT04430829
Recruiting
This observational study will compare the clinical value of weight-bearing CT arthrography (WBCTa) with that for MRI in evaluating meniscal and cartilage lesions of the knee joint. The MRI Osteoarthritis Knee Score (MOAKS) and modified MOAKS for WBCTa will be used to compare findings between MRI and WBCTa of the knee while comparing with surgical measurements using the ICRS scoring system. The study hypothesis is that meniscal and cartilage lesions may be missed by non-weight-bearing MRI, but d... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/15/2023
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Meniscus Tear, Tibial
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Sleep Hygiene Education, ReadiWatchTM Actigraphy, and Telehealth Cognitive Behavioral Training for Insomnia Effect, on Symptom Relief for Men With Prostate Cancer Receiving Androgen Deprivation Therapy
NCT05582759
Recruiting
Many treatments for prostate cancer can cause significant fatigue and/or problems with memory and concentration. Many treatments for prostate cancer also result in disturbed sleep. Improving sleep may reduce feelings of fatigue and improve memory and concentration. The purpose of this study is to test a wearable device that provides real-time feedback on sleep patterns, instruction on how to improve sleep, and a score that indicates periods of time when fatigue and issues with memory and concent... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: University of Kansas Cancer Center, Kansas City, Kansas
Conditions: Prostate Cancer, Sleep Disturbance, Fatigue, Cognitive Impairment
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Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer
NCT05143229
Recruiting
This study evaluates the safety and efficacy of sacituzumab govitecan plus alpelisib for treatment of metastatic or locally recurrent HER2-negative breast cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2023
Locations: The University of Kansas Clinical Research Center, Fairway, Kansas
Conditions: Breast Cancer
Register for Updates