Minnesota is currently home to 2105 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Mediterranean Diet Post-liver Transplantation
NCT04672863
Recruiting
The purpose of this study is to study the effects of a structured Mediterranean dietary program on prevention of weight gain, promotion of heart health and prevention of fatty liver disease after liver transplantation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/03/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Liver Transplantation
Register for Updates
Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
NCT03818178
Recruiting
Muscle insulin resistance is a hallmark of upper body obesity (UBO) and Type 2 diabetes (T2DM). It is unknown whether muscle free fatty acid (FFA) availability or intramyocellular fatty acid trafficking is responsible for muscle insulin resistance, although it has been shown that raising FFA with Intralipid can cause muscle insulin resistance within 4 hours. The investigators do not understand to what extent the incorporation of FFA into ceramides or diacylglycerols (DG) affect insulin signaling... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/03/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Insulin Resistance
Register for Updates
Corticosteroid Injection Versus Nerve Block
NCT06735027
Recruiting
The purpose of this study is to evaluate conservative pain relief measures for patients suffering from glenohumeral arthritis or rotator cuff arthropathy. Conservative management of osteoarthritis is often first line treatment, and while a corticosteroid injection is frequently used, suprascapular nerve blocks have not often been described as an analgesic option in this population.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
01/02/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Glenohumeral Arthritis, Rotator Cuff Arthropathy
Register for Updates
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
NCT06030063
Recruiting
The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who receive general anesthesia for cesarean delivery.
Gender:
FEMALE
Ages:
Between 15 years and 55 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cesarean Delivery, General Anesthesia
Register for Updates
Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
NCT05538247
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Real-Time Feedback (RTFB) to Improve Colonoscopy
NCT05241210
Recruiting
To test whether real-time feedback will improve quality of endoscopic examination.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/02/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Colorectal Cancer
Register for Updates
A Study of BI-1206 in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors (KEYNOTE-A04)
NCT04219254
Recruiting
Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1 Antibodies
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/02/2025
Locations: HealthPartners Institute - Regions Cancer Care Center,, Saint Paul, Minnesota
Conditions: Solid Tumor, Adult
Register for Updates
Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease
NCT02437396
Recruiting
The objective of this study is to evaluate oxidative stress and/or inflammation in patients with Gaucher disease type I using a series of biomarkers and correlate with measurements of currently used diagnostic biomarkers.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/02/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Gaucher Disease Type I, Oxidative Stress, Inflammation
Register for Updates
Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study
NCT05077735
Recruiting
This phase II trial studies the clinical outcomes of hypofractionated radiation therapy in patients with diffuse midline gliomas. This study aims to change the way radiation is delivered, from giving 6 weeks of radiation all at once to giving 2 weeks of radiation. This may determine if there is a difference in the outcome of the treatment, and most importantly, the patients' quality of life.
Gender:
ALL
Ages:
1 year and above
Trial Updated:
12/31/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant
Register for Updates
AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction
NCT06580158
Recruiting
Two recently developed artificial intelligence-enabled electrocardiogram (AI-ECG) models have been developed to detect aortic stenosis (AS) and diastolic dysfunction (DD). AI-ECG for AS has a sensitivity of 78% and specificity of 74%, and AI-ECG for DD has a sensitivity of 83% and specificity of 80%. However, these models have never been prospectively applied to diagnose AS or DD, which may be useful for patients and providers from a diagnostic and prognostic perspective and especially in settin... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
12/30/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Aortic Stenosis, Diastolic Dysfunction
Register for Updates
Full-mouth Electronic Toothbrush Vs. Conventional Electronic Toothbrush
NCT06561204
Recruiting
The goal of this randomized, masked-examiner clinical trial is to investigate a full-mouth electronic toothbrush (FMET). The three arms are: 1) FMET + American Dental Association (ADA) approved dentifrice, 2) conventional electronic toothbrush (ETB) + ADA dentifrice and 3) FMET + foam system.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/30/2024
Locations: University of Minnesota School of Dentistry, Minneapolis, Minnesota
Conditions: Toothbrush, Gingivitis, Plaque
Register for Updates
A Study of Sex Differences in Neurocirculatory Control
NCT06261034
Recruiting
The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).
Gender:
ALL
Ages:
Between 20 years and 70 years
Trial Updated:
12/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Obstructive Sleep Apnea
Register for Updates