Minnesota is currently home to 2099 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Phase 3 Study of the Safety and Efficacy of Coagulation Factor VIIa (Recombinant) for the Prevention of Excessive Bleeding in Patients With Congenital Hemophilia A or B With Inhibitors to Factor VIII or IX Undergoing Elective Major Surgical Procedures SCOPE HIM
NCT05695391
Recruiting
This is an interventional, prospective, international, multicenter, single-arm, Phase 3, and sequential efficacy and safety study in adolescents and adults with congenital hemophilia A or B with inhibitors to factor VIII (FVIII) or factor IX (FIX) undergoing elective major surgical procedures.
Gender:
MALE
Ages:
Between 12 years and 65 years
Trial Updated:
09/26/2024
Locations: M Health Fairview Center for bleeding and Clotting disorders, Minneapolis, Minnesota
Conditions: Hemophilia
Register for Updates
Olorofim Aspergillus Infection Study
NCT05101187
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Invasive Aspergillosis
Register for Updates
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
NCT04984473
Recruiting
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy, Heart Failure
Register for Updates
Assessment of Usability and Satisfaction With a Take-home Device Presenting Sound and Body Stimulation for Back Pain
NCT06619418
Recruiting
Pain symptoms can have a variety of ways to be treated, from medications to physical therapy, with several options being available to patients. However, no one treatment may work for all people who experience pain, especially cLBP. The purpose of this study is to measure the compliance, usability, and satisfaction of an at-home, multi-modal stimulation device in a diverse population of people with chronic lower back pain (cLBP). The multi-modal device will include a combination of electrical sti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Chronic Lower Back Pain
Register for Updates
Clinical Trial of Concomitant Hip Arthroscopy During PAO
NCT03181048
Recruiting
The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated with PAO alone.
Gender:
ALL
Ages:
Between 15 years and 55 years
Trial Updated:
09/25/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Hip Dysplasia
Register for Updates
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
NCT06617494
Recruiting
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases. Despite advances in understanding TMD pathophysiology, the role of central sensitization, particularly deficient endogenous pain inhibition, remains unclear. The conditioned pain modulation (CPM) test, used to assess pain inhibition in chronic TMD pain, has produced inconsistent resul... Read More
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
09/24/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Chronic Temporomandibular Disorders (TMD)
Register for Updates
Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy
NCT06238648
Recruiting
This phase II trial compares epcoritamab to standard practice (observation) for the treatment of patients with B-cell lymphomas who are not in complete remission after treatment with CD19-directed chimeric antigen receptor T-cell (CAR-T) therapy. Epcoritamab is a bispecific antibody. It works by simultaneously attaching to a molecule called CD20 on cancerous B-cells and a molecule called CD3 on effector T-cells, which are a type of immune cell. When epcoritamab binds to CD20 and CD3, it brings t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Primary Mediastinal Large B-Cell Lymphoma, Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Register for Updates
STOP-HER2: Stopping Trastuzumab in HER2+ MBC
NCT05721248
Recruiting
This study is being done to see if anti-HER2 treatment be safely stopped in patients with HER2-positive metastatic breast cancer (MBC) that have had exceptional response to treatment. Exceptional response" is considered as cancer progression being controlled for three years or more since starting anti-HER2 treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Breast Cancer, Metastatic Breast Cancer, HER2-positive Breast Cancer
Register for Updates
Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
NCT04228978
Recruiting
The PROVE Trial is a randomized clinical trial that will determine whether a weight loss intervention combined with walking exercise achieves greater improvement or less decline in six-minute walk distance at 12 month follow-up than walking exercise alone in people with PAD and BMI\>25 kg/m2. The intervention uses a Group Mediated Cognitive Behavioral framework, connective mobile technology, remote monitoring by a coach, and a calorie restricted Dietary Approaches to Stop Hypertension (DASH)-der... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease, Overweight or Obesity
Register for Updates
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
NCT03827694
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: University of Minnesota Medical School, Minneapolis, Minnesota
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
Register for Updates
A Prospective Research Investigation of Ischemia Using MCG
NCT06481943
Recruiting
PRISM is a prospective, pilot research study that aims to systematically characterize the usefulness of CardiAQ MCG, a bedside magnetocardiography device, in the evaluation of myocardial ischemia and infarction status.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Acute Coronary Syndrome
Register for Updates
A Clinical Registry of Spontaneous Intracranial Hypotension
NCT05922514
Recruiting
The purpose of this research is to determine the efficacy of paraspinal vein embolization for treatment of digital subtraction myelography (DSM) or CT myelography (CTM) confirmed cerebrospinal fluid (CSF)-venous fistulas so that researchers can inform the development and design of future clinical trials of this technique.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Spontaneous Intracranial Hypotension
Register for Updates