Minnesota is currently home to 2064 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Rare Kidney Stone Consortium Biobank
NCT02026388
Recruiting
This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.
Gender:
ALL
Ages:
All
Trial Updated:
07/15/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Primary Hyperoxaluria, Dent Disease, APRT Deficiency, Cystinuria
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A Phase 2 Study of VLX-1005 Versus Placebo in Suspected Heparin Induced Thrombocytopenia
NCT05785819
Recruiting
The purpose of this study is to evaluate the efficacy and safety of VLX-1005, a 12-lipoxygenase (12-LOX) enzyme inhibitor in treating heparin induced thrombocytopenia (HIT). Participants with suspected HIT will receive the usual standard of care, and will be assigned randomly to either VLX-1005 or placebo treatment. The study will measure important outcomes including platelet count, stroke, pulmonary embolus (clot to the lungs) and bleeding.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Thrombocytopenia, Immune, Heparin Induced Thrombocytopenia
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A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities
NCT05671380
Recruiting
This project will evaluate a proactive outreach intervention for tobacco cessation among primary care BIPOC populations who smoke in two health systems across the region. Compared with Whites, BIPOC populations in the US experience disproportionate health consequences from commercial cigarette use. Few evidence-based cessation treatments (EBCTs) have been specifically developed, evaluated, or implemented for BIPOC populations. Moreover, uptake of EBCT (e.g. medication, counseling) is lower among... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: Hennepin Healthcare, Minneapolis, Minnesota
Conditions: Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
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Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
NCT04373317
Recruiting
Patients with Parkinson's disease (PD) sometimes experience symptoms affecting their movement, such as slowness, tremor, stiffness, and balance or walking problems. Many patients also have other symptoms not related to movement, called non-motor symptoms, which may affect one's mood or emotions, memory or thinking, or cause one to see or hear things that aren't real (hallucinations) or believe things that aren't true (delusions). Hallucinations or delusions, together called psychosis, occur in u... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
07/12/2024
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: Parkinson's Disease Psychosis
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Syncing Screening and Services for Suicide Prevention Across Health and Justice Systems
NCT06506344
Recruiting
This study aims to harmonize jail release record data with electronic health record data in order to connect patients to an evidence-based suicide prevention and clinical care pathway upon jail release.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: HealthPartners Institute, Bloomington, Minnesota
Conditions: Suicide Prevention
Register for Updates
Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
NCT06194305
Recruiting
Tourette Syndrome and Persistent Motor/Vocal Tic Disorder affect 1-3% of youth and can be associated with impaired functioning, emotional and behavioral problems, physical pain, diminished quality of life, and peer victimization. Chronic tics are the primary symptom. Comprehensive Behavioral Intervention for Tics (CBIT) is a manualized treatment focused on tic management skills. During the core CBIT procedure, competing response training, patients learn to inhibit tics by engaging in a competing... Read More
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
07/11/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Tourette Syndrome, Persistent Tic Disorder
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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
NCT05646316
Recruiting
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera to look for cancer that may have spread to nearby... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Fairview Southdale Hospital, Edina, Minnesota
Conditions: Stage I Uterine Corpus Cancer AJCC v8
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PARADIGM: Amplatzer Valvular Plug for PVL Closure
NCT04489823
Recruiting
The Paradigm study is a prospective, multicenter, single arm study to demonstrate the safety and effectiveness of the Amplatzer Valvular Plug III (AVP III) as a treatment for clinically significant PVLs following surgical implant of a mechanical or biological heart valve implanted in the aortic or mitral position.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: Minneapolis Heart Institute, Minneapolis, Minnesota
Conditions: Paravalvular Aortic Regurgitation
Register for Updates
A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle
NCT05856136
Recruiting
The purpose of this study is to evaluate opioid dose effects on the ability of the diaphragm muscle to generate higher force behaviors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Respiratory Function Loss, Respiratory Complication
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Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
NCT05459233
Recruiting
Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between echocardiography and catheterization, with an overestimation of the real gradient with echo (vs. cath) in most cases. Thus, the incidence of procedural-device failure may be lower than that reported in the ViV-TAVR literature,
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Aortic Valve Stenosis, Aortic Valve Regurgitation, Prosthesis Failure
Register for Updates
Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury
NCT05236010
Recruiting
The CONNECT-TBI Trial aims to develop safe, effective treatments for complex mTBI that improve cognitive functioning. Based on the compelling preliminary data generated by our study team, the objective of this study is to conduct a randomized, double-blinded, sham-controlled Phase II clinical trial of APT-3 combined with rTMS, HD-tDCS, or sham to treat cognitive control deficits in Veterans with complex mTBI and PPCS. At the Baseline Visit, participants will undergo demographic, neuropsychologic... Read More
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
07/10/2024
Locations: Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota
Conditions: Traumatic Brain Injury
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ARrest RESpiraTory Failure From PNEUMONIA
NCT04193878
Recruiting
This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: Mayo Clinic - Rochester, Rochester, Minnesota
Conditions: Pneumonia, Hypoxemia, Acute Respiratory Failure, COVID-19 Pneumonia
Register for Updates