Minnesota is currently home to 2064 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Treatment of Upper Gastrointestinal Symptoms Using Hypnotherapy Sessions
NCT06846359
Recruiting
The purpose of this research is to evaluate if hypnotherapy delivered digitally will help your GI symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: GI Symptoms
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Home-based Pulmonary Rehabilitation and Health Coaching in Patients With Fibrotic Interstitial Lung Disease
NCT06751069
Recruiting
The purpose of this clinical trial is to determine the impact of a home-based pulmonary rehabilitation program with health coaching on patient-reported respiratory-related quality of life and physical activity, as compared to usual care in patients with fibrotic interstitial lung disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Lung Fibrosis, Lung Interstitial Disease
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A Study to Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia Asparaginase
NCT06600659
Recruiting
This study evaluates the incidence of symptomatic hyperammonemia (high ammonia levels) in patients being treated with recombinant Erwinia asparaginase.
Gender:
ALL
Ages:
1 year and above
Trial Updated:
03/10/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hematopoietic and Lymphatic System Neoplasm, Acute Lymphobkastic Leukemia
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Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma
NCT06517888
Recruiting
This trial will evaluate the safety and tolerability of a single unilateral administration of one of three dose levels of AAVAnc80-antiVEGF and will evaluate the Akouos delivery device to safely achieve the intended product performance.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Vestibular Schwannoma
Register for Updates
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
NCT06486441
Recruiting
The goal of this clinical study is to find out how the study drug, sacituzumab govitecan (SG) works in participants with endometrial cancer who have received prior treatment with platinum-based chemotherapy and immunotherapy, versus the treatment of physician's choice (TPC). The primary objectives of this study are to evaluate the effect of SG compared to TPC on progression-free survival (PFS) as assessed by blinded independent central review (BICR) and overall survival (OS).
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: M Health Fairview University of Minnesota Medical Center - East Bank Hospital, Minneapolis, Minnesota
Conditions: Endometrial Cancer
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SuperSaturated Oxygen Comprehensive Observational Registry
NCT06438315
Recruiting
The SuperSaturated Oxygen Comprehensive Observational Registry (SSCORE) registry, a prospectively designed observational study, aims to evaluate the clinical utility and effectiveness of SuperSaturated Oxygen (SSO2) Therapy versus percutaneous coronary intervention (PCI) alone among patients with anterior acute myocardial infarction (AMI) in routine clinical practice. The goal is to collect real-world data from patients treated with SSO2 Therapy to determine its impact on the overall heart failu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Mercy Hospital, Coon Rapids, Minnesota
Conditions: STEMI - ST Elevation Myocardial Infarction, AMI
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Open Label, Controlled, Post Marketing, Registry Study of Ribociclib (Ribo) Treatment Adherence and Patient Reported Outcomes in Participants Using ReX Technology Platform
NCT06344416
Recruiting
Primary Objective: • To assess the persistence of ReX technology platform use, measured by the percentage (%) of participants who used ReX: 1) throughout the study period and 2) before the treatment discontinuation. Secondary Objective: • To evaluate the impact of the ReX technology platform on ribo treatment duration and ribo dose taking adherence as compared to control group.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Allina, Minneapolis, Minnesota
Conditions: Any Solid Oral Medication
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Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis
NCT06141486
Recruiting
The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to 36 months double-blind administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at the time of enrollment). People diagnosed with nrSPMS are eligible for enrollment as long as they meet all the inclusion criteria and none of the exclusion criter... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
03/10/2025
Locations: Minneapolis Clinic of Neurology - Golden Valley- Site Number : 8400077, Golden Valley, Minnesota
Conditions: Multiple Sclerosis
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Bladder Bank (a Prospective Banking Study)
NCT06109857
Recruiting
This study collects blood and urine samples from patients with bladder cancer to support the development of tests for early detection of bladder cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Bladder Carcinoma
Register for Updates
A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Infants (0 to <2 Years of Age) With Achondroplasia
NCT06079398
Recruiting
This trial is a Phase 2, multicenter, double-blind, randomized (ratio 2:1 TransCon CNP vs. placebo), placebo-controlled trial, designed to evaluate the safety, tolerability, and efficacy of 100 μg CNP/kg of Navepegritide (TransCon CNP) administered SC once-weekly for 52 weeks in infants with genetically verified heterozygous ACH, aged 0 to \< 2 years at the time of randomization.
Gender:
ALL
Ages:
Between 0 years and 2 years
Trial Updated:
03/10/2025
Locations: Ascendis Investigational Site, Saint Paul, Minnesota
Conditions: Achondroplasia
Register for Updates
Helix Research Network
NCT06057181
Recruiting
The Helix Research Network ("HRN") is a network of academic, public, and/or private healthcare organizations that are committed to advancing medical research and improving human health through large-scale genomics research and acceleration of the integration of genomic and other omics data into clinical care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: HealthPartners (myGenetics), Bloomington, Minnesota
Conditions: Genetic Predisposition to Disease, Genetics Disease
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A Study of Contralateral Limb Block
NCT06045936
Recruiting
This research is being done to determine if an anesthetic like Lidocaine, may be effective when injected around the sciatic nerve of the intact limb in patients with limb loss pain on the contralateral side.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/10/2025
Locations: Mayo Clinic Health System - Mankato, Mankato, Minnesota
Conditions: Limb Pain, Phantom
Register for Updates