Minnesota is currently home to 2090 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Pathways 2 Success
NCT06831123
Recruiting
This study involves a 3-arm randomized controlled trial designed to investigate the feasibility and acceptability of three preventive interventions designed to reduce risk for escalations in adolescent conduct problems. High school students identified to be at risk for conduct problems will be randomly assigned to one of three intervention options, including a mindfulness-based program, a mindfulness-based program augmented by a new mobile app, and a life skills program. Assessments related to i... Read More
Gender:
ALL
Ages:
Between 13 years and 17 years
Trial Updated:
03/23/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Conduct Disorder, Oppositional Defiant Disorder
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Short Course Radiotherapy for the Treatment of Patients with Glioblastoma, SAGA Study
NCT05781321
Recruiting
This phase II trial compares the effect of short course radiotherapy (RT) to standard course RT for the treatment of patients diagnosed with glioblastoma (GBM). The researchers want to learn whether the shorter course treatment is non-inferior (not worse than the standard of care), for patients with GBM. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Short course radiotherapy delivers higher doses of radiation over a shorter per... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/23/2025
Locations: Mayo Clinic Health System in Albert Lea, Albert Lea, Minnesota
Conditions: Glioblastoma
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TRE in Type 2 Diabetes (See Food Study 3)
NCT05290246
Recruiting
Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers, including acquiring the necessary knowledge, teaching the intervention, cost of delivery and potential burden on quality of life. In contrast to intentionally restricting calories, time restricted eating (TRE), presents a simplified view of eating focused on restricting the eating window, which allows ad... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/23/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type2Diabetes
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Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
NCT06347133
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo and be evaluated for efficacy and safety.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2025
Locations: University of Minnesota Medical Center, Minneapolis, Minnesota
Conditions: Hypertriglyceridemia
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Circadian Rhythms in Human Adipose
NCT06891534
Recruiting
The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Obesity, Abdominal, Feeding Patterns
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Trial of Cell Based Therapy for DMD
NCT06692426
Recruiting
This is a single-center, single-arm, interventional phase 1 trial to evaluate the safety and tolerability of local injection of induced pluripotent stem cell (iPSC)- derived CD54+ allogeneic muscle progenitor cells in individuals with Duchenne muscular dystrophy (DMD)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Duchenne Muscular Dystrophy
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Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
NCT06378359
Recruiting
The purpose of the study is to determine the effectiveness, safety, and health-care utilization and costs of a preoperative Staphylococcus aureus (SA) screening and decolonization bundle, (5 days of nasal mupirocin ointment, chlorhexidine gluconate (CHG) body wash, and CHG mouth rinse), in eradicating SA carriage compared to other SA decolonization approaches. The study will conduct a single center pilot trial to compare efficacy of different SA decolonization approaches in pre-surgical patients... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: University of Minnesota Medical Center and Clinics, Minneapolis, Minnesota
Conditions: Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
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teleABLE to Reduce Post-Stroke Sedentary Behavior
NCT06312709
Recruiting
The goal of this clinical trial to test whether a remotely delivered behavioral activation-based intervention called "teleABLE" works better than a health education intervention for (1) reducing sitting time and (2) improving health-related quality among adults who were diagnosed with stroke within the past 12 months. Participants in this study will: * Complete questionnaires at Weeks 1, 8, and 24 * Wear an activPAL monitor at Weeks 1, 8, and 24 * Participate in the teleABLE intervention (12 s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: School of Kinesiology, University of Minnesota, Minneapolis, Minnesota
Conditions: Stroke
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Food at Home Study
NCT06286514
Recruiting
The study objective is to develop an accessible home food environment assessment toolkit that includes valid and reliable paper and electronic tools targeting foods known to impact diet-related health that can be user-administered across literacy levels in English and Spanish.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Obesity, Diet, Healthy
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miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial
NCT06285253
Recruiting
The clinical trail will assess the safety of miroliverELAP for the treatment of acute liver failure without underlying chronic liver disease. miroliverELAP is an external liver assist combination product consisting of a single-use MIRO-001 bioengineered liver graft and an extracorporeal blood circuit. miroliverELAP Is intended to support the native (failed) liver for up to 48-hours of continuous treatment to allow time for liver recovery or to identify a transplantable liver.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/21/2025
Locations: University of Minnesota Medical School, Minneapolis, Minnesota
Conditions: Acute Liver Failure, Acute Liver Injury, Drug Induced
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Efficacy of Nerve Blocks for Episodic Migraine
NCT05734625
Recruiting
The purpose of this study is to see how well blocking two to ten of the scalp nerves (that give feeling to the scalp and are painful during migraine headaches) with bupivacaine anesthetic (numbing medication) and low dose methylprednisolone (cortisone-like medicine or steroid) work for treating and preventing migraines. Our hypothesis is that the pain of most episodic migraine headaches can be eliminated and prevented for months by blocking the nerves that give pain sensation during a migraine.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Episodic Migraine
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Epidural Stimulation After Neurologic Damage: Long-Term Outcomes
NCT05705453
Recruiting
This study will evaluate the long-term effect of chronic spinal cord stimulation to restore volitional movement for patients with chronic spinal cord injuries.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/21/2025
Locations: Hennepin County Medical Center, Minneapolis, Minnesota
Conditions: SCI - Spinal Cord Injury
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