There are currently 1289 clinical trials in Cleveland, Ohio looking for participants to engage in research studies. Trials are conducted at various facilities, including Cleveland Clinic, Cleveland Clinic Foundation, Case Western Reserve University and University Hospitals Cleveland Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
CERAMENT G Device Registry
NCT06010433
Recruiting
This is an Observational Device Registry Study of CERAMENT\|G in normal use in accordance with the IFU. It will run for a period of three years from enrolment of the first patient into the Study at each Site, before being subject to review. A Device Registry is a form of observational study that concerns the performance of a device in normal use. It is intended to collect data that is reflective of 'real world' device performance.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Chronic Osteomyelitis, Fracture Related Infection, Diabetic Foot Osteomyelitis
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Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma
NCT04301843
Recruiting
Difluoromethylornithine (DFMO) will be used in an open label, multicenter, study in combination with etoposide for subjects with relapsed/refractory neuroblastoma.
Gender:
ALL
Ages:
31 years and below
Trial Updated:
08/02/2024
Locations: Cleveland Clinic Children's, Cleveland, Ohio
Conditions: Neuroblastoma
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Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
NCT05868668
Recruiting
The purpose of this study to perform a randomized, sham controlled analysis of the effectiveness of both fSWT and rWT in the relief of erectile dysfunction and chronic pelvic pain syndrome.
Gender:
MALE
Ages:
40 years and above
Trial Updated:
07/31/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction, Erectile Dysfunction Due to Arterial Disease, Chronic Pelvic Pain Syndrome, Chronic Prostatitis, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Radiation Therapy
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Pain After Buffered Vs Non Buffered Articaine
NCT06538233
Recruiting
Pain after buffered versus non buffered articaine.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/31/2024
Locations: Clevland Dental Institute, Cleveland, Ohio
Conditions: Pain
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Pain Measured by NRS and EEG in Acute Pulpitis
NCT06526572
Recruiting
The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB). The study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG). By integrating these two m... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/29/2024
Locations: Cleveland Dental Institute, Cleveland, Ohio
Conditions: Acute Pulpitis
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Postoperative Pain After Activation of Irrigant
NCT06528574
Recruiting
The purpose of this research is to analyze the levels of pain after cleaning and shaping in individuals who are receiving root canal therapy using the IVAC irrigation approach, and those who are treated with ultrasonic irrigation techniques, negative pressure irrigation technique and traditional irrigation techniques. PICOTS Question: Does the new Dent's iVac irrigation protocol has an effect on reduction of postoperative pain By enlisting at least 84 suitable individuals who are undergoing t... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/26/2024
Locations: Cleveland Dental Institute, Cleveland, Ohio
Conditions: Pain
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ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
NCT05507216
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Ulcerative Colitis
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Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
ALL
Ages:
All
Trial Updated:
07/25/2024
Locations: RANGER: Cleveland Clinic, Cleveland, Ohio
Conditions: Peripheral Nerve Injuries
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Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery
NCT05992402
Recruiting
The goal of this clinical trial is to learn if new educational program prior to epilepsy surgery can either decrease the risk of cognitive decline after surgery or be a help to those patients who experience a decline after undergoing epilepsy surgery. Participants will participate in 2 individual virtual sessions and 4 virtual group sessions over the course of 5-6 weeks prior to their epilepsy surgery. They will asked to fill out online surveys and questionnaires at various times throughout the... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/24/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Epilepsy
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Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
NCT02227251
Recruiting
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio +1 locations
Conditions: Diffuse Large B-cell Lymphoma
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Implant for Walking After Stroke
NCT05740540
Recruiting
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in stroke survivors. There are two phases in the study: 1) Screening - this phase determines if the individual is a good candidate to receive an implanted system, 2) Implantation, controller development, and evaluation - this phase includes installing the device and setting the individual up for home use, creating advanced controllers for walking and evaluating the effect of the device over sever... Read More
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
07/22/2024
Locations: Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio +1 locations
Conditions: Stroke, Hemiplegia, Gait, Hemiplegic
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Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
NCT06425016
Recruiting
This will be a prospective, obesity-registry based, single-blind randomized controlled trial with a 1:1 allocation ratio. Specific inclusion criteria are all patients eligible to undergo a Laparoscopic sleeve gastrectomy (LSG) based on the current National Institute of Health (NIH) patient selection guidelines. Patients should be able to give consent, be deemed medically-cleared to undergo elective surgery, and tolerate general anesthesia. All enrollments and surgeries in this study will take pl... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/22/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Post Operative Pain, Laparoscopic Sleeve Gastrectomy, Robotic Sleeve Gastrectomy, Obesity, Bariatric Surgery Candidate, Quality of Life
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