Oklahoma is currently home to 943 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Oklahoma City, Tulsa, Norman and Edmond. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Liver Cancer Disparities in American Indian and Alaska Native Persons
NCT05304234
Recruiting
We are performing a pilot and feasibility randomized controlled trial (RCT) of HCC screening by US + AFP every 6 months (n=100), the current standard-of-care, versus aMRI + AFP every 6 months (n=100) for 12 months (i.e. at time 0, 6 and 12 months) among AI/AN patients with cirrhosis or HBV.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/13/2022
Locations: Cherokee Nation Health Service, Tahlequah, Oklahoma
Conditions: Hepatocellular Carcinoma, Cirrhosis, Liver, Hepatitis B
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A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata
NCT05205070
Recruiting
Efficacy and safety of rosnilimab (ANB030) in subjects with moderate-to-severe Alopecia Areata
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2022
Locations: Site 10-106, Tulsa, Oklahoma
Conditions: Alopecia Areata
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Interactive Voice Based Administration of the GAD 7
NCT04990492
Recruiting
This study investigates a new delivery method for the General Anxiety Disorder - 7 (GAD 7), a clinically accepted tool for diagnosing general anxiety disorder. The new tool records auditory responses to the assessment and the study will examine if the instrument is effective at capturing participant depression levels. If proven effective, future studies may investigate if the new format can be used to improve at home clinical care.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2022
Locations: OSU Behavioral Health Clinic, Tulsa, Oklahoma
Conditions: General Anxiety Disorder
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Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for ADHD
NCT05222321
Recruiting
The purpose of this pilot study is to determine the effects of 15 minutes of sensory-play based (SenPlay) intervention on improving focused attention in developmentally appropriate tasks in young children with or at risk for ADHD.
Gender:
All
Ages:
Between 36 months and 71 months
Trial Updated:
04/11/2022
Locations: Sensational Kids, Inc, Yukon, Oklahoma
Conditions: Attention Deficit Hyperactivity Disorder
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Gut Permeability-related Inflammation and Cardiovascular Disease Risk in Normal-weight and Metabolically Healthy Obesity
NCT05308394
Recruiting
The investigators are examining the extent gut permeability explains observed inflammation in normal-weight and metabolically healthy obesity (and potentially cardiovascular disease risk).
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
04/08/2022
Locations: 208 Nancy Randolph Davis, Oklahoma State University, Stillwater, Oklahoma
Conditions: Obesity
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Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
NCT04905836
Recruiting
This is a Phase 2 study to assess COVI-MSC in the setting of current standard of care in hospitalized subjects with RT-PCR confirmed SARS-CoV-2 (COVID-19) infection and acute respiratory distress / acute respiratory distress syndrome.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2022
Locations: Ascension St. John, Tulsa, Oklahoma
Conditions: Covid19
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The RECOVER sUb-study, Which Leverages quaNtitative and Credible Research tOols From Verily, Will providE Assessment measuRes for Depressive Episodes
NCT04753385
Recruiting
The objective of this study is to collect both active and passive data using a wearable, multi-sensor device (Verily Study Watch) and phone application (Mood App) which aims to capture mental health status, in subjects participating in the RECOVER clinical trial (A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2022
Locations: Rivus Wellness & Research Institute, Oklahoma City, Oklahoma
Conditions: Treatment Resistant Depression
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Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors
NCT02013336
Recruiting
This is a Phase 1 study of the combination of two drugs: MM-398 and Cyclophosphamide. The goal is to find the highest dose of MM-398 that can be given safely when it is used together with the chemotherapy drug Cyclophosphamide.
Gender:
All
Ages:
Between 12 months and 20 years
Trial Updated:
03/17/2022
Locations: University Of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Recurrent or Refractory Solid Tumors, Ewing Sarcoma, Rhabdomyosarcoma, Neuroblastoma, Osteosarcoma
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Interbody Systems: Post Market Clinical Follow-up Study
NCT04911257
Recruiting
This is a prospective, multi-center study of subjects who will undergo spinal fusion surgery utilizing Stryker Interbody Systems that require post market clinical follow up (PMCF). The primary study hypothesis for each system is that the mean change in NDI (cervical) or ODI (lumbar) from baseline to Month 12 < -10, that is, the mean improvement exceeds 10 points. In supporting analysis, the same hypotheses will be tested for mean change from baseline to 24 months to demonstrate durability of ef... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/09/2022
Locations: The Spine Clinic of Oklahoma City, Oklahoma City, Oklahoma
Conditions: Degenerative Disc Disease
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Prospective Global Registry for the Study of Chronic Total Occlusion Intervention
NCT02061436
Recruiting
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiated registry is to collect information on treatment strategies and outcomes of consecutive patients undergoing CTO PCI among various participating centers. The information collected will be used to deter... Read More
Gender:
All
Ages:
All
Trial Updated:
03/08/2022
Locations: Oklahoma City VA Medical Center, Oklahoma City, Oklahoma
Conditions: Coronary Artery Disease
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NOVOCART®3D for Treatment of Articular Cartilage of the Knee
NCT01957722
Recruiting
This study is to compare NOVOCART 3D relative to Microfracture for the treatment of knee cartilage defects. Efficacy will be evaluated by both pain and function. Safety will also be evaluated.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/01/2022
Locations: Tulsa Bone and Joint Associates, Tulsa, Oklahoma
Conditions: Articular Cartilage of the Femoral Condyle Between 2-6cm2
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Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC
NCT03257033
Recruiting
The study is a multi-center, un-blinded, randomized control study of subjects with locally advanced pancreatic adenocarcinoma which is unresectable.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2022
Locations: Oklahoma University - Stephenson Cancer Center, Oklahoma City, Oklahoma
Conditions: Locally Advanced Pancreatic Cancer
Register for Updates