Oklahoma is currently home to 945 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Oklahoma City, Tulsa, Norman and Edmond. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Targeted High-definition Transcranial Direct Current Stimulation (HD-tDCS) for Reducing Post-stroke Movement Impairments
NCT05174949
Recruiting
Stroke is the leading cause of serious, long-term disability. The emergence of abnormal muscle synergies following a stroke presents a major limitation to the recovery of independent function. Despite the development of many interventions for movement recovery post-stroke, rehabilitation treatments are minimally effective to the muscle synergy impairment. Previous studies have found that muscle synergy impairment is associated with the damage to the corticospinal tract and the maladaptive recrui... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
10/31/2022
Locations: University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Stroke
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Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes
NCT04725838
Recruiting
The UPGRADE registry will capture long-term, real-world outcomes to understand the effect of Differential Target Multiplexed (DTM®) programming in the Spinal Cord Stimulation (SCS) implanted population on the management of chronic pain, primarily on its use for trunk and/or limb pain. The clinical study is sponsored by Celéri Health and is funded through a financial grant from Medtronic's External Research Program. The registry study will be conducted across approximately 25 centers in the Unite... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2022
Locations: Oklahoma Pain Physicians - Norman, Norman, Oklahoma
Conditions: Chronic Pain
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Diagnostic Accuracy and Safety of DBV1605 for the Diagnosis of Non-IgE Mediated Cow's Milk Allergy in Children
NCT04492683
Recruiting
Study to assess the diagnostic accuracy (sensitivity, specificity, positive and negative predictive value) of DBV1605 for the diagnosis of non-Immunoglobulin E (IgE) mediated cow's milk allergy (CMA) in children with symptoms suggestive of non-IgE mediated CMA.
Gender:
All
Ages:
Between 29 days and 24 months
Trial Updated:
08/09/2022
Locations: Allergy, Asthma & Clinical Research Center, Oklahoma City, Oklahoma
Conditions: Cow's Milk Allergy
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Unidos Against ATOD Use Intervention Trial
NCT03642106
Recruiting
Adolescent alcohol tobacco and drug (ATOD) use is a major public health concern, with rates for Latino middle school youth higher than other ethnic groups. One well-established precursor of adolescent ATOD use is psychosocial stress. The proposed project examines the preliminary efficacy of Unidos to decrease ATOD use among Latino youth in new settlement areas. The goals of this efficacy trial will be achieved by accomplishing two specific aims: (1) Evaluate the potential of the intervention to... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
07/26/2022
Locations: Oklahoma State University-Tulsa, Tulsa, Oklahoma
Conditions: Substance Use
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Analgesic Comparison of PENG/LFCN to FICB for Total Hip Arthroplasty
NCT05477641
Recruiting
This study compares 2 commonly used interventions (regional pain blocks) used in hip arthroplasty for pain control. One of the interventions is newer and not widely established.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
07/25/2022
Locations: SSM Healthcare Bone and Joint Hosptial at St Anthony, Oklahoma City, Oklahoma
Conditions: Comparison or Analgesic Effects of 2 Different Interventional Pain Blocks by Patient Reported Pain Scores, Comparison of Opioid Consumption Between 2 Groups Receiving Different Pain Blocks for Total Hip Arthroplasty
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A Study to Monitor Ambulatory Blood Pressure Monitoring in Hypogonadal Men Treated With Nasal Testosterone Gel
NCT04976595
Recruiting
The purpose of this study is to assess the change in 24-hour ambulatory blood pressure monitoring (ABPM) between baseline (Day 0) and Day 120 following 4 months of testosterone therapy with Natesto.
Gender:
Male
Ages:
Between 18 years and 80 years
Trial Updated:
07/04/2022
Locations: Lynn Health Science Institute, Oklahoma City, Oklahoma
Conditions: Hypogonadism
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A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata
NCT05205070
Recruiting
Efficacy and safety of rosnilimab (ANB030) in subjects with moderate-to-severe Alopecia Areata
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2022
Locations: Site 10-106, Tulsa, Oklahoma
Conditions: Alopecia Areata
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Interactive Voice Based Administration of the GAD 7
NCT04990492
Recruiting
This study investigates a new delivery method for the General Anxiety Disorder - 7 (GAD 7), a clinically accepted tool for diagnosing general anxiety disorder. The new tool records auditory responses to the assessment and the study will examine if the instrument is effective at capturing participant depression levels. If proven effective, future studies may investigate if the new format can be used to improve at home clinical care.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2022
Locations: OSU Behavioral Health Clinic, Tulsa, Oklahoma
Conditions: General Anxiety Disorder
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Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for ADHD
NCT05222321
Recruiting
The purpose of this pilot study is to determine the effects of 15 minutes of sensory-play based (SenPlay) intervention on improving focused attention in developmentally appropriate tasks in young children with or at risk for ADHD.
Gender:
All
Ages:
Between 36 months and 71 months
Trial Updated:
04/11/2022
Locations: Sensational Kids, Inc, Yukon, Oklahoma
Conditions: Attention Deficit Hyperactivity Disorder
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Gut Permeability-related Inflammation and Cardiovascular Disease Risk in Normal-weight and Metabolically Healthy Obesity
NCT05308394
Recruiting
The investigators are examining the extent gut permeability explains observed inflammation in normal-weight and metabolically healthy obesity (and potentially cardiovascular disease risk).
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
04/08/2022
Locations: 208 Nancy Randolph Davis, Oklahoma State University, Stillwater, Oklahoma
Conditions: Obesity
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Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
NCT04905836
Recruiting
This is a Phase 2 study to assess COVI-MSC in the setting of current standard of care in hospitalized subjects with RT-PCR confirmed SARS-CoV-2 (COVID-19) infection and acute respiratory distress / acute respiratory distress syndrome.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2022
Locations: Ascension St. John, Tulsa, Oklahoma
Conditions: Covid19
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Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors
NCT02013336
Recruiting
This is a Phase 1 study of the combination of two drugs: MM-398 and Cyclophosphamide. The goal is to find the highest dose of MM-398 that can be given safely when it is used together with the chemotherapy drug Cyclophosphamide.
Gender:
All
Ages:
Between 12 months and 20 years
Trial Updated:
03/17/2022
Locations: University Of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Recurrent or Refractory Solid Tumors, Ewing Sarcoma, Rhabdomyosarcoma, Neuroblastoma, Osteosarcoma
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