Tennessee is currently home to 1940 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Nashville, Memphis, Knoxville and Chattanooga. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Rare and Atypical Diabetes Network
NCT05544266
Recruiting
RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to: 1. Identify and enroll individuals and families with undiagnosed rare and atypical forms of diabetes. 2. Determine the etiologic basis of the metabolic disorder among individuals and families with novel forms of rare and atypi... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/14/2022
Locations: Vanderbilt University, Nashville, Tennessee
Conditions: Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases
Register for Updates
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
NCT05401357
Recruiting
This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes. Test Product - Bimatoprost ophthalmic solution, 0.01% of Amneal EU, Limited Reference Product - LUMIGAN® (bimatoprost ophthalmic solution) 0.01% of Allergan, Inc.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2022
Locations: Toyos Clinic, Nashville, Tennessee
Conditions: Glaucoma, Open-Angle, Ocular Hypertension
Register for Updates
Spinal Cord Injury Registry - North American Clinical Trials Network
NCT00178724
Recruiting
The NACTN Spinal Cord Injury Registry is a network of clinical centers collecting de-identified data from patients admitted through the Emergency Department of a NACTN center at the time of injury with an initial (first time) spinal cord injury (SCI). Information will be collected on the natural history of SCI and course of treatment through the first 12 months from the date of injury or long as medically indicated. Data collected includes imaging information from CT or MRI scans, neurological a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/22/2020
Locations: Hamid Shah, MD, Nashville, Tennessee
Conditions: Spinal Cord Injury
Register for Updates
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
NCT01088217
Recruiting
The purpose of this study is to investigate inherited genetic factors that play a role in the development of familial pulmonary fibrosis and to identify a group of genes that predispose individuals to develop pulmonary fibrosis. Finding the genes that cause pulmonary fibrosis is the first step at developing better methods for early diagnosis and improved treatment for pulmonary fibrosis. The overall hypothesis is that inherited genetic factors predispose individuals to develop pulmonary fibrosis... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/11/2020
Locations: Vanderbilt University, Nashville, Tennessee
Conditions: Idiopathic Pulmonary Fibrosis, Familial Pulmonary Fibrosis, Idiopathic Interstitial Pneumonia, Familial Interstitial Pneumonia
Register for Updates
Caris Biorepository Research Protocol
NCT01499394
Recruiting
The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2020
Locations: Advantage Clinical Research, Nashville, Tennessee
Conditions: Cancer
Register for Updates
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair
NCT02803957
Recruiting
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Gender:
ALL
Ages:
21 years and above
Trial Updated:
12/04/2019
Locations: St. Thomas, Nashville, Tennessee
Conditions: Mitral Valve Insufficiency
Register for Updates
Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
NCT02040610
Recruiting
This study is being proposed to evaluate the use of moderate hypofractionated proton therapy in low and intermediate risk prostate cancer patients. Quality of life outcomes as well as gastrointestinal and genitourinary early and late toxicities will be analyzed and compared to conventional proton therapy regimens. It is thought that this regimen will produce comparable findings and would result in substantial health care cost savings, as well as, be more convenient for patients.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/03/2019
Locations: Provision Cares Proton Therapy Center Knoxville, Knoxville, Tennessee
Conditions: Prostate Cancer
Register for Updates
Y90 Radioembolization Dose Delivery and Radiation Exposure Assessment
NCT03686709
Recruiting
The objective of this study is to examine critical aspects of radiation exposure, dose delivery, and systemic yttrium-90 (Y90) exposure related to the infusion of Y90 microspheres for treatment of hepatocellular carcinoma (HCC) and other metastatic liver disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2018
Locations: University of Tennessee Medical Center, Knoxville, Tennessee
Conditions: Hepatocellular Carcinoma, Radiation Exposure
Register for Updates