Virginia is currently home to 1852 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Richmond, Charlottesville, Norfolk and Fairfax. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Inova Cardiogenic Shock Registry (INOVA SHOCK)
NCT03378739
Recruiting
To collect retrospective clinical outcomes related to acute decompensated heart failure cardiogenic shock, acute myocardial infarction cardiogenic shock and compare current versus historical survival rates. To collect Inova Heart and Vascular Institute (IHVI) site specific outcomes before and after initiation of the Cardiogenic Shock team on January 1, 2017. To collect outcomes related to implementation of mechanical circulatory support versus no circulatory intervention and type of interventi... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/25/2025
Locations: Inova Fairfax Hospital, Falls Church, Virginia
Conditions: Cardiogenic Shock
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A Modular Phase 1/2 Study with CT7439 in Participants with Solid Malignancies
NCT06600789
Recruiting
This modular, multi-part, multi-arm, Phase 1/2, FIH study allows the evaluation of the safety and tolerability of CT7439, dosed as a monotherapy and in combination with anticancer treatment in participants with solid malignancies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Research site 02, Fairfax, Virginia
Conditions: Solid Malignancies
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NXT Post-Market Clinical Follow-up
NCT06336304
Recruiting
NXT Urodynamics System Post-Market Clinical Follow-up Clinical Investigation to Confirm Ongoing Safety and Performance in Urodynamic Patient Sub-Populations
Gender:
ALL
Ages:
All
Trial Updated:
02/24/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Urinary Incontinence, Urinary Obstruction, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Incontinence, Urge
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Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2
NCT06139458
Recruiting
The investigators aim to determine the effect of cryotherapy wraps plus compression therapy (henceforth referred to as cryocompression) versus cryotherapy wraps alone on the incidence and degree of chemotherapy-induced peripheral neuropathy in patients with gynecologic cancer using a noninferiority design. The investigators also aim to determine the effect of cryocompression versus cryotherapy on patient tolerability and patient and staff satisfaction.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Carilion Clinic, Roanoke, Virginia
Conditions: Gynecologic Cancer, Chemotherapy-induced Peripheral Neuropathy
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A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)
NCT05488340
Recruiting
This is a Phase 2 superiority study of LBP-EC01, a recombinant bacteriophage cocktail, with an initial open-label 3-arm pharmacokinetic (PK) lead-in portion of 30 patients to evaluate the optimal dosing regimen to be used in the subsequent 288 patient blinded portion of the study which will be randomized 1:1 comparing LBP-EC01 + antibiotic versus placebo + antibiotic in patients with a history of prior urinary tract infection (UTI) cased by E. coli. All patients will be required to have an activ... Read More
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
02/24/2025
Locations: Research Site 127, Richmond, Virginia
Conditions: Urinary Tract Infections
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PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure at Inova
NCT05433220
Recruiting
A randomized, single-blind intervention trial to test the comparative effectiveness of an electronic health record best practice advisory system that informs clinicians of guideline-indicated and FDA-approved heart failure medications currently not prescribed to their patients with heart failure versus usual care (no alert and how things are done currently). The purpose of the alert is to stimulate appropriate medication prescription for patients with heart failure and a reduced ejection fractio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Inova Health System, Falls Church, Virginia
Conditions: Heart Failure
Register for Updates
Pediatric Post-Approval Registry
NCT04457154
Recruiting
This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatment of moderate or severe obstructive sleep apnea (OSA). Implanted subjects will be followed for 5 years post-implant.
Gender:
ALL
Ages:
Between 18 years and 21 years
Trial Updated:
02/24/2025
Locations: Children's Hospital of the King's Daughters/East Virginia Medical School, Norfolk, Virginia
Conditions: Obstructive Sleep Apnea
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Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial
NCT04419480
Recruiting
Pilot Prospective Randomized Unblinded Pragmatic Trial of Pulmonary Artery Hemodynamic Monitoring Following Hospitalization for Cardiogenic Shock
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/24/2025
Locations: Inova Fairfax Medical Campus, Falls Church, Virginia
Conditions: Cardiogenic Shock, Heart Failure, Ambulatory Hemodynamic Monitoring
Register for Updates
Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC)
NCT06731413
Recruiting
Evaluate frequency of adverse events that lead to chemotherapy discontinuation in vulnerable older adults with recurrent/metastatic PD-L1 TPS\<50% NSCLC patients who receive reduced dose chemotherapy in combination with immunotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Non-Small Cell Lung Cancer, NSCLC, Advanced Non-Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer
Register for Updates
Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults with Refractory or Unexplained Chronic Cough
NCT06504446
Recruiting
This is a phase 2b, randomized, double-blind, placebo-controlled study investigating the efficacy, safety, and tolerability of Taplucainium Inhalation Powder (NOC-110) once daily in adults with refractory or unexplained chronic cough.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/21/2025
Locations: TPMG Clinical Research Williamsburg, Williamsburg, Virginia
Conditions: Refractory or Unexplained Chronic Cough
Register for Updates
Anti-Inflammatory Lifestyle Intervention for Emerging Adult Cancer Survivors
NCT06442397
Recruiting
To test the feasibility and acceptability of AILI and associated research procedures among emerging adult cancer survivors (EACS, N=16) age 18-29.
Gender:
ALL
Ages:
Between 18 years and 29 years
Trial Updated:
02/21/2025
Locations: Virginia Commonwealth University, School of Medicine, Richmond, Virginia
Conditions: Survivorship
Register for Updates
Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality
NCT06370000
Recruiting
Test feasibility of an oral maintenance strategy for transplant eligible AML patients in first CR who are medically underserved or have a disadvantage in the CDC SDOH domains
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Acute Myeloid Leukemia
Register for Updates