Virginia is currently home to 1823 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Richmond, Charlottesville, Norfolk and Fairfax. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Stroke Thrombectomy and Aneurysm Registry
NCT04994756
Recruiting
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brai... Read More
Gender:
ALL
Ages:
Between 1 year and 120 years
Trial Updated:
12/05/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Stroke, Thromboses, Intracranial, Aneurysm, Brain
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Post-Market Study to Assess iTind Safety in Comparison to UroLift
NCT04757116
Recruiting
The study objective is to evaluate the safety of the iTind device comparied to UroLift.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
12/05/2024
Locations: Potomac Urology Center, Alexandria, Virginia
Conditions: Benign Prostatic Hyperplasia (BPH)
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NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors
NCT04656496
Recruiting
Pediatric cancer survivors are at an increased risk of excessive weight gain and reduced exercise behaviors with the potential for this risk to worsen over time. With over 80% of pediatric cancer patients living to adulthood, many pediatric cancer survivors experience long-term health consequences such as heart disease - the leading cause of death in this population. The purpose of this clinical research study is to teach parents/caregivers skills that will help prevent and reduce the problems... Read More
Gender:
ALL
Ages:
Between 5 years and 14 years
Trial Updated:
12/05/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Obesity, Childhood, Cancer, Survivorship
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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
NCT03887715
Recruiting
Objectives of this study are to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing a reduction in baseline depressive symptom severity, based on multiple depression scale assessment tools at 12 months from randomization.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Carilion Clinic, Roanoke, Virginia
Conditions: Treatment Resistant Depression
Register for Updates
Diagnostic and Therapeutic Applications of Microarrays in Heart Transplantation
NCT02670408
Recruiting
Demonstrate the impact of the Molecular Microscope Diagnostic System as the standard of care for heart transplant patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Virginia Commonwealth University, Division of Cardiology, Richmond, Virginia
Conditions: Cardiac Transplant Disorder
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Study of Onvansertib in Combination with FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants with a KRAS or NRAS Mutation
NCT06106308
Recruiting
The purpose of this study is to assess 2 different doses of onvansertib to select the lowest dose that is maximally effective, and to assess the safety, efficacy, pharmacokinetics, and pharmacodynamics of onvansertib in combination with FOLFIRI + bevacizumab or FOLFOX + bevacizumab in patients with KRAS or NRAS-mutated metastatic colorectal cancer (CRC) in the first-line setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Metastatic Colorectal Cancer, CRC, KRAS/NRAS Mutation
Register for Updates
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
NCT05930210
Recruiting
This Phase 3 study is a randomized, double-blind, vehicle-controlled, multiple-center, parallel study to evaluate efficacy and safety of ENERGI-F703 GEL compared with vehicle control in subjects with Wagner Grade 1 to Grade 2 diabetic foot ulcers. Baseline target ulcer size (\<16 cm2 vs ≥16 cm2 ) will be included as a stratification factor. Subjects will be randomized 1:1 to receive ENERGI-F703 GEL or vehicle control using an interactive web response system for randomization to automatically ass... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: Salem Veterans Affairs Medical Center VAMC, Salem, Virginia
Conditions: Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
Register for Updates
Safety and Effectiveness of the Yaari Extractor for Management of Shoulder Dystocia
NCT05913609
Recruiting
Prospective, multi-center, single arm with historical control, to verify the safety and effectiveness of the Yaari Extractor used by board certified or board eligible U.S. OB/GYN physicians in the management of shoulder dystocia.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: Inova Fairfax Medical Campus, Falls Church, Virginia
Conditions: Shoulder Dystocia
Register for Updates
Insula Neuromodulation for Chronic Neuropathic Pain
NCT05404581
Recruiting
This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/04/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Neuropathic Pain, Chronic Pain
Register for Updates
Advancing Water Security: a Community Participatory School-Based Hydration Intervention
NCT06714929
Recruiting
The goal of this study is to determine the effectiveness and sustainability of a community-participatory hydration intervention over 3 years within a district that has newly installed hydration stations and is operating under a policy designed to enhance heathy hydration practices and promote equitable access to drinking water.
Gender:
ALL
Ages:
4 years and above
Trial Updated:
12/03/2024
Locations: Children's Hospital of Richmond at VCU Healthy Lifestyles Center, Henrico, Virginia
Conditions: Dental Caries, Obesity Prevention
Register for Updates
The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes
NCT06246669
Recruiting
The goal of this clinical trial is to compare the effects of acute aerobic exercise at two different intensities on psychological measures, symptomology, and time to symptom free in collegiate student athletes with concussion. The main questions it aims to answer are: * Does prescribed, acute aerobic exercise influence measures of pain related fear, anxiety, depression, symptoms, and recovery time? * Does the intensity of the exercise prescription also influence the aforementioned outcomes? Pa... Read More
Gender:
ALL
Ages:
Between 18 years and 25 years
Trial Updated:
12/03/2024
Locations: University of Virginia Department of Kinesiology, Charlottesville, Virginia
Conditions: Concussion, Brain
Register for Updates
Sonodynamic Therapy in Patients With Recurrent GBM
NCT06039709
Recruiting
Patients diagnosed with glioblastoma (GBM) are faced with limited treatment options. This pilot study will evaluate the safety and feasibility of combining an investigational drug called 5-ALA with neuronavigation-guided low-intensity focused ultrasound (LIFU) for patients who have recurrent GBM. Focused ultrasound (FUS) can be used to non-invasively destroy tumor tissue while preserving normal tissue. When FUS is combined with 5-ALA, this combinatorial approach is called sonodynamic therapy (SD... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/03/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Recurrent Glioblastoma, Glioblastoma Multiforme, GBM
Register for Updates