Virginia is currently home to 1821 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Richmond, Charlottesville, Norfolk and Fairfax. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
NCT06390085
Recruiting
This study involves imaging the skin movements of surface tissue on the back. A clinician will perform assessment and intervention procedures manually, using manual and light movements of stretch and compression.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/26/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Tissue Pain
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A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors
NCT05765851
Recruiting
This study will evaluate the safety and efficacy of DS-1103a combination therapy in patients with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/26/2024
Locations: NEXT Oncology, Fairfax, Virginia
Conditions: Advanced Solid Tumor, Breast Cancer
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A First-in-human Study of PRTH-101 Monotherapy +/- Pembrolizumab in Subjects With Advanced Malignancies
NCT05753722
Recruiting
The goal of this Open-Label Study is to evaluate the safety and tolerability of PRTH-101 alone or in combination with pembrolizumab in adults with advance or metastatic solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: Next Oncology, Fairfax, Virginia
Conditions: Advanced or Metastatic Solid Tumors
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Theta Burst TMS for Treatment of Methamphetamine Use Disorder
NCT06372288
Recruiting
This study is using Transcranial Magnetic Stimulation (TMS) to determine if interventional psychiatry treatment can help with the treatment of Methamphetamine Use Disorder. Individuals with Methamphetamine Use Disorder will receive 5 consecutive TMS treatment sessions based off of randomization. Participants will be randomized to one of two groups. TMS treatment arm or sham-TMS arm.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
04/24/2024
Locations: Carilion Clinic, Roanoke, Virginia
Conditions: Methamphetamine Abuse
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A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy
NCT05696613
Recruiting
The goal of the Phase 3a part of this clinical trial is to determine the optimal dose that will be used in the Phase 3b part of this clinical trial. The goal of the Phase 3b part is to assess the efficacy of SNP-ACTH (1-39) Gel relative to rituximab in patients with primary membranous nephropathy (PMN) at month 24.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Primary Membranous Nephropathy
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Early Detection of Breast Cancer in Women With Suspicious Mammograms
NCT03147430
Recruiting
This is a non-treatment study. It will not involve the use of any investigational drug or device. Potential participants will be enrolled through direct contact with collaborating clinical sites when the patient's annual 3D mammogram report yields a BIRADS rating of 4-5. The clinical Investigators or a member of their staff will conduct consent discussion once a suspicious mammogram report is identified or if a patient is referred for imaging of a suspicious area in the breast. After consenting... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: Dorothy G Hoefer Comprehensive Breast Center, Newport News, Virginia
Conditions: Breast Cancer
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A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults
NCT06382311
Recruiting
The aim of this study is to evaluate the safety, reactogenicity and immunogenicity of the Flu Pandemic messenger RNA (mRNA) vaccine (including dose-finding and dose-confirmation) administered healthy adults 18 to 85 years of age.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/19/2024
Locations: GSK Investigational Site, Norfolk, Virginia
Conditions: Influenza, Human
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Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors
NCT03996265
Recruiting
This phase III trial studies how well bupropion works in reducing cancer related fatigue in cancer survivors. Bupropion is a drug that is used to treat depression, as well as to help people quit smoking. Cancer and its treatment can cause fatigue. Giving bupropion may improve cancer related fatigue in cancer survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Chesapeake Regional Medical Center, Chesapeake, Virginia
Conditions: Be Diagnosed With Cancer and Have Completed Systemic Therapy
Register for Updates
Focused Ultrasound and Gemcitabine in Breast Cancer
NCT04796220
Recruiting
This study will test the use of focused ultrasound ablation, low-dose gemcitabine (a chemotherapy) and the combination of focused ultrasound ablation plus low-dose gemcitabine in patients with early-stage breast cancers. We will be testing the effects of each of these regimens on cells in the immune system. We hypothesize that the combination of focused ultrasound ablation and gemcitabine will decrease myeloid-derived suppressor cells and will increase T cell activity. We also hypothesize that f... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Breast Cancer, Breast Neoplasms
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Study of Hepatitis Eradication Receiving Protease Inhibitor Administration
NCT03886077
Recruiting
This is a prospective, non-blinded cohort study that will assess the safety, tolerability, and antiviral efficacy of glecaprevir/pibrentasivir therapy given post-discharge to HCV-negative recipients of HCV infected donors. Patients who meet entry criteria will be enrolled while on the transplant waitlist. At the time of transplant, some donors will be HCV positive / NAT positive and some will not be infected. Enrolled patients who receive an HCV negative donor will serve as contemporaneous contr... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: Sentara Norfolk General Hospital, Norfolk, Virginia
Conditions: Coronary Artery Disease, Morality
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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation
NCT01656603
Recruiting
This study will evaluate the safety of infusion of the investigational cord blood units by carefully documenting all infusion-related problems.
Gender:
ALL
Ages:
All
Trial Updated:
04/17/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Infusion Reactions
Register for Updates
Efficacy of a Physical Therapy Intervention Targeting Sitting and Reaching for Young Children With Cerebral Palsy
NCT04230278
Recruiting
The purpose of the proposed project is to compare the efficacy of two fully developed physical therapy interventions in 8-24 months olds with or at high risk of having Cerebral Palsy (CP). Sitting Together And Reaching To Play (START-Play) targets sitting, reaching and motor-based problem solving in infancy to improve global development. Usual Care Physical Therapy (UCPT) focuses on advancing motor skills and preventing impairments.
Gender:
ALL
Ages:
Between 8 months and 24 months
Trial Updated:
04/16/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Cerebral Palsy
Register for Updates