Virginia is currently home to 1851 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Richmond, Charlottesville, Norfolk and Fairfax. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)
NCT04042844
Recruiting
This is a double-blind, saline-controlled, and randomized study with blinded assessments using a single dose. Subjects that have a current diagnosis of chronic lumbar disc disease and meet eligibility criteria will be enrolled. Chronic lumbar disc disease is defined as back and/or radicular pain with degeneration of the disc confirmed by patient history, physical examination, and radiographic measures such as computed tomography (CT), magnetic resonance imaging (MRI), plain film, myelography, di... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/15/2024
Locations: Virginia iSpine Physicians, Richmond, Virginia
Conditions: Lumbar Disc Disease
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Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men
NCT05329480
Recruiting
The purpose of this study is to investigate the impact of creatine supplementation alone or in combination with a moderate session of physical activity on vascular reactivity and heart hemodynamics in elderly men.
Gender:
MALE
Ages:
Between 55 years and 80 years
Trial Updated:
04/13/2024
Locations: Carilion Roanoke Community Hospital, Roanoke, Virginia
Conditions: Cardiac Function and Hemodynamics
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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
NCT05230173
Recruiting
The purpose of this study is to compare the effectiveness and safety of a strategy of switching to an alternative targeted immunomodulator (TIM) therapy to treat to a target of endoscopic remission, versus continuing index TIM in patients with inflammatory bowel disease (IBD) (Crohn's disease or ulcerative colitis \[UC\]) in symptomatic remission with moderate to severe endoscopic inflammation despite optimization of index TIM in a real-world setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Ulcerative Colitis, Crohn Disease
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Quality of Pediatric Resuscitation in a Multicenter Collaborative
NCT02708134
Recruiting
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression release) and patient outcomes. In addition, the investigators will determine the association of post cardiac arrest care with patient outcomes.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
04/12/2024
Locations: Children's Hospital of Richmond at VCU, Richmond, Virginia
Conditions: Cardiac Arrest, Cardiopulmonary Arrest
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STIMIT Activator 1 IDE Pivotal Study
NCT05883163
Recruiting
The study is a prospective, multi-center, randomized, controlled study using adaptive design to assess the evidence of safety and performance of the STIMIT Activator 1 System in the treatment of patients who have been mechanically ventilated for up to 48 hours and are predicted to require additional minimum 48 hours of mechanical ventilation or longer (adding up to MV time approximately 96 hours or longer).
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/11/2024
Locations: University of Virginia Medical Center, Charlottesville, Virginia
Conditions: Diaphragm Issues
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A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Orthofix Spine Devices
NCT05082090
Recruiting
This protocol is designed to study Orthofix regulatory approved and commercially available spine devices to generate Real World Evidence (RWE) of device safety and performance in the treatment of patients with spine injuries and/or disorders following the local medical standard of care. The clinical data generated from this study will support compliance to global regulatory requirements including but not limited to the European Medical Device Regulation (EU MDR) for the applicable devices.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: Tuckahoe Orthopedics, Richmond, Virginia
Conditions: Spinal Disorders/Injuries
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Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: Inova Fairfax Hospital, Falls Church, Virginia
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
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Treatment of Fibromyalgia With the FibroNova Neuromodulation Device
NCT06271746
Recruiting
Fibromyalgia (FM) is a chronic disorder that affects the musculoskeletal system, causing widespread pain, tenderness, and fatigue. It is estimated to affect 1-5% of the population. The primary symptom of fibromyalgia is widespread pain throughout the body, accompanied by tenderness and sensitivity to pressure. Pharmacological treatments include drugs such as antidepressants, anticonvulsants, and painkillers. Another treatment option for fibromyalgia is the use of devices such as Quell. Other no... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/09/2024
Locations: Gershon Pain Specialists, Virginia Beach, Virginia
Conditions: Fibromyalgia
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Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation
NCT05519293
Recruiting
This is a phase I/IIa, open-label, dose-escalation and expansion study to evaluate the safety, tolerability, PK and preliminary anti-tumor activity of H002 when given orally in patients with active EGFR mutation locally advanced or metastatic non-small cell lung cancer (NSCLC). The study will contain two parts: Part A is dose escalation phase (i.e., Phase I) and Part B is dose expansion phase (i.e., Phase IIa).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: NEXT Virginia, Fairfax, Virginia
Conditions: Non-small Cell Lung Cancer
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The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults
NCT05468255
Recruiting
The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consumption of a meal. It is an indicator of insulin resistance (or type 2 diabetes) and impaired glycemic control has been suggested to lead to cardiovascular disease. Endothelial function has been shown to... Read More
Gender:
ALL
Ages:
All
Trial Updated:
04/09/2024
Locations: Old Dominion University, Norfolk, Virginia
Conditions: Glucose Intolerance, Exercise, Vascular Function
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Tremor Retrainer Software Application for Functional Tremor
NCT06257069
Recruiting
The purpose of this clinical trial is to learn about the Tremor Retrainer smartphone application and Simplified Functional Movement Disorder Rating Scale in patients with functional tremor. The main questions the study aims to answer are: 1. Is the Tremor Retrainer application usable for patients and are there signs that it can help functional tremor? 2. Can a televideo administration of the Simplified Functional Movement Disorder Rating Scale give enough information to use this scale via telev... Read More
Gender:
ALL
Ages:
10 years and above
Trial Updated:
04/08/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Functional Movement Disorder, Functional Neurological Disorder, Functional Neurological Symptom Disorder
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A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD
NCT06346600
Recruiting
This is a Prospective, Non-interventional, Multicenter, Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients with Neovascular (Wet) Age-related Macular Degeneration (nAMD). All subject who completed the parent clinical study (NCT06213038 and NCT05986864) will undergo safety and efficacy assessments up to 5 years post study drug injection.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/03/2024
Locations: Wagner Macula & Retina Center, Norfolk, Virginia
Conditions: Neovascular (Wet) Age-related Macular Degeneration
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