There are currently 53 active clinical trials seeking participants for COVID19 research studies. The states with the highest number of trials for COVID19 participants are Florida, Texas, California and New York.
Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19
NCT05228717
Recruiting
This study seeks to define the ultrasound profile of patients with COVID-19, and document the progression of these ultrasound findings to develop prognostication and clinical decision instruments that can help guide management of patient with COVID-19. Primary aims include the development of ARDS, refractory hypoxemia, acute cardiac injury, pulmonary embolism, pneumothorax or death. Secondary aims include potential change in CT and plain film utilization given the use of POCUS, as well as emerge... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2022
Locations: UCLA-Ronald Reagan, Los Angeles, California +3 locations
Conditions: Lung Injury, ARDS, Acute Cardiac Event, Covid19, Ultrasound, Hypoxemia, Acute Respiratory Distress Syndrome
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Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
NCT04905836
Recruiting
This is a Phase 2 study to assess COVI-MSC in the setting of current standard of care in hospitalized subjects with RT-PCR confirmed SARS-CoV-2 (COVID-19) infection and acute respiratory distress / acute respiratory distress syndrome.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2022
Locations: Teradan Clinical Trials LLC, Brandon, Florida +5 locations
Conditions: Covid19
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Use of Monoclonal Antibodies for the Treatment of Mild to Moderate COVID-19 in Non-Hospitalized Setting
NCT04840459
Recruiting
No therapeutic agent is currently approved for the treatment of SARSCoV-2 infection. More importantly, no intervention is currently available to mitigate the progression of disease from mid/moderate to serve particularly in high risk patients. Recognizing this limitation and urgency of finding a treatment for COVID-19, the U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergencyuse of the unapproved product bamlanivimab or casirivimab + imde... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
03/14/2022
Locations: DHR Health Institute for Research and Development, Edinburg, Texas +2 locations
Conditions: Covid19
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Outpatient Liquid Aspirin (OLA)
NCT04937088
Recruiting
The purpose of this study is to obtain reliable and interpretable data to inform future trials regarding our hypothesis that a novel, liquid aspirin formulation can mitigate COVID -19 associated coagulopathy (CAC) . The potential impact is to reduce COVID-19 related hospitalization within 30 days of diagnosis due to (1) pulmonary events including respiratory failure; (2) cardiac events including myocardial infarction and myocarditis (3) venous or arterial thrombotic events; (4) acute renal insuf... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
12/13/2021
Locations: Lsuhsc-No, New Orleans, Louisiana
Conditions: Covid19
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VEText Message Framing and Covid-19 Vaccine Uptake Among at Risk Veterans
NCT04805931
Recruiting
This is a prospective, randomized controlled trial that will evaluate the effectiveness of two different targeted outreach interventions aimed at increasing Covid-19 vaccine uptake. Veterans who are eligible for COVID-19 vaccine receipt by priority status (based on institutional guidelines) will be identified. Veterans must be enrolled into Veterans Health Administration (VHA) care and meet age or illness institutional priority guidelines to be eligible. Veterans eligible for enrollment into the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/25/2021
Locations: VA Puget Sound Health Care System, Seattle, Washington
Conditions: Covid19, Vaccine Refusal
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iCareDx PSS-1 Point-of-Care (POC) Assay for Detection of COVID-19
NCT04937595
Recruiting
Purpose of this clinical investigation is to establish the performance of the iCareDx PSS-1 RT PCR POC Testing Platform which is used to detect COVID-19 in symptomatic patients using the patients saliva. The study focuses on obtaining a minimum of 30 positive and 30 negative test for this study. Results will serve to establish the assay's performance. Symptomatic patients who are being tested for COVID-19 will be enrolled and consented into this study. If the patient consents, 2 saliva specimens... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/22/2021
Locations: Froedtert Health WAC, Wauwatosa, Wisconsin
Conditions: Covid19
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Use of the Interleukin-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection
NCT04363502
Recruiting
In this study Investigators propose to administer clazakizumab to patients with life-threatening COVID-19 infection manifest by pulmonary failure and a clinical picture consistent with a cytokine storm syndrome. This is a single-center randomized, double-blind, placebo-controlled trial in which 30 patients will be enrolled and randomly assigned in a 1:1 ratio to two study arms that will receive clazakizumab at a dose of 25 mg or placebo.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/10/2021
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Covid19
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Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure
NCT04445285
Recruiting
This Phase 2 Randomized Placebo Controlled Trial will determine if administering nebulized Dornase Alpha (rhDNase) to COVID-19 patients with respiratory failure is safe and will reduce 28-day mortality.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/26/2021
Locations: University of South Alabama, Mobile, Alabama
Conditions: Covid19
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Cardiopulmonary Rehabilitation in COVID-19 Longhaulers
NCT04898205
Recruiting
This study will test the efficacy of treadmill exercise combined with supplemental oxygen during exercise and recovery for the treatment of persistent post-acute COVID-19 symptoms. Participants will be pseudo-randomized (stratified by age) to one of four conditions for 8 treatment sessions: 1) treadmill exercise plus supplemental oxygen, 2) treadmill exercise plus air, 3) supplemental oxygen only, 4) air only. All participants will then cross-over and receive 16 additional sessions of treadmill... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2021
Locations: Post-COVID Rehabilitation and Recovery Clinic at H&D Physical Therapy, New York, New York
Conditions: Covid19, Viral Syndrome
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Physical Rehabilitation of COVID-19 Survivors by Heat Therapy
NCT04673318
Recruiting
Older adults and people with underlying medical conditions are at higher risk for developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae. The goal of this proposal is to compare the benefits of home-based lower limb heat therapy to exercise training on cardio-metabolic function and mobility in older adults during their convalescence from hospitalization due to SARS-CoV-2.
Gender:
All
Ages:
Between 55 years and 85 years
Trial Updated:
04/27/2021
Locations: Institute of Applied Life Sciences, Amherst, Massachusetts
Conditions: Covid19, Physical Disability
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The Efficacy and Safety of SCTA01 in Hospitalized Patients With Severe COVID-19
NCT04644185
Recruiting
The study is a multicenter, adaptive, randomized, double-blinded and placebo-controlled Phase II/III trial, and will be conducted globally. The study is comprised of two parts: dose selection (Phase II) and pivotal treatment effect (Phase III).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2021
Locations: SCT study site, Somers Point, New Jersey +6 locations
Conditions: Covid19
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Parkinson's Disease and Experiences Throughout the COVID-19 Pandemic
NCT04720118
Recruiting
The purpose of this research study is to examine the relationship between personal characteristics and satisfaction with care in those diagnosed with Parkinson's disease during the COVID-19 pandemic. Participants will take 4 different surveys regarding their satisfaction with care throughout the duration of the COVID-19 pandemic. The surveys in total should not take more than 30 minutes to complete
Gender:
All
Ages:
18 years and above
Trial Updated:
03/30/2021
Locations: Towson University, Towson, Maryland
Conditions: Parkinson Disease, Covid19, Satisfaction, Patient, Quality of Life
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