There are currently 103 active clinical trials seeking participants for Type 2 Diabetes research studies. The states with the highest number of trials for Type 2 Diabetes participants are California, Texas, Florida and North Carolina.
Effectiveness of the Diabetes Homeless Medication Support (D-HOMES) Program on Diabetes Management
NCT07091487
Recruiting
The goal of this clinical trial is to learn if the Diabetes Homelessness Medication Support (D-HOMES) wellness coaching model is effective for adults who speak English or Spanish, have Type 2 diabetes with an HbA1c at or above 7.5, and have recently experienced homelessness. Researchers will compare a one-time education session about diabetes to 10 wellness coaching sessions to see if there are differences between the groups' health outcomes. The main questions it aims to answer are: * Do D-HOM... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/21/2025
Locations: Hennepin Healthcare Research Institute, Minneapolis, Minnesota
Conditions: Type 2 Diabetes
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Innovative Automated Insulin Delivery System for Type 2 Diabetes
NCT06853990
Recruiting
The goal of this clinical trial is to learn if the twiist insulin delivery system works to treat adults with insulin-treated type 2 diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Scripps Whittier Diabetes Institute, La Jolla, California +23 locations
Conditions: Type 2 Diabetes, Insulin Treated Type 2 Diabetes Mellitus
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A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes
NCT06972472
Recruiting
The main purpose of this study is to see how orforglipron, compared with placebo, helps improve glycemic control in participants with obesity or with overweight and type 2 diabetes. This trial is part of the master protocol study J2A-MC-GZPO. Participation in the study will last about 18 months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: Novak Clinical Research - Tucson - North La Cholla Boulevard, Tucson, Arizona +88 locations
Conditions: Obesity, Overweight, Type 2 Diabetes
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Preventing T2DM After GDM With Immediate Postpartum Screening
NCT06457139
Recruiting
The overall goal of this proposal is to create and test an implementation protocol for in-hospital immediate postpartum diabetes screening for postpartum patients with pregnancies affected by GDM.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/15/2025
Locations: University of Massachusetts Memorial Medical Center, Worcester, Massachusetts
Conditions: Gestational Diabetes, Type 2 Diabetes
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Renal Mechanism of SGLT2 Inhibition
NCT05507892
Recruiting
Canagliflozin is an oral drug which is currently approved for use in patients with type 2 diabetes by the US Food and Drug Administration (FDA). Canagliflozin acts by increasing salt and sugar loss in the urine, and has shown to protect heart, kidney, and blood vessel function in patients with type 2 diabetes. However, it is unknown how canagliflozin protects the kidneys from disease. Therefore, this study plans to learn more about how canagliflozin works to protect against diabetic kidney disea... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/15/2025
Locations: University of Colorado Denver, Aurora, Colorado +1 locations
Conditions: Type 2 Diabetes, Diabetic Kidney Disease
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Type 2 Continuous Glucose Monitoring Academy
NCT06516640
Recruiting
The goal of this clinical trial is to evaluate the Impact of Continuous Glucose Monitoring Academy Education Curriculum Versus Standard Care on Glycemic Outcomes for Youth With Type 2 Diabetes (T2D): * The first aim is to determine how feasible it is to adapt the Continuous Glucose Monitoring Academy curriculum to teach youth with T2D glucose management strategies. * The second aim is to evaluate the effects of the Continuous Glucose Monitoring Academy metrics. * The third aim is to explore the... Read More
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
07/14/2025
Locations: Children's Hospital Los Angeles, Los Angeles, California
Conditions: Type 2 Diabetes
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Personalized Nutrition for Type 2 Diabetes
NCT06784375
Recruiting
This project will compare medical nutrition therapy personalized by continuous glucose monitor (CGM) feedback to control interventions in participants with type 2 diabetes mellitus (T2DM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/14/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type 2 Diabetes
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Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2)
NCT06926842
Recruiting
The main purpose of this study is to investigate efficacy and safety of three doses of petrelintide versus placebo in participants with overweight or obesity and type 2 diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2025
Locations: Cullman Clinical Trials - Family Medicine, Cullman, Alabama +24 locations
Conditions: Overweight, Type 2 Diabetes, Obesity
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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
NCT06897475
Recruiting
The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabetes who are not at HbA1c goal when treated with a stable dose of semaglutide or tirzepatide. Participation in the study will last about 9 months.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/01/2025
Locations: Helios Clinical Research - Phoenix, Phoenix, Arizona +55 locations
Conditions: Type 2 Diabetes
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Extracellular Vesicles, Insulin Action, and Exercise
NCT06546085
Recruiting
Extracellular vesicles (EVs) play a role in obesity-induced insulin resistance and likely impact the development of cardiovascular disease. However, little is known on how EVs affect vascular insulin action in people. The purpose of this study is to understand how EVs play a role in type 2 diabetes related cardiovascular disease. This research will also study if exercise can change how EVs impact blood flow and metabolic health. This study will contribute to designing precision medicine to treat... Read More
Gender:
ALL
Ages:
Between 30 years and 80 years
Trial Updated:
06/30/2025
Locations: Institute for Food, Nutrition, and Health, New Brunswick, New Jersey +2 locations
Conditions: Type 2 Diabetes, Obesity
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Ultrasound Effects on Glycemic Control in T2DM
NCT05354947
Recruiting
This is an open label, exploratory pilot study that will assess the effects of dual site focused pulsed ultrasound treatment on glycemic parameters in subjects with T2DM.
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
06/30/2025
Locations: Yale-New Haven Hospital, New Haven, Connecticut
Conditions: Type 2 Diabetes
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SGLT2i, Hepatic Glucose Production, and SNS
NCT07053293
Recruiting
In this study, we will test the hypothesis that distinct mechanisms account for the SGLT2i-induced stimulation of ketogenesis and lipolysis versus endogenous (hepatic) glucose production in patients with type 2 diabetes (T2D) and type 1 diabetes (T1D), and that the increases in ketone production and lipolysis can be prevented by concomitant administration of the thiazolidinedione pioglitazone. We will conduct five distinct experiments to test this hypothesis in patients with T2D and T1D. Sub-st... Read More
Gender:
ALL
Ages:
Between 30 years and 75 years
Trial Updated:
06/26/2025
Locations: Texas Diabetes Institute/UH, San Antonio, Texas
Conditions: Type 2 Diabetes
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