There are currently 91 active clinical trials seeking participants for Type 2 Diabetes research studies. The states with the highest number of trials for Type 2 Diabetes participants are California, Texas, Florida and North Carolina.
Quantifying Hepatic Mitochondrial Fluxes in Humans
NCT05305287
Recruiting
In this study the investigators will quantitate hepatic mitochondrial fluxes in T2D patients with NAFL and NASH before and after 16-weeks treatment with the insulin sensitizer pioglitazone
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/29/2024
Locations: Texas Diabetes Institute - University Health System, San Antonio, Texas +1 locations
Conditions: Non-Alcoholic Fatty Liver Disease, Type 2 Diabetes, Mitochondrial Metabolism Disorders
Register for Updates
Pharmacist-led Continuous Glucose Monitoring
NCT06572306
Recruiting
This is a pilot study. The goal of this prospective cohort study is to determine impact of pharmacist-led continuous glucose monitoring on glycemic control and health behavior change in people with type 2 diabetes. The main questions it aims to answer are: 1. to assess change in hemoglobin A1c in people with type 2 diabetes using continuous glucose monitoring under a pharmacist-led approach as compared to a pharmacist-led approach utilizing no continuous glucose monitoring (only self-monitoring... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/26/2024
Locations: USF Health Department of Family Medicine - Morsani Center for Advanced Health Care, Tampa, Florida +1 locations
Conditions: Type 2 Diabetes
Register for Updates
Personalized Behavioral Nutrition Intervention in Older AAs With T2D
NCT04533659
Recruiting
The rapid growth rate and unique challenges as a new immigrant group call for a better understanding of the social and health needs of the older Asian Americans (AAs) population. Overwhelming numbers of AAs, a fast-growing first-generation immigrant group, suffer from type 2 diabetes (T2D) and its consequences of poorly controlled blood glucose. For the older AAs, there are higher prevalence rates, worse diabetes control, and higher rates of complications due to limited English proficiency and h... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/14/2024
Locations: The University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Type 2 Diabetes
Register for Updates
Sex Differences in the effecTs of brEaking uP Sedentary Behavior on vascUlar Function in Type 2 Diabetes
NCT05838586
Recruiting
Type 2 diabetes (T2D) confers a high risk of cardiovascular disease (CVD), particularly among older adults who tend to be physically inactive. Prolonged sedentary behavior (SB) has been shown to negatively influence markers of cardiovascular risk (e.g., blood glucose, blood pressure), even among individuals who are physically active. Most studies that have examined the effects of breaking up SB have focused on young healthy males and prioritized glycemic outcomes. Additionally, sex differences i... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
08/01/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type 2 Diabetes, Cardiovascular Diseases
Register for Updates
Glycemic Excursion Minimization (GEM) to Outshine Health Disparities
NCT06236581
Recruiting
The purpose of this study is to see if the GEM intervention is acceptable and helpful to Black adults with type 2 diabetes. The GEM intervention (coaching to reduce carbohydrate intake and increase physical activity after meals, with feedback from a continuous glucose monitor, CGM) might improve blood glucose levels, reduce diabetes distress, and increase empowerment and confidence in managing diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: Georgia Prevention Institute, Augusta, Georgia
Conditions: Type 2 Diabetes
Register for Updates
Developing and Testing a Self-Compassion Tool Kit to Improve the Care of Individuals With Type 2 Diabetes
NCT06398093
Recruiting
There is a high prevalence of anxiety and depression in patients with Type 2 Diabetes (T2D). While past studies demonstrate the potential therapeutic effect of mindfulness-based interventions in patients with T2D, little is understood about the mode of delivery or quantity of the intervention necessary to experience benefits. This project aims to develop and implement a self-compassion tool kit based on the principles of mindfulness and meditation to better understand how self-compassion works t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/15/2024
Locations: University of California, San Diego, San Diego, California
Conditions: Type 2 Diabetes, Diabetes Distress
Register for Updates
SGLT2 Inhibitors, Ketogenesis, and Ketoacidosis
NCT05960656
Recruiting
In this study, we will test the hypothesis that distinct mechanisms account for the SGLT2i-induced stimulation of ketogenesis and lipolysis versus endogenous (hepatic) glucose production in patients with type 2 diabetes (T2D) and type 1 diabetes (T1D), and that the increases in ketone production and lipolysis can be prevented by concomitant administration of the thiazolidinedione pioglitazone. We will conduct five distinct experiments to test this hypothesis in patients with T2D and T1D. STUDY... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/09/2024
Locations: Texas Diabetes Institute/UH, San Antonio, Texas
Conditions: Type 2 Diabetes, Type 1 Diabetes
Register for Updates
Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes
NCT06279637
Recruiting
This study will test the preliminary efficacy of a joint patient/informal caregiver telephone-delivered intervention that includes diabetes education; problem solving around social needs; and behavioral activation for older African Americans with poorly controlled type 2 diabetes by randomizing 100 patient/caregiver dyads to the Joint Home intervention (n=50) and usual care (n=50) arms. The aims of the study are: Aim 1: To test the preliminary efficacy of home-based, joint patient and caregive... Read More
Gender:
ALL
Ages:
Between 50 years and 120 years
Trial Updated:
06/24/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Type 2 Diabetes
Register for Updates
Ketogenic Diet and Diabetes Demonstration Project
NCT06115265
Recruiting
KDDP is a prospective, 12-month pilot study comparing the effects of a novel lifestyle program, the Ketogenic Diet and Diabetes Demonstration Project (KDDP) to those of the National Diabetes Prevention Program (NDDP). KDDP is modeled to mimic the delivery platform of NDPP with the exception that participants in KDDP will be placed on a medically-supervised ketogenic diet, and participants in NDPP will be placed on a low fat diet. The purpose of this study is to compare the metabolic effects of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2024
Locations: University of New Mexico, Albuquerque, New Mexico
Conditions: Type 2 Diabetes, PreDiabetes, Obesity, Ketogenic Dieting
Register for Updates
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction
NCT05593549
Recruiting
The goal of this clinical trial is to examine the role of autophagy on microvascular function in adults with Type 2 Diabetes. The main question it aims to answer are: * Does presence of Type 2 Diabetes reduce autophagy and impair microvascular function? * Does exposure to high glucose impair autophagy and subsequently microvascular function? Participants will undergo 2 study days. The primary outcome will be in vivo microvascular function testing. Following the first study day participants wil... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/30/2024
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Type 2 Diabetes, Healthy Aging
Register for Updates
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
NCT05264727
Recruiting
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
05/28/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Type 2 Diabetes, Obesity
Register for Updates
Continuous Glucose Monitoring for High-Risk Type 2 Diabetes in the Hospital (Cyber GEMS)
NCT05307237
Recruiting
Given the known serious consequences of uncontrolled blood sugars during hospitalization, this research plans to study an alternative seamlessly integrated continuous glucose monitoring (CGM) system in the hospital to test a dynamic and digitized, team-based approach to glucose management in an underserved and understudied, yet high-risk population. A digital dashboard will facilitate real-time, remote monitoring of a large volume of patients simultaneously; automatically identify and prioritize... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: Scripps Mercy Hospital, Chula Vista, California
Conditions: Type 2 Diabetes
Register for Updates