There are currently 103 active clinical trials seeking participants for Type 2 Diabetes research studies. The states with the highest number of trials for Type 2 Diabetes participants are California, Texas, Florida and North Carolina.
PILI 'Āina Household
Recruiting
Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic diseases they experience today. In this project, the investigators will adapt and test an evidence-based multilevel intervention entitled PILI 'Āina to improve the self-management of prevalent cardiometabolic diseases and reduce risk factors for developing new diet-rela... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2025
Locations: Kula no nā Po'e Hawai'i, Honolulu, Hawaii +1 locations
Conditions: Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Recruiting
The purpose of this study is to determine if use of a nonmydriatic fundus camera using autonomous artificial intelligence software at the point of care increases the proportion of underserved youth with diabetes screened for diabetic retinopathy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
05/27/2025
Locations: Johns Hopkins Pediatric Diabetes Center, Baltimore, Maryland
Conditions: Type 1 Diabetes, Type 2 Diabetes, Cystic Fibrosis-related Diabetes
Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis
Recruiting
The overall aim of this study is to investigate the effects of exercise on the amount of glucose that is made by the liver in people with and without Type 2 diabetes (T2D) and hepatic steatosis (fatty liver).
Gender:
ALL
Ages:
Between 25 years and 55 years
Trial Updated:
05/20/2025
Locations: AdventHealth Translational Research Institute, Orlando, Florida
Conditions: Type 2 Diabetes, Hepatic Steatosis
Enhancing Diabetes Care: Exposome &Amp; Sensors
Recruiting
The study aims to integrate various data types, such as electronic health records, wearable device data, and environmental data, to create a comprehensive, personalized diabetes care model. The study will focus on people with type 2 diabetes living in specified vulnerable zip codes.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/16/2025
Locations: University of Illinois - Chicago, Chicago, Illinois +1 locations
Conditions: Type 2 Diabetes
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
Recruiting
SGLT2 inhibitors have demonstrated to mitigate cardiorenal risk in people with type 2 diabetes and are likely to play an increasingly large role in the treatment of patients with diabetes, chronic kidney disease and hypertension. Yet the underlying mechanisms of its protective effects are incompletely understood and the salutary effect may be altered by dietary factors such as sodium intake. Therefore, carefully designed mechanistic trials are needed to better understand the interplay between er... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/13/2025
Locations: Childrens hospital colorado, Denver, Colorado +1 locations
Conditions: Type 2 Diabetes
Pilot RCT Evaluating Clinical Outcomes of Using Undermyfork Mobile App With Dexcom G7
Recruiting
This study aims to determine if adding using a mobile diabetes-related health application with CGM device yields significant benefits, contributing to our understanding of the potential advantages and informing future diabetes care practices. The rationale for testing CGM with Undermyfork in individuals with T2D stems from the potential benefits of real-time glucose monitoring and personalized dietary tracking in improving glycemic control and reducing diabetes-related complications. Unlike stan... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/12/2025
Locations: Scripps Whittier Diabetes Institute, La Jolla, California
Conditions: Type 2 Diabetes
ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community
Recruiting
The purpose of this project is to examine the feasibility/acceptability of a one-day Acceptance and Commitment Therapy + Lifestyle Education group intervention paired with 12-weeks of Continuous Glucose Monitoring for patients with type 2 diabetes (T2D) living in rural communities. This study is being designed as a randomized control trial (RCT) comparing ACT+LE+CGM to LE+CGM to LE. The ultimate goal of this line of research is that a community-wide intervention of Acceptance and Commitment Ther... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Sam Houston State University College of Osteopathic Medicine, Conroe, Texas
Conditions: Type 2 Diabetes
Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
Recruiting
A Randomized Control Trial (RCT) with 1:1 randomization of adults newly diagnosed with type 2 diabetes (T2D) to Routine Care (RC) and RC + Glycemic Excursion Minimization (RC+GEM); a program that provides RC in addition to continuous glucose monitors (CGM) within a structured, self-directed, and personalized lifestyle program called GEM. Our hypothesis is that RC+GEM will: 1) reduce hemoglobin A1c as much or more, 2) require less diabetes medication, 3) cost less, and 4) have more secondary bene... Read More
Gender:
ALL
Ages:
Between 30 years and 80 years
Trial Updated:
05/05/2025
Locations: University of Colorado Department of Family Medicine, Aurora, Colorado +1 locations
Conditions: Type 2 Diabetes
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
Recruiting
This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents. The hypothesis of this study is that adolescents at risk for metabolic disease have enhanced MiMo related activities leading to insulin resistance.
Gender:
ALL
Ages:
Between 14 years and 18 years
Trial Updated:
05/03/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Type 2 Diabetes, Insulin Resistance, Obesity, Metabolic Disease, PreDiabetes
Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED
Recruiting
The goal of this clinical trial is to improve the processes of Type 2 Diabetes (T2D) care coordination and treatment in the emergency department (ED) by utilizing clinical decision support mechanisms in the electronic health record (EHR). The main question is whether electronic prompts triggered by hyperglycemia and elevated A1c results in providers providing earlier treatments and faster time to subsequent primary care appointment and greater reduction in hemoglobin A1c (HA1c). ED clinicians w... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
05/03/2025
Locations: Rutgers, Robert Wood Johnson Hospital, New Brunswick, New Jersey
Conditions: Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM), Hyperglycemia, Insulin Dependent Diabetes
THC Effects on Glucose in Type 2 Diabetes
Recruiting
This study will examine the effects THC has on Glucose Metabolism and Endothelial Functioning in participants with Type 2 Diabetes. The participants will complete blood tests and tests to measure energy expenditure, CVD risks, and glucose metabolism. These tests will be performed prior to start of treatment and again after 2-weeks of treatment with the THC or placebo.
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
05/02/2025
Locations: UC San Diego Altman Clinical & Translational Research Institute, La Jolla, California
Conditions: Type 2 Diabetes
Health Without Barriers/Salud Sin Barreras- Northern Colorado
Recruiting
The overarching goal of this work is to address the limited access to evidence-based health behavior and lifestyle interventions for youth and families most impacted by preventable chronic diseases, including obesity and type 2 diabetes. In the current project, we implement a small single-arm pilot and feasibility trial of Health Without Barriers/Salud Sin Barreras (HWB/SSB), a culturally-adapted, whole-family intensive health behavior and lifestyle intervention to 11-19-year-old adolescents and... Read More
Gender:
ALL
Ages:
11 years and above
Trial Updated:
04/29/2025
Locations: Colorado State University, Fort Collins, Colorado
Conditions: Lifestyle Risk Reduction, Adolescent Health, Family Health, Cardio-metabolic Health, Mental Health, Wellness Program, Type 2 Diabetes, Obesity, Adolescent