Connecticut is currently home to 1245 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
BXCL501 for Agitation in Schizophrenia
NCT03708315
Recruiting
Agitation is characterized by excessive motor or verbal activity, irritability, uncooperativeness, threatening gestures, and, in some cases, aggressive or violent behavior. While agitation may have various underlying causes, patients with schizophrenia are especially vulnerable to acute episodes of agitation, especially during exacerbation of disease, and clinicians do not always diagnose these episodes early enough. Agitation associated with psychosis is a frequent reason for emergency departme... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/06/2024
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Schizophrenia, Schizoaffective Disorder
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Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery
NCT06445413
Recruiting
The goal of this clinical trial is to evaluate the feasibility and acceptability of a 10-wk hybrid Tai Chi (TC) program with in-person classes and online TC videos among 24 physically inactive adults who are seeking metabolic and bariatric surgery (MBS) in a single-arm trial. The aims are: Aim 1: Feasibility: To evaluate whether TC is feasible, defined as a mean attendance rate of ≥70% in-person TC classes attended. Aim 2: Acceptability: To evaluate whether TC is acceptable, defined as a mean... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/04/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Obesity
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Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Bronchiolitis Acute Viral
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Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
NCT05753059
Recruiting
Randomized placebo-controlled, double-blind, double-dummy, crossover design testing combinations placebo/placebo, bendroflumethiazide/placebo, amiloride/placebo, and bendroflumethiazide/amiloride added to bumetanide.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Failure
Register for Updates
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
NCT05313165
Recruiting
A prospective, single-arm, multi-center study designed to gather additional information on the LimFlow System.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/31/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Critical Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
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OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?
NCT05911646
Recruiting
The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA). Our hypothesis is that in children with mild OSA there is significant conflict with parental decision-making; in the absence of significant sleep apnea, there is limited research regarding comparative efficacy of various treatment options. The impact of a QOL questionnaire can be a significant deciding factor and may... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
05/30/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Apnea, Obstructive Sleep, Obstructive Sleep Apnea
Register for Updates
Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy
NCT05730309
Recruiting
The objective of the proposed project is to quantify the prevalence and disparities of undiagnosed left ventricular hypertrophy (LVH) in Emergency Department (ED) patients with persistently elevated asymptomatic BP, and to measure the effect of disclosure, education, and expedited referral on 3-month outpatient follow-up and treatment rates for ED patients with newly diagnosed LVH by POCUS. Additionally, investigators will create a database of annotated clips for future development of a machine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Left Ventricular Hypertrophy
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Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder
NCT06142955
Recruiting
This study will assess clinical and behavioral measures along with electroencephalogram (EEG), event-related potentials (ERPS), and eye-tracking (ET) prior to and following a single intermittent Theta Burst Stimulation (iTBS) session to provide preliminary insight into the potential of TMS as an intervention for depression in individuals with Autism Spectrum Disorder (ASD).
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
05/21/2024
Locations: Yale Psychiatric Hospital, New Haven, Connecticut
Conditions: Autism Spectrum Disorder
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Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant
NCT05203965
Recruiting
The purpose of this study is to evaluate the role of Mavoglurant in clarifying the neurobiology of alcoholism risk. This is a one-site, randomized, within subjects, counterbalanced double-blind study of a single dose (200mg) of Mavoglurant and placebo.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/21/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Familial Alcoholism Vulnerability
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OssDsign® Spine Registry Study ("Propel")
NCT05329129
Recruiting
The purpose of this multi-center, prospective, observational registry is to gather information on the clinical outcomes and real-world use of commercially available bone graft substitutes manufactured by OssDsign® AB, in patients who require spine fusion.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
05/20/2024
Locations: Orthopedic Associates of Hartford, Hartford, Connecticut
Conditions: Degenerative Disc Disease, Spinal Stenosis
Register for Updates
Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)
NCT04474223
Recruiting
Fetal complete (i.e., third degree, 3°) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally associated with maternal anti-Ro autoantibodies and results in death in a fifth of cases. To date treatment of 3° AVB has been ineffective in restoring normal rhythm (NR) which may be because current surveillance is limited to once- weekly fetal echocardiograms. It is hypothesized that there may be a vital transition p... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: AVB - Atrioventricular Block, Fetal AVB
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The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)
NCT06412172
Recruiting
Recurrent respiratory papillomatosis (RRP) is an orphan disease that affects approximately 20,000 people in the United States and is caused by infection with human papillomavirus (HPV) types 6 and 11. Since RRP is an orphan disease, it is an understudied disease entity with correspondingly few treatment options. The investigators hypothesize that by understanding the biology of RRP and the failed host immune responses against HPV, novel and rational therapies can be developed. This study will ex... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/15/2024
Locations: Yale School of Medicine, New Haven, Connecticut
Conditions: Recurrent Respiratory Papillomatosis, Pulmonary Neoplasm
Register for Updates