Connecticut is currently home to 1246 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)
NCT06412172
Recruiting
Recurrent respiratory papillomatosis (RRP) is an orphan disease that affects approximately 20,000 people in the United States and is caused by infection with human papillomavirus (HPV) types 6 and 11. Since RRP is an orphan disease, it is an understudied disease entity with correspondingly few treatment options. The investigators hypothesize that by understanding the biology of RRP and the failed host immune responses against HPV, novel and rational therapies can be developed. This study will ex... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/15/2024
Locations: Yale School of Medicine, New Haven, Connecticut
Conditions: Recurrent Respiratory Papillomatosis, Pulmonary Neoplasm
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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
NCT04373564
Recruiting
This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA. The study aims to create detailed images of the organs and tissue of the human body during x-ray, CT-scan or MRI investigations, doctors are using contrast media (a kind of dye) which can be given to patients by injection into a blood vessel or by mouth. In this study researchers want to find out whether so called gadolinium-based contrast agents (G... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/15/2024
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: Motor Function, Cognitive Function, Contrast Media
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Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population
NCT05260047
Recruiting
The main goal of this current study is to develop and optimize methods for increasing access to, uptake of, and engagement in MAT (Medication Assisted Treatment) among communities of color.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: Mount Aery Baptist Church, Bridgeport, Connecticut
Conditions: Substance Use, Mental Health Issue, Opioid Use, Medication Assisted Treatment
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Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
ALL
Ages:
0 years and above
Trial Updated:
05/14/2024
Locations: University of Connecticut Health, Farmington, Connecticut
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
Register for Updates
A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
NCT05543616
Recruiting
The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called variant-adapted BNT162b2 RNA-based vaccine) in healthy children. The trial is divided into 5 individual studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies will receive study vaccine as a shot depending on what group they are in. * Substudy A design: Phase 1 includes participa... Read More
Gender:
ALL
Ages:
Between 6 months and 11 years
Trial Updated:
05/13/2024
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: SARS-CoV-2 Virus, Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19
Register for Updates
Transitioning Emotionally and Academically to Middle School Successfully (TEAMSS)
NCT05145387
Recruiting
Excessive anxiety is a common problem that severely impairs short and long term academic functioning. The transition to middle school (MS) results in increases in anxiety and decreases in academic functioning. Students with anxiety in particular, due to their vulnerability to school-based stressors, are at risk for social, emotional and academic failure during the transition to MS. Unfortunately, the majority of these students do not get identified. Reducing student anxiety has been associated w... Read More
Gender:
ALL
Ages:
Between 9 years and 13 years
Trial Updated:
05/13/2024
Locations: UConn Health, West Hartford, Connecticut
Conditions: Anxiety Disorders
Register for Updates
Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT
NCT01203085
Recruiting
The primary goal of this project is to develop and test a Charcot Marie Tooth disease (CMT) Pediatric Scale for use in evaluation in natural history CMT study.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
05/09/2024
Locations: University of Connecticut/Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Charcot Marie Tooth Disease
Register for Updates
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
NCT01193088
Recruiting
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
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Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
NCT01193075
Recruiting
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C). The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: University of Connecticut/Connecticut Children's Medical Center, Hartford, Connecticut
Conditions: Charcot Marie Tooth Disease
Register for Updates
PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
Register for Updates
Father-Focused Intervention for Reducing Family Violence and Symptoms in Children
NCT06074068
Recruiting
The goal of this clinical trial is to test the efficacy of Fathers for Change (F4C) compared to standard Batterer Intervention for fathers with a history of Intimate Partner Violence. The main question\[s\] it aims to answer are: 1. Is F4C more efficacious than standard BIP in reducing family violence and child mental health impairment? 2. What are the trajectories of therapeutic change targets across interventions? 3. Does father's emotion regulation and reflective functioning mediate the rela... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Yale, New Haven, Connecticut
Conditions: Intimate Partner Violence, Child Maltreatment
Register for Updates
Dual Reinforcement Contingency Management for Alcohol Use Disorders
NCT04064463
Recruiting
Phosphatidylethanol (PEth) is a direct biomarker of alcohol that can detect moderate to heavy drinking with high sensitivity and specificity over 3-week periods. Reinforcing negative PEth results alongside attendance may increase the proportion of participants who respond to CM during and post treatment. In the proposed study, the investigators will collect PEth samples every 3 weeks for 12 weeks in 150 participants initiating outpatient treatment for alcohol use disorders. Using a two-group ran... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: The Village, Hartford, Connecticut
Conditions: Alcohol Use Disorder, Contingency Management
Register for Updates