Connecticut is currently home to 1207 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New Haven, Hartford, Farmington and Stamford. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF
NCT05639556
Recruiting
The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will provide detailed data regarding the nutrition and body composition within this Cystic Fibrosis population and also provide a baseline evaluation for use of these biomarkers in the future studies inclu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: Cystic Fibrosis
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Meals 4 Moms: A Multilevel Community-based Lifestyle Intervention for GDM
NCT06227247
Recruiting
The goal of the project is to conduct a pilot feasibility randomized trial comparing a community-based lifestyle intervention called Meals for Moms (M4M) versus the usual care for pregnant persons diagnosed with gestational diabetes (GDM). Participants will be randomly placed into the usual care (UC) comparison group or the M4M healthy living program, which includes continued GDM education, physical activity level monitoring, and delivery of medically-tailored GDM meals. The trial will assess if... Read More
Gender:
FEMALE
Ages:
Between 18 years and 49 years
Trial Updated:
02/07/2024
Locations: UConn Health, Farmington, Connecticut
Conditions: Gestational Diabetes
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Alcohol-ROC-Training
NCT05491551
Recruiting
The goal of the proposed study is to examine whether brief training in regulation of craving (ROC-T) affects alcohol drinking. The study will consist of a basic screening (phone and online), and in person visit to determine eligibility and conduct pre-intervention baseline assessments, 1-4 training (ROC-T) visits, a post-intervention assessment visit, and 1-2 phone/online follow up assessments.The two active conditions of ROC-T are based on cognitive-behavioral treatments (CBT) and mindfulness-b... Read More
Gender:
ALL
Ages:
Between 18 years and 26 years
Trial Updated:
02/07/2024
Locations: Yale University, New Haven, Connecticut
Conditions: Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
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Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors
NCT03863145
Recruiting
Subjects will undergo baseline evaluation and an assessment of extent of disease. Subjects in Part 1 (Dose Escalation) will receive escalating doses of CB-03-10 based on a modified Fibonacci schema using a standard oncology 3+3 study design to define an MTD and a RP2D. Plasma PK samples will be collected at predetermined timepoints for all subjects. Subjects in Part 2 (Dose Expansion) of the study will receive CB-03-10 at the RP2D determined in the Part 1 of the study. The indications included... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Yale Cancer Center, New Haven, Connecticut
Conditions: Advanced Refractory Solid Tumors, Subjects Considered Likely to Respond to CB-03-10
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Posture Correction in Cubital Tunnel Syndrome
NCT06095011
Recruiting
The primary objective of this study is to determine whether the UpRight Go posture trainer reduces the symptoms of cubital tunnel syndrome in patients who have not had corrective surgery, as determined by improvements in VAS scores for pain, numbness, and weakness.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Cubital Tunnel Syndrome
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Mind Body Program Vascular
NCT05757752
Recruiting
The purpose of the current study is to conduct a proof-of-concept test regarding the delivery of a Mind Body Program for vascular disease, focusing on support for depression, stress, and adherence, as part of patients' chronic disease management for peripheral artery disease (PAD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/25/2024
Locations: Yale New Haven Health Hospital, New Haven, Connecticut
Conditions: Peripheral Arterial Disease, Peripheral Vascular Diseases
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Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma
NCT05226494
Recruiting
Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be effective in heterogeneous, treatment-resistant tumors such as Glioblastoma. fb-PMT also is actively transported across the blood-brain barrier into the brain. This study is being conducted to determine the dose level for further clinical development of fb-PMT to treat recurrent Glioblastoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/25/2024
Locations: Smilow Cancer Hospital, New Haven, Connecticut
Conditions: Glioma, Malignant
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Bridgeport Hospital, Bridgeport, Connecticut
Conditions: NASH - Nonalcoholic Steatohepatitis
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Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique (STABILISE)
NCT03707743
Recruiting
The aim of the study is to evaluate results of patients treated with the STABILISE technique for acute/subacute aortic dissection. Results and postoperative events are reported in accordance with the current reporting standards for endovascular aortic repair prepared and revised by the Ad Hoc Committee for Standardized Reporting Practices in Vascular Surgery of The Society for Vascular Surgery/American Association for Vascular Surgery
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Aortic Dissection
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BlueWind RENOVA iStim™ System for the Treatment of OAB
NCT03596671
Recruiting
The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
12/29/2023
Locations: Norwalk Urology, Norwalk, Connecticut
Conditions: Treatment of Patients Suffering From Overactive Bladder (OAB)
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Etomidate Versus Propofol in CABG Surgery
NCT06068764
Recruiting
The objective of this single-blinded randomized controlled interventional clinical trial is to learn about the efficacy and long-term safety of etomidate compared to propofol as an anesthesia induction agent in patients undergoing coronary artery bypass graft (CABG) surgery. The primary aim of this study is to determine whether patients receiving etomidate or propofol exhibit similar requirements for vasopressor or ionotropic agents during both the intraoperative and postoperative periods. To a... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/27/2023
Locations: Hartford Hospital, Hartford, Connecticut
Conditions: Coronary Artery Disease
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Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
NCT04591392
Recruiting
Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect
Gender:
ALL
Ages:
84 years and below
Trial Updated:
12/21/2023
Locations: Yale University, New Haven, Connecticut
Conditions: Heart Septal Defect, Heart Septal Defects, Atrial, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases, Congenital Abnormalities
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