Kansas is currently home to 943 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Wichita, Kansas City, Overland Park and Topeka. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Pharmacogenomic Modulators of Impaired Exercise Adaptation in Statin Users
NCT04636138
Recruiting
HMG-CoA reductase inhibitors (statins) have beneficial effects (prevent stroke, heart attack) but also some bad ones (block some good effects of exercise). Individuals have genetic variations in proteins that metabolize/transport statins. The investigators hypothesize that these variations modulate the relationship between statin use and lack of benefit from exercise. The investigators will test this by having statin-users do supervised exercise for 6 weeks, measuring the cardiorespiratory fitne... Read More
Gender:
All
Ages:
Between 35 years and 65 years
Trial Updated:
11/16/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: HMG-CoA Reductase Inhibitor Toxicity
Register for Updates
Natural History of COVID-19-Related Atrial Fibrillation
NCT04830774
Recruiting
The unCOVer-AF prospective, multicenter registry aims at determining the natural history of atrial fibrillation (AF) via continuous cardiac rhythm monitoring in patients with a first arrhythmic episode during COVID-19 hospitalization.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2021
Locations: Kansas City Heart Rhythm Institute, Overland Park, Kansas City, Kansas
Conditions: COVID-19, Atrial Fibrillation New Onset
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A Trial Evaluating the Safety and Immunogenicity of 3 COVID-19 SARS-CoV-2 RNA Vaccines in Healthy Adults
NCT05037097
Recruiting
This is a Phase 1/2, randomized, observer-blind study in healthy adults. The study will evaluate the safety, reactogenicity, and immunogenicity of 3 SARS-CoV-2 self-amplifying RNA vaccine candidates against COVID-19 in adults previously vaccinated and not previously vaccinated against SARS-CoV-2.
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
11/10/2021
Locations: Arcturus Investigational Site 202, Wichita, Kansas
Conditions: COVID-19, SARS-CoV-2 Infection, Corona Virus Infection
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LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors
NCT04979156
Recruiting
Conventional monopolar or bipolar transurethral resection of bladder tumors is the most common method for resection of a bladder mass. En bloc resection has demonstrated success in the literature utilizing different techniques and lasers, including utilizing the Ho:YAG and Tm:YAG lasers. A recent metanalysis revealed several benefits to laser en bloc resection including less complications and lower recurrence rate.22 Subsequently, laser technology has also advanced with the development of a supe... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/04/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Bladder Cancer, Surgery
Register for Updates
Post COVID-19 Biorepository
NCT04885504
Recruiting
Establish a biorepository, clinical data registry, and radiographic image database from individuals who were COVID positive at one time and are being seen for outpatient follow-up or a separate study visit.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Coronavirus Infection
Register for Updates
Continuous Monitoring and Control of Hypoglycemia
NCT03340831
Recruiting
Evaluate safety of non-adjunctive CGM use in CGM naive participants.
Gender:
All
Ages:
2 years and above
Trial Updated:
09/17/2021
Locations: Cotton O'Neil Clinical Research, Topeka, Kansas
Conditions: Diabetes
Register for Updates
Prospective US Radiofrequency SUI Trial
NCT04720352
Recruiting
PURSUIT: Prospective US Radiofrequency SUI Trial (VI-17-06) is a prospective, randomized, sham controlled, double blind study in premenopausal women with stress urinary incontinence. The study will be conducted in 390 subjects, randomized 2:1 with active or sham treatment. Study duration is 12 months post treatment. The primary objective is to evaluate the efficacy of the Viveve treatment, SUI protocol, in improving mild to moderate stress urinary incontinence (SUI), assessed using the 1-hour Pa... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/19/2021
Locations: Cypress Medical Research Center, LLC, Wichita, Kansas
Conditions: Urinary Incontinence, Stress
Register for Updates
Function of Circulating Exosomes in Sepsis-induced Immunosuppression
NCT04979767
Recruiting
This is a single-center prospective bio-specimen analysis and observational study aiming to define immune pathways disrupted in bacterial sepsis and to identify clinically useful biomarkers of immune status.
Gender:
All
Ages:
50 years and above
Trial Updated:
07/16/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Sepsis, Septic Shock, Sepsis Syndrome, Sepsis Bacterial, Sepsis, Severe, Sepsis Bacteremia
Register for Updates
Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: Cypress Medical Research Center, Wichita, Kansas
Conditions: Female Sexual Arousal Disorder
Register for Updates
Pulmonary Hypertension Biorepository and Registry
NCT04808596
Recruiting
Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/27/2021
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Pulmonary Hypertension, Pulmonary Arterial Hypertension, Pulmonary Hypertension Due to Left Heart Disease, Pulmonary Hypertension, Primary, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Pulmonary Hypertension, Primary, 4, Pulmonary Hypertension, Primary, 2, Pulmonary Hypertension, Primary, 3, Chronic Thromboembolic Pulmonary Hypertension
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Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.
NCT04730700
Recruiting
The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Chronic Low-back Pain
Register for Updates
Early PKD Observational Cohort Study
NCT02936791
Recruiting
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being develop... Read More
Gender:
All
Ages:
Between 4 years and 35 years
Trial Updated:
05/06/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Polycystic Kidney Disease
Register for Updates