Michigan is currently home to 2186 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Cephea Early Feasibility Study
Recruiting
The objective of this study is to evaluate the preliminary safety and effectiveness of the Cephea Mitral Valve System for the treatment of symptomatic patients with mitral valve disease (including mitral regurgitation, mitral stenosis and mixed mitral valve disease) in whom transcatheter therapy is deemed more appropriate than open heart surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/20/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Mitral Regurgitation
Study to Evaluate Efficacy, Safety and Tolerability of HM15211(efocipegtrutide) in Subjects
Recruiting
This study is a phase 2 study to Evaluate Efficacy, Safety and Tolerability of HM15211 Treatment for 12 Months in Subjects with Biopsy Confirmed NASH
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/20/2025
Locations: Henry Ford Hospital, Detroit, Michigan
Conditions: NASH - Nonalcoholic Steatohepatitis
A Study to Investigate the Immunogenicity, Reactogenicity, and Safety of mRNA-1083 (Influenza and COVID-19) Vaccine in Adults ≥18 to <65 Years of Age
Recruiting
The purpose of this study is to evaluate the immunogenicity, reactogenicity, and safety, of mRNA-1083 multicomponent influenza and COVID-19 vaccine in adults ≥18 to \<65 years of age.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
03/19/2025
Locations: DM Clinical Research - Detroit, Southfield, Michigan
Conditions: Influenza, SARS-CoV-2
Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain
Recruiting
A randomized study to determine safety and efficacy of single subcutaneous (SC) administration of HAL treatment in patients with CINP.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Profound Research at OMG Division of Clinical Hematology and Medical Oncology, Farmington, Michigan
Conditions: Chemotherapy Induced Neuropathic Pain
Michigan Men's Diabetes Project III(MenDIII): Mind and Motion
Recruiting
The Michigan Men's Diabetes Project III: Mind \& Motion is an 7-month pilot randomized clinical trial. The investigators are looking to recruit 80 Black men with type 2 diabetes (T2D) (need to have diagnosis for at least one year) that are over the age of 18. Participants also must be under the care of a physician for their diabetes, self report an Hemoglobin A1c (A1C) of 7.0% or more in the last year, be willing to participate in study events (weekly physical activity, exercise and Cognitive Be... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Diabetes Mellitus, Type 2, Depressive Symptoms, Depression
Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer
Recruiting
This is a Phase 1/2, open-label, randomized, dose finding and dose expansion study to evaluate the safety, preliminary efficacy, and PK of gedatolisib in combination with darolutamide in subjects with mCRPC.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan
Conditions: mCRPC (Metastatic Castration-resistant Prostate Cancer), Genital Diseases, Male, Urogenital Diseases, Male, Prostatic Disease, Prostatic Neoplasms, Castration-Resistant, Prostate Cancer
Harmony TPV Post-Approval Study
Recruiting
The purpose of this study is to characterize the functionality of transcatheter implantation of the Medtronic Harmony Transcatheter Pulmonary Valve (TPV) achieved by real-world implanters.
Gender:
ALL
Ages:
All
Trial Updated:
03/19/2025
Locations: University of Michigan Health System, Ann Arbor, Michigan
Conditions: Congenital Heart Disease, Tetrology of Fallot, RVOT Anomaly, Pulmonary Regurgitation
The Tick App: Changing Behaviors With Educational Messaging
Recruiting
The goal of this work is to evaluate the use of ecological momentary assessments as a tool to assess risk and risk factors for tick encounters and tick-borne diseases. This study will be conducted across the United States, with a focus the upper Midwest and Northeast and with a focus on Wisconsin and will enroll up to 1000 people.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: Michigan State University, East Lansing, Michigan
Conditions: Tick Bites
Brief Pain Reprocessing Therapy in Veterans
Recruiting
This research is studying whether a Zoom-based behavioral intervention may have an impact as a treatment for Veterans with Chronic Low Back Pain (CLBP). The study will examine: * The acceptability of the Brief Pain Reprocessing Therapy (BPRT) intervention * The feasibility of the BPRT intervention * The safety of the BPRT intervention
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Lower Back Pain (CLBP)
Scaling up Maternal Health Equity Best Practices
Recruiting
This study works with prenatal and postnatal care providers in 12 Michigan counties to scale up best practices for maternal health equity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: Michigan State University on behalf on 12 Michigan counties, Flint, Michigan
Conditions: Maternal Mortality Disparities, Maternal Morbidity Disparities
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Recruiting
This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cancer receiving chemotherapy with an alkylating agents. Alkylating agents are part of standard chemotherapy, but may cause damage to the ovaries. If the ovaries are not working well or completely shut down, then it will be difficult or impossible to get pregnant in the future. Triptorelin works by blocking certain hormones and causing the ovar... Read More
Gender:
FEMALE
Ages:
39 years and below
Trial Updated:
03/18/2025
Locations: Bronson Battle Creek, Battle Creek, Michigan
Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults with Gorlin Syndrome
Recruiting
The aim of this clinical study is to find out how well Patidegib Gel 2% works in preventing new basal cell carcinomas (BCCs) developing on the face of adults with Gorlin syndrome, and how safe Patidegib Gel 2% is to use. People who take part will apply either Patidegib Gel 2% or a Vehicle Gel (with no active drug substance) to their face twice a day for a year (12 months). The number of new BCCs on the face will be compared between those who used Patidegib Gel 2% or Vehicle Gel after 12 months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: University of Michigan Health - Michigan Medicine - University Hospital, Ann Arbor, Michigan
Conditions: Gorlin Syndrome