Michigan is currently home to 2246 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Facilitating Use of the National Suicide Prevention Lifeline in Alcohol Patients (Reach Out)
NCT04488055
Recruiting
The purpose of this research study is to learn about people who use the National Suicide Prevention (NSP) Lifeline during a suicidal crisis and those who don't. The researchers would also like to learn whether people who have experienced a suicidal crisis could benefit from participating in a therapy session about their thoughts and perceptions of the NSP Lifeline.
Gender:
All
Ages:
21 years and above
Trial Updated:
07/07/2023
Locations: Detroit Rescue Mission Ministries, Detroit, Michigan
Conditions: Suicide, Alcohol Use Disorder
Register for Updates
Optimal Treatment for Recurrent Clostridium Difficile
NCT02667418
Recruiting
The purpose of this study is to determine whether fidaxomicin and vancomycin followed by taper and pulse vancomycin treatment are superior to standard vancomycin treatment for the treatment of recurrent Clostridium difficile infection.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/07/2023
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan
Conditions: Clostridium, Difficile, Fidaxomicin, Vancomycin
Register for Updates
Scaling Up: A Multi-Site Trial of e-SBI for Alcohol Use in Pregnancy
NCT04332172
Recruiting
The purpose of this research study is to find out if pregnant women screening positive for alcohol risk like the brief alcohol intervention application that the investigators have developed (called the MommyCheckup, which is a technology-delivered SBIRT, or e-SBIRT), and if it helps them to reduce alcohol use. The investigators also wish to test whether e-SBIRT effects can be enhanced by booster sessions and/or tailored text messages.
Gender:
Female
Ages:
Between 18 years and 35 years
Trial Updated:
07/06/2023
Locations: Michigan State University, Flint, Michigan
Conditions: Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Fetal Alcohol Effect
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A Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer
NCT05653752
Recruiting
This is a phase 1, multicenter, open-label, first-in-human study of YL202 conducted in the United States and China. The study will evaluate the safety and tolerability of YL202 in patients with locally advanced or metastatic epidermal growth factor receptor (EGFR)-mutated NSCLC or hormone receptor (HR)-positive and HER2-negative BC, which have been heavily treated by standard treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/03/2023
Locations: Karmanos Cancer Institute, Detroit, Michigan
Conditions: Non Small Cell Lung Cancer, Breast Cancer
Register for Updates
Grand Valley State University (GVSU) Skills on Wheels
NCT05339932
Recruiting
Manual wheelchairs (MWCs) are widely used by children with physical disabilities, yet many of these children are unable to use their wheelchair independently. Instead, they depend on others to push them. This dependency results in limited opportunities to decide what they want to do and where they want to go, leading to learned helplessness, social isolation, decreased participation, and restricted involvement in physical activities. Furthermore, unsafe MWC use increases the risk of injury, as h... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
06/30/2023
Locations: Grand Valley State University, Grand Rapids, Michigan
Conditions: Spina Bifida, Cerebral Palsy, Genetic Disease, Spinal Cord Injuries, Gross Motor Development Delay, Motor Skills Disorders
Register for Updates
Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence
NCT05783297
Recruiting
This research study uses a cluster randomized controlled trial design to evaluate the effectiveness of Treatment Text (TXTXT) intervention on adherence and viral load suppression at 3- and 6- months post intervention initiation for youth and young adults with HIV. A total of 12 clinics will be randomized into one of the following two conditions: Comparison Arm (n=6 clinics)- Clinics randomized to the comparison arm will have participants receive the standard of care for 3 months, followed by a... Read More
Gender:
All
Ages:
Between 16 years and 35 years
Trial Updated:
06/29/2023
Locations: Corktown Health Center, Detroit, Michigan
Conditions: HIV Infections
Register for Updates
Network Connectivity and Temporal Processing in Adolescents Who Stutter
NCT05286151
Recruiting
The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter. The overall project also aims to investigate how performance on rhythm tasks may be related to brain activity (non-clinical trial).
Gender:
All
Ages:
Between 9 years and 13 years
Trial Updated:
06/29/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Stuttering, Childhood, Stuttering
Register for Updates
Impact of Donor Diabetes on DMEK Success and Endothelial Cell Loss
NCT05134480
Recruiting
This double-masked multi-center trial will evaluate the association of diabetes in the cornea donor with transplant success and loss of endothelial cells one year following Descemet membrane endothelial keratoplasty (DMEK). Study eyes will be assigned to receive either a cornea from a donor without diabetes or a cornea from a donor with diabetes.
Gender:
All
Ages:
Between 30 years and 90 years
Trial Updated:
06/29/2023
Locations: Verdier Eye Center, Grand Rapids, Michigan
Conditions: Corneal Endothelial Decompensation, Fuchs' Endothelial Dystrophy
Register for Updates
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
NCT03588975
Recruiting
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of patients aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/29/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chondral Defect, Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Osteochondritis Dissecans (OCD)
Register for Updates
Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT
NCT04702373
Recruiting
This is a Phase III randomized controlled trial of a passive ROM exercise program that will be performed in infants with HLHS and other single right ventricle anomalies following the Norwood procedure at PHN and Auxiliary Centers.
Gender:
All
Ages:
29 days and below
Trial Updated:
06/28/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Congenital Heart Disease
Register for Updates
IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL)
NCT04629599
Recruiting
This study tests the efficacy of interpersonal psychotherapy (IPT) for major depression following perinatal loss (early and late fetal death and early neonatal death) in a sample of 274 women in Flint and Detroit, Michigan. The trial will be the first fully powered randomized trial of treatment for any psychiatric disorder following perinatal loss.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
06/26/2023
Locations: Anywhere in the entire state of Michigan (treatment is virtual), Flint, Michigan
Conditions: Major Depressive Disorder
Register for Updates
Burst Spinal Cord Stimulation (Burst-SCS) Study
NCT03718325
Recruiting
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain. The study will examine chronic pain patients who have been deemed candidates for Burst-SCS therapy, and who have already been selected to receive a temporary externalized trial of Burst-SCS from their own doctors as part of their standard clinical care for chronic pain... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Pain, Chronic, Failed Back Surgery Syndrome
Register for Updates