Minnesota is currently home to 2098 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Circadian Rhythms in Human Adipose
NCT06891534
Recruiting
The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Obesity, Abdominal, Feeding Patterns
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Trial of Cell Based Therapy for DMD
NCT06692426
Recruiting
This is a single-center, single-arm, interventional phase 1 trial to evaluate the safety and tolerability of local injection of induced pluripotent stem cell (iPSC)- derived CD54+ allogeneic muscle progenitor cells in individuals with Duchenne muscular dystrophy (DMD)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Duchenne Muscular Dystrophy
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Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
NCT06378359
Recruiting
The purpose of the study is to determine the effectiveness, safety, and health-care utilization and costs of a preoperative Staphylococcus aureus (SA) screening and decolonization bundle, (5 days of nasal mupirocin ointment, chlorhexidine gluconate (CHG) body wash, and CHG mouth rinse), in eradicating SA carriage compared to other SA decolonization approaches. The study will conduct a single center pilot trial to compare efficacy of different SA decolonization approaches in pre-surgical patients... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: University of Minnesota Medical Center and Clinics, Minneapolis, Minnesota
Conditions: Staphylococcus Aureus Colonization, Surgical Site Infections, Healthcare Associated Infections
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teleABLE to Reduce Post-Stroke Sedentary Behavior
NCT06312709
Recruiting
The goal of this clinical trial to test whether a remotely delivered behavioral activation-based intervention called "teleABLE" works better than a health education intervention for (1) reducing sitting time and (2) improving health-related quality among adults who were diagnosed with stroke within the past 12 months. Participants in this study will: * Complete questionnaires at Weeks 1, 8, and 24 * Wear an activPAL monitor at Weeks 1, 8, and 24 * Participate in the teleABLE intervention (12 s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: School of Kinesiology, University of Minnesota, Minneapolis, Minnesota
Conditions: Stroke
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Food at Home Study
NCT06286514
Recruiting
The study objective is to develop an accessible home food environment assessment toolkit that includes valid and reliable paper and electronic tools targeting foods known to impact diet-related health that can be user-administered across literacy levels in English and Spanish.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Obesity, Diet, Healthy
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Efficacy of Nerve Blocks for Episodic Migraine
NCT05734625
Recruiting
The purpose of this study is to see how well blocking two to ten of the scalp nerves (that give feeling to the scalp and are painful during migraine headaches) with bupivacaine anesthetic (numbing medication) and low dose methylprednisolone (cortisone-like medicine or steroid) work for treating and preventing migraines. Our hypothesis is that the pain of most episodic migraine headaches can be eliminated and prevented for months by blocking the nerves that give pain sensation during a migraine.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
03/21/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Episodic Migraine
Register for Updates
Epidural Stimulation After Neurologic Damage: Long-Term Outcomes
NCT05705453
Recruiting
This study will evaluate the long-term effect of chronic spinal cord stimulation to restore volitional movement for patients with chronic spinal cord injuries.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/21/2025
Locations: Hennepin County Medical Center, Minneapolis, Minnesota
Conditions: SCI - Spinal Cord Injury
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Udall Project 2 Aim 2A&C
NCT05656586
Recruiting
This protocol will leverage the novel (on-label, FDA-approved) local field potential measuring capability of the Medtronic Percept™ PC DBS system to study the effects of globus pallidus internus and globus pallidus externus (GPi, GPe) DBS on: the wash-out and wash-in dynamics of motor behavior and local field potentials (LFPs) and correlations between fluctuations in gait and LFPs during activities of daily living (recorded over 4 weeks). These experiments will elucidate the relationships betwee... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Parkinson Disease
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Evaluation of the SCALED (SCaling AcceptabLE cDs)
NCT05628207
Recruiting
This project will adapt a currently deployed Clinical Decision Support (CDS) system to deliver a VTE prevention guideline for adult patients with traumatic brain injury (TBI). We believe this is an ideal PCOR use case given PCORI's continued effort to combat VTE in trauma and our experience previously implementing this guideline. The Our overall goal is to successfully scale, evaluate, and maintain an interoperable TBI CDS across 7 total institutions.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Traumatic Brain Injury, Venous Thromboembolism
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ASSESSING THE GAY MALE EXPERIENCE WITH ANAL CANCER PREVENTION STRATEGIES
NCT05628194
Recruiting
The purpose of this study is to describe current knowledge and opinions about anal cancer screening among men who have sex with men (MSM), as well as their experience receiving guideline-compliant care aimed at anal cancer risk reduction using a large-scale survey disseminated via social media.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Anal Cancer
Register for Updates
PV Loop & Coarctation Study
NCT05362721
Recruiting
Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Coarctation of Aorta
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EPI-MINN: Targeting Cognition and Motivation
NCT05112432
Recruiting
The purpose of this study is to perform a practice-based research project designed to assess whether cognition and motivated behavior in early psychosis can be addressed as key treatment goals within real-world settings by using a 12-week mobile intervention program. Participants who are enrolled in a chart review study of measurement-based care will be recruited to participate in this study. In the measurement-based care study, participants are enrolled in coordinated specialty care programs fo... Read More
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
03/21/2025
Locations: Human Development Center, Duluth, Minnesota
Conditions: Psychosis
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