Minnesota is currently home to 2098 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Quality of Life Assessment Between Internal Endoscopic Versus Percutaneous Drainage in Biliary Obstruction
NCT04857424
Recruiting
The aim of this study is to compare the quality of life in subjects with benign and malignant biliary obstruction who have or will undergo endoscopic retrograde cholangiopancreatography (ERCP) and/or percutaneous trans-hepatic biliary drainage (PTBD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/03/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Biliary Obstruction
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Mediterranean Diet Post-liver Transplantation
NCT04672863
Recruiting
The purpose of this study is to study the effects of a structured Mediterranean dietary program on prevention of weight gain, promotion of heart health and prevention of fatty liver disease after liver transplantation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/03/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Liver Transplantation
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Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression
NCT04363164
Recruiting
Asymptomatic men without pain due to prostate cancer progressing with metastatic CRPC after treatment with combination or sequential ADT + Abi will be treated on a randomized, open label study to determine if sequential treatment with high dose T and Enza will improve primary and secondary objectives vs. continuous Enza as standard therapy.
Gender:
MALE
Ages:
Between 18 years and 90 years
Trial Updated:
01/03/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Castration Resistant Metastatic Prostate Cancer
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Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids
NCT03818178
Recruiting
Muscle insulin resistance is a hallmark of upper body obesity (UBO) and Type 2 diabetes (T2DM). It is unknown whether muscle free fatty acid (FFA) availability or intramyocellular fatty acid trafficking is responsible for muscle insulin resistance, although it has been shown that raising FFA with Intralipid can cause muscle insulin resistance within 4 hours. The investigators do not understand to what extent the incorporation of FFA into ceramides or diacylglycerols (DG) affect insulin signaling... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/03/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Insulin Resistance
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Corticosteroid Injection Versus Nerve Block
NCT06735027
Recruiting
The purpose of this study is to evaluate conservative pain relief measures for patients suffering from glenohumeral arthritis or rotator cuff arthropathy. Conservative management of osteoarthritis is often first line treatment, and while a corticosteroid injection is frequently used, suprascapular nerve blocks have not often been described as an analgesic option in this population.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
01/02/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Glenohumeral Arthritis, Rotator Cuff Arthropathy
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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry
NCT06030063
Recruiting
The SOAP registry is a prospective, multicenter, electronic registry. The goal is to investigate the indications, mode of airway management, predisposing factors, and obstetric and anesthetic outcomes of pregnant patients who receive general anesthesia for cesarean delivery.
Gender:
FEMALE
Ages:
Between 15 years and 55 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cesarean Delivery, General Anesthesia
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Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
NCT05538247
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
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Real-Time Feedback (RTFB) to Improve Colonoscopy
NCT05241210
Recruiting
To test whether real-time feedback will improve quality of endoscopic examination.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/02/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Colorectal Cancer
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A Study of BI-1206 in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors (KEYNOTE-A04)
NCT04219254
Recruiting
Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcγRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1 Antibodies
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/02/2025
Locations: HealthPartners Institute - Regions Cancer Care Center,, Saint Paul, Minnesota
Conditions: Solid Tumor, Adult
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Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease
NCT02437396
Recruiting
The objective of this study is to evaluate oxidative stress and/or inflammation in patients with Gaucher disease type I using a series of biomarkers and correlate with measurements of currently used diagnostic biomarkers.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/02/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Gaucher Disease Type I, Oxidative Stress, Inflammation
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Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study
NCT05077735
Recruiting
This phase II trial studies the clinical outcomes of hypofractionated radiation therapy in patients with diffuse midline gliomas. This study aims to change the way radiation is delivered, from giving 6 weeks of radiation all at once to giving 2 weeks of radiation. This may determine if there is a difference in the outcome of the treatment, and most importantly, the patients' quality of life.
Gender:
ALL
Ages:
1 year and above
Trial Updated:
12/31/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant
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Prehabilitation for Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients
NCT05047926
Recruiting
This clinical trial evaluates whether a prehabilitation program started at the time of neoadjuvant chemotherapy will affect surgical recovery in patients with stage IIIC-IV ovarian, fallopian tube, or primary peritoneal cancer. A prehabilitation program may improve the quality of life after surgery for patients with ovarian, fallopian tube, or primary peritoneal cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/31/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Advanced Ovarian Carcinoma, Stage IIIC Fallopian Tube Cancer AJCC v8, Stage IIIC Ovarian Cancer AJCC v8, Stage IIIC Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8
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