Minnesota is currently home to 2099 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
NCT05428839
Recruiting
This study is an exploratory, multicenter study of up to 300 subjects diagnosed with obstructive sleep apnea who are being evaluated for airway surgery. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition to the standard airway assessment, a simple, non-invasive measurement of the width of the inside of each subjects mouth will be performed. This measurement takes 2-3 minutes to perform.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: ENT Specialty Care of MN, Saint Louis Park, Minnesota
Conditions: Sleep Apnea, Obstructive
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Biomarkers of CASH
NCT04467489
Recruiting
The project aims to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans. We further examine whether blood biomarkers can replace or enhance the accuracy of advanced imaging in association with lesional bleeding. The project tests a novel integrational approach of biomarker development in a mechanistically defined cerebrovascular disease, wit... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cerebral Cavernous Malformation, Cavernous Angioma, Hemorrhagic Microangiopathy
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INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
NCT02977780
Recruiting
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : * Abemaciclib * Temozolomide (temodar) * Neratinib * CC115 * QBS10072S
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Glioblastoma
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Perform Humeral System Study
NCT05067543
Recruiting
This study is an international, single arm, multicenter, prospective, non-significant risk, Post-Market Clinical Follow-up study, which is designed to collect safety and performance data at baseline, surgery, immediate post-op and annually through 10 years post-operation. Data collected from this study will be used for purposes, including but not limited to, Post-Market Surveillance, peer-reviewed publications, education materials, regulatory submissions, and/or product development.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2024
Locations: Summit Orthopedics, Eagan, Minnesota
Conditions: Osteoarthritis Shoulder, Avascular Necrosis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Tear Arthropathy
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Improving Implementation of Evidence-based Approaches and Surveillance to Prevent Bacterial Transmission and Infection
NCT04600973
Recruiting
Surgical site infections (SSIs) are associated with increased patient morbidity, mortality, and healthcare costs. ESKAPE (Enterococcus, S. aureus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) pathogens are particularly pathogenic because they have increased capacity to acquire resistance and virulence traits. The investigators have proven that a multifaceted program involving improved basic perioperative preventive measures can generate substantial reductions in S. aureus trans... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Infection
Register for Updates
CompuFlo CathCheck
NCT06460155
Recruiting
The purpose of this study is to determine if the Compuflo CathCheck system is equivalent to an epidurogram in determining epidural catheter location (in or outside the epidural space), using the epidurogram as the gold standard. In short, this will be completed by performing an epidurogram (as is standard of practice and the gold standard of determining epidural placement) and compare it to the results of the Compuflo CathCheck system. Equivalency will be summarized through agreement and concord... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
10/11/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Epidural Placement
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A Study of TopSpin360 Training Device
NCT06052553
Recruiting
This research is being done to investigate the novel neck strengthening device, TopSpin360 and its effectiveness on measures of neck strength and cognitive function.
Gender:
ALL
Ages:
Between 18 years and 21 years
Trial Updated:
10/11/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
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Inspiratory Muscle Training in HFpEF
NCT06510231
Recruiting
This study is being done to determine how inspiratory muscle training impacts inspiratory muscle function during exercise in heart failure patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Heart Failure
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Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma
NCT03942653
Recruiting
A Phase II, multi-center, single-arm, non-blinded study combining androgen deprivation therapy (ADT) and pembrolizumab for patients with metastatic or locally recurrent androgen receptor-positive salivary gland carcinoma, not amenable to surgery or radiation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Minnesota: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Salivary Gland Carcinoma
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Impella RP Flex with Smart Assist
NCT06637644
Recruiting
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
Gender:
ALL
Ages:
All
Trial Updated:
10/09/2024
Locations: Metropolitan Heart and Vascular Institute, Coon Rapids, Minnesota
Conditions: Right Ventricular (RV) Dysfunction
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Community-based Exercise Following Revascularization for PAD
NCT04252950
Recruiting
The primary goal of this clinical trial is to evaluate whether a community-based structured exercise therapy (CB-SET) intervention, which could be accessible and easily disseminated, adds benefit to peripheral artery disease (PAD) patients undergoing revascularization (REVASC) to improve their function and cardiovascular health.
Gender:
ALL
Ages:
Between 40 years and 90 years
Trial Updated:
10/09/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease
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Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
NCT06100276
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Amyotrophic Lateral Sclerosis
Register for Updates