Minnesota is currently home to 2099 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain
NCT04164225
Recruiting
The long-term objective of this investigation is to identify how Qigong affects brain function in brain areas relevant to patients with chronic low back pain (cLBP), thereby setting a foundation from which to perform further clinical research.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/08/2024
Locations: Children's Rehabilitation Center, 426 Church Street SE Room 302 - Brain Body Mind Lab Minneapolis, MN 55455, Minneapolis, Minnesota
Conditions: Low Back Pain
Register for Updates
Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma
NCT03858205
Recruiting
This phase II trial studies how well low-dose radiotherapy works in treating bone pain in patients with multiple myeloma that has spread to the bone. Radiation therapy uses high energy x-rays, gamma rays, neutrons, protons, or other sources to kill tumor cells and shrink tumors. Low-dose radiotherapy may be more convenient for patients and their families, may not interfere as much with the timing of chemotherapy, and may have less chance for short term or long-term side effects from the radiatio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: University of Minnesota - Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Bone Pain, Metastatic Malignant Neoplasm in the Bone, Plasma Cell Myeloma
Register for Updates
Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
NCT06507657
Recruiting
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of this protein results in glucosuria and lower serum blood sugar. The SGLT2i medications were initially approved to treat type 2 diabetes (T2D). In 2015, Zinman et al. published the first large randomized clinical trial (RCT) demonstrating a lower composite CVD outcome in adults with T2D treated with empagliflozin compared to placebo (HR 0.... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/07/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hypertension, Cardiovascular Diseases
Register for Updates
Insulin and Insulin Pulses During Fasting
NCT06424015
Recruiting
Fasting hyperglycemia contributes disproportionately to nonenzymatic glycosylation and the microvascular complications of type 2 diabetes. However, little is known about the regulation of glucose concentrations in the fasting state relative to what is known about the postprandial state. The proposed experiment is part of a series of experiments designed to establish how glucagon and insulin interact with their receptors to control fasting glucose in health and in prediabetes.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
10/07/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: PreDiabetes
Register for Updates
State Dependence of Prefrontal Transcranial Magnetic Stimulation
NCT05962385
Recruiting
The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cognitive task or a perceptual task while receiving transcranial magnetic stimulation. The study will measure change in brain function with EEG.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Healthy
Register for Updates
Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
NCT05493722
Recruiting
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Refractory Epilepsy, Deep Brain Stimulation
Register for Updates
Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
NCT04046523
Recruiting
This study will test the use of video ophthalmoscope to provide information about intracranial pressure without the use of invasive methods, anesthesia or contact with the eye.
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/06/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Intracranial Pressure Increase
Register for Updates
Biology of Osteosarcoma (BOOST) Registry and Biobank
NCT03225872
Recruiting
Osteosarcoma is very rare cancer of the bone. The investigator started the BOOST registry and biobank to make sure every patient has the opportunity to participate in research.
Gender:
ALL
Ages:
0 years and above
Trial Updated:
10/06/2024
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Osteosarcoma
Register for Updates
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
NCT05203172
Recruiting
The purpose of this clinical trial (called the FLOTILLA study) is to give continued access to the study medicines, as well as safety follow-up, for participants in prior clinical trials of encorafenib and/or binimetinib. All participants who took part in earlier encorafenib and/or binimetinib studies may participate the FLOTILLA study if they are still benefiting from the use of the study medicines. This will be determined by the study doctor. People may not participate in the FLOTILLA study if... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/04/2024
Locations: HealthPartners Cancer Research Center, Saint Paul, Minnesota
Conditions: Solid Tumors
Register for Updates
Non-Invasive Identification of Endometrial Cancer/Endometrial Atypical Hyperplasia with an AI-Based Classifier Applied to Transvaginal Ultrasound in Patients with Post-Menopausal Bleeding
NCT06365905
Recruiting
This study evaluates if AI can be used with transvaginal ultrasound images for early detection of endometrial cancer or premalignant lesions.
Gender:
FEMALE
Ages:
55 years and above
Trial Updated:
10/03/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Endometrial Carcinoma
Register for Updates
Comparing Use of Incentive Spirometry with and Without Reminder
NCT06101030
Recruiting
This study is designed to determine if patients using an incentive spirometer with visual and auditory signals will increase their use of the incentive spirometer and prevent lung complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: Tidal Study Site, Rochester, Minnesota
Conditions: Post Operative
Register for Updates
Sodium Glucose Co-Transporter 2 (SGLT2) and STEMI
NCT05305911
Recruiting
The purpose of the research is to determine whether a class of medication called SGLT2 inhibitor will improve the heart's function and reduce its enlargement after a heart attack. Participation in this study will involve taking this class of medication (or a placebo) once daily for six months, one cardiac magnetic resonance imaging (MRI) test during your initial hospitalization, follow-up phone calls at 1 and 3 months, and one cardiac MRI and clinic visit at six months. This is a single center s... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/03/2024
Locations: Minneapolis Heart Institute Foundation, Minneapolis, Minnesota
Conditions: Heart Attack, Enlarged Heart
Register for Updates