Minnesota is currently home to 2064 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Perception of Speech in Context by Listeners With Healthy and Impaired Hearing
NCT06465979
Recruiting
Recognition of speech sounds is accomplished through the use of adjacent sounds in time, in what is termed acoustic context. The frequency and temporal properties of these contextual sounds play a large role in recognition of human speech. Historically, most research on both speech perception and sound perception in general examine sounds out-of-context, or presented individually. Further, these studies have been conducted independently of each other with little connection across labs, across so... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/18/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hearing, Hearing Loss
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Somatic Mosaicism in Twins Discordant for Childhood Cancer
NCT06054295
Recruiting
Somatic mosaicism in cancer associated genes is one potential explanation for discordance in childhood cancer that has not been fully explored to date. This pilot study will focus on twins with central nervous system (CNS) tumors who are identified through the Children's Oncology Group's Project: EveryChild (PEC) registry or volunteer.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
06/18/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Pediatric Central Nervous System Tumor, Central Nervous System Tumor, Discordant Twin, Somatic Mutation
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Quantifying Energetic Demands of Walking for People With Cerebral Palsy
NCT04303078
Recruiting
The purpose of this study is to examine the underlying mechanisms that contribute to high energy costs for people with cerebral palsy (CP) as they walk. The investigators will characterize the cost landscape of children with CP, quantifying the magnitude of cost (net nondimensional oxygen consumption) associated with walking and common sub-tasks of walking, such as supporting and stabilizing the body.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
06/18/2024
Locations: Gillette Children's Specialty Healthcare, Saint Paul, Minnesota
Conditions: Cerebral Palsy
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Molecular Detection of Advanced Neoplasia in Pancreatic Cysts
NCT03855800
Recruiting
Researchers are trying to find out whether new tests ("biomarkers") of blood, stool, pancreas cyst fluid, or pancreas juice can be used to diagnose malignant or pre-malignant changes in pancreas cysts.
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
06/18/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pancreas Cyst
Register for Updates
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT02817633
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: GSK Investigational Site, Rochester, Minnesota
Conditions: Neoplasms
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Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures
NCT05076110
Recruiting
This study is being conducted to evaluate the effectiveness of post-operative pain control without using narcotic pain medications.
Gender:
ALL
Ages:
Between 16 years and 60 years
Trial Updated:
06/14/2024
Locations: Mayo clinic, Rochester, Minnesota
Conditions: Hip Arthroscopy
Register for Updates
EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy
NCT04921787
Recruiting
This study is a multi-site, cluster randomized, two group implementation trial comparing a low- versus high-intensity implementation strategy for supporting hospital-based opioid use disorder treatment (HBOT) in community hospital settings where medication for opioid use disorder (MOUD) treatment has not been implemented.
Gender:
ALL
Ages:
All
Trial Updated:
06/14/2024
Locations: Hennepin Healthcare Research Institute, Minneapolis, Minnesota
Conditions: Substance Use Disorders, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
NCT04262206
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: Essentia Health, Duluth, Minnesota
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
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Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
NCT03892980
Recruiting
This study evaluates the safety and effectiveness of the da Vinci Surgical Systems in prophylactic Nipple Sparing Mastectomy procedures.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/14/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Nipple Sparing Mastectomy
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Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
NCT05181826
Recruiting
To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for the detection of various types of cancer, ii) identifying benign conditions that may induce false positive or false negative results, and iii) defining the effects of potential interfering substances, such as chemotherapy drugs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: Allina Health, Virginia Piper Cancer Institute, Coon Rapids, Minnesota
Conditions: Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B, Hepatitis C, Diabetes, COPD
Register for Updates
AAV8-hCocH for Cocaine Use Disorder
NCT04884594
Recruiting
The purpose of this study is to test the safety of a novel gene viral vector treatment for adults with cocaine use disorder-sustained remission. This gene regulates an enzyme (cocaine hydrolase) that breaks down cocaine into inactive substances, thereby decreasing the pleasurable feeling this drug usually provides.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/13/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Cocaine Dependence, in Remission
Register for Updates
Deciphering Preserved Autonomic Function After Spinal Cord Injury
NCT04493372
Recruiting
This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically suffer. Focusing on blood pressure regulation, the most precise metric with broad clinical applicability, the investigators will perform laboratory-based tests to probe the body's ability to generate autonom... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
06/11/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic Hypotension
Register for Updates