Minnesota is currently home to 2098 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
FT522 With Rituximab in Relapsed/Refractory B-Cell Lymphoma (FT522-101)
NCT05950334
Recruiting
This is a phase 1 study of FT522 administered with rituximab in participants with relapsed/refractory B-cell lymphoma (R/R BCL). The primary objectives of the study are to evaluate the safety and tolerability of FT522 in combination with rituximab, and to determine the recommended phase 2 dose (RP2D) of FT522 in combination with rituximab; each objective will be assessed with or without conditioning chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Relapsed/Refractory B-Cell Lymphoma
Register for Updates
Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
ALL
Ages:
All
Trial Updated:
07/25/2024
Locations: MATCH: Hennepin County Medical Center, Minneapolis, Minnesota
Conditions: Peripheral Nerve Injuries
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Seasonal Influenza Vaccine High Dose Boosting in Solid Organ Transplant Recipients
NCT05663463
Recruiting
In solid organ transplant (SOT) the receipt of influenza vaccine in an influenza season is associated with decreased disease severity as demonstrated by the presence of pneumonia and ICU admissions. Different strategies have been assessed to optimize vaccine efficacy and immunogenicity of the influenza vaccine in the solid organ transplant recipient (SOTR). The primary objective of the study is to evaluate the immunogenicity of 2 doses of the high dose influenza vaccine utilizing neutralizing an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Solid Organ Transplant
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Multi-speed Ergonomic Wheelchair
NCT05776030
Recruiting
Over one million Americans rely on their upper extremities for manual wheelchair propulsion. Shoulder overuse injuries are prevalent among manual wheelchair users and these injuries often result in shoulder pain. Severe shoulder pain can lead some wheelchair users to transition from manual to powered mobility, complicating transportation, and reducing independence in activities of daily living. This project will expand the understanding of a new wheelchair design that allows better positioning o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: Spinal Cord Diseases, Spinal Cord Injuries
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Cardiotoxic Effects of Chemotherapy in Patients With Sarcomas: A Two and Three-dimensional Echocardiographic Speckle Tracking Imaging Study
NCT06511388
Recruiting
This study is being done to identify markers that will allow researchers to identify in advance patients with sarcomas who are at highest risk for developing heart failure related to chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/19/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Sarcoma
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Safety and Pharmacokinetics Study of MBX 2109 in Adult Subjects With Normal and Impaired Renal Function
NCT06496217
Recruiting
Evaluate the Safety and Pharmacokinetics of MBX 2109 in Adult Subjects with Normal and Impaired Renal Function
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/17/2024
Locations: MBX Biosciences Investigational Site, Minneapolis, Minnesota
Conditions: Renal Impairment
Register for Updates
MYLUNG Consortium Part 3: Observational Study
NCT05885698
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Minnesota Oncology Hematology, P.A., Minneapolis, Minnesota
Conditions: Carcinoma, Non-Small-Cell Lung
Register for Updates
Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma
NCT02605421
Recruiting
This is a phase II single center study to administer two courses of myeloablative consolidation chemotherapy each followed by an autologous peripheral blood stem cell (PBSC) rescue in patients with high-risk neuroblastoma who have completed induction chemotherapy (independent of this study). Ideally, patients should begin consolidation chemotherapy no later than 8 weeks after the start of Induction Cycle #5; however it is strongly recommended to begin consolidation within 4-6 weeks after the sta... Read More
Gender:
ALL
Ages:
30 years and below
Trial Updated:
07/17/2024
Locations: Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota
Conditions: Neuroblastoma
Register for Updates
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
NCT01666080
Recruiting
This is a treatment guideline for a second or greater allogeneic hematopoietic stem cell transplant (HSCT) using a reduced intensity conditioning (RIC) in patients with non-malignant or malignant diseases. This regimen, consisting of busulfan, fludarabine, and low dose total body irradiation (TBI), is designed to promote engraftment in patients who failed to achieve an acceptable level of donor-derived engraftment following a previous allogeneic HCT.
Gender:
ALL
Ages:
55 years and below
Trial Updated:
07/17/2024
Locations: Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota
Conditions: Hematologic Disorders, Hemoglobinopathies, Immunodeficiencies
Register for Updates
Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients
NCT04520373
Recruiting
The purpose of this research study is to investigate the safety and potential therapeutic effects of autologous, culture-expanded, adipose derived mesenchymal stem cell intrathecal injections in the treatment of spinal cord injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/15/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Paralysis
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Understanding Mechanisms of Normal and Disordered Defecation
NCT03842007
Recruiting
Researchers are trying to better understand why constipation occurs and improve the tests for diagnosing these conditions.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/15/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Constipation
Register for Updates
Rare Kidney Stone Consortium Biobank
NCT02026388
Recruiting
This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.
Gender:
ALL
Ages:
All
Trial Updated:
07/15/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Primary Hyperoxaluria, Dent Disease, APRT Deficiency, Cystinuria
Register for Updates