Minnesota is currently home to 2106 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
NCT03865290
Recruiting
Researchers are trying to understand why people with indigestion and diabetes mellitus have gastrointestinal symptoms and in particular to understand whether symptoms are related to increased sensitivity to nutrients in the small intestine. As part of this investigation, a medication called ondansetron will also be studied to determine its effects on gastrointestinal function and associated symptoms.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/26/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Indigestion, Diabetes Mellitus
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One-Time DNA Study for Vasculitis
NCT01241305
Recruiting
The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/25/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss), Giant Cell Arteritis, Granulomatosis With Polyangiitis (Wegener's), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu's Arteritis
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Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)
NCT00315380
Recruiting
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) (EGPA) is a rare immune system disorder that causes asthma, an excessive number of eosinophils (a type of white blood cell) in the blood, and the inflammation of blood vessels, or vasculitis. In order to properly treat EGPA, it is critical that the level of disease activity can be determined over the course of the disease. The purpose of this study is to determine new biological markers, or biomarkers, that may be used to assess the s... Read More
Gender:
All
Ages:
All
Trial Updated:
05/25/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Eosinophilic Granulomatosis With Polyangiitis, Churg-Strauss Syndrome
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A Study to Validate Treadmill Parameters
NCT05333263
Recruiting
The purpose of this study is to evaluate the accuracy with which a microprocessor-controlled treadmill delivers controlled postural disturbances.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
05/24/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy
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Pain Control for Undergoing Costal Cartilage Harvesting
NCT05285566
Recruiting
The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Nasal Surgery
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Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies
NCT04047264
Recruiting
This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intraoperative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors to develop new strategies to better diagnose, monitor, and treat brain tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Diffuse Astrocytoma, Diffuse Glioma, Glioblastoma, Metastatic Malignant Neoplasm in the Brain, Oligodendroglioma
Register for Updates
Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-Response
NCT05884411
Recruiting
This study aims to investigate whether the investigators can improve heart function in patients with heart failure who have undergone cardiac resynchronization therapy, but have not had an improvement in their heart function at least one year after the procedure. The investigators will evaluate whether placing a new pacing lead (electrode) in a different part of the heart may increase heart function and decrease heart failure symptoms.
Gender:
All
Ages:
All
Trial Updated:
05/22/2023
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: Systolic Heart Failure, Heart Failure With Reduced Ejection Fraction, CRT Non-Response, Left Bundle Branch Area Pacing
Register for Updates
Nonopioid Pain Control Regimen After Arthroscopic Hip Procedures
NCT05076110
Recruiting
This study is being conducted to evaluate the effectiveness of post-operative pain control without using narcotic pain medications.
Gender:
All
Ages:
Between 16 years and 60 years
Trial Updated:
05/22/2023
Locations: Mayo clinic, Rochester, Minnesota
Conditions: Hip Arthroscopy
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The COCOA-PAD II Trial
NCT04794530
Recruiting
Among people with peripheral artery disease (PAD) age 55 and older, the investigators will test the hypothesis that PAD participants randomized to cocoa flavanols will have greater improvement or less decline in six-minute walk distance at six-month follow-up, compared to those randomized to placebo. The study will randomize 190 participants with PAD age 55 and older to one of two groups for six months: cocoa flavanols vs placebo. Our primary outcome is change in six-minute walk distance at six-... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
05/22/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease
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A Home-based Module to Promote Mindful Breathing Awareness for COPD Patients
NCT04517500
Recruiting
The purpose of this study is to develop a mindful breathing module to an already effective and developed home based rehabilitation program for guiding COPD patients in a mindful breathing practice and further palliate breathlessness and anxiety.
Gender:
All
Ages:
40 years and above
Trial Updated:
05/22/2023
Locations: Minnesota HealthSolutions Corporporation, Minneapolis, Minnesota
Conditions: COPD
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Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
NCT04228978
Recruiting
The PROVE Trial is a randomized clinical trial that will determine whether a weight loss intervention combined with walking exercise achieves greater improvement or less decline in six-minute walk distance at 12 month follow-up than walking exercise alone in people with PAD and BMI>25 kg/m2. The intervention uses a Group Mediated Cognitive Behavioral framework, connective mobile technology, remote monitoring by a coach, and a calorie restricted Dietary Approaches to Stop Hypertension (DASH)-deri... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/22/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease, Overweight or Obesity
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Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease
NCT03871075
Recruiting
The INTERCEDE randomized trial will establish whether six-months of intermittent pneumatic compression combined with walking exercise improves walking endurance at six-month follow-up, compared to walking exercise + sham compression therapy, in people with lower extremity peripheral artery disease (PAD). The INTERCEDE trial will also determine whether intermittent pneumatic compression therapy improves walking endurance at 6-month follow-up, compared to a sham compression therapy. The trial will... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
05/22/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Peripheral Artery Disease
Register for Updates