Minnesota is currently home to 2107 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Minneapolis, Rochester, Saint Paul and Duluth. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Tdcs And cogNitive traininG cOmbined for AUD (TANGO)
Recruiting
The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches using transcranial direct current stimulation (tDCS) for new treatments for alcohol use disorder (AUD) that support long-term abstinence. This study will allow the investigators to discern whether the pairing of dorsolateral prefrontal cortex (DLPFC) stimulation and cognitive training can lead to impr... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/31/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Alcohol Use Disorder, Addiction
Wound Closure Techniques in Primary Spine Surgery
Recruiting
The Researchers are trying to determine if there is a difference in blood flow around a wound site when comparing three different types of wound closure techniques.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/31/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Injuries
3D Ultrasound for the Imaging of Axillary Lymph Nodes in Patients With Breast Cancer
Recruiting
This early phase I studies how well a new 3D ultrasound (3D-US) imaging technology works in evaluating axillary lymph nodes in patients with breast cancer. Ultrasound uses high-frequency sound waves to generate images of the body.
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/30/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Breast Carcinoma
Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
Recruiting
This phase IIb trial tests whether metformin works in preventing oral cancer in patients with oral leukoplakia (white patches) or erythroplakia (red patches). Metformin is in a class of drugs called biguanides. Metformin helps to control the amount of glucose (sugar) in the blood. It decreases the amount of glucose patients absorb from food and the amount of glucose made by the liver. Metformin also increases the body's response to insulin, a natural substance that controls the amount of glucose... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
03/29/2023
Locations: University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Erythroplakia, Oral Leukoplakia
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
Recruiting
Congenital lower urinary tract obstruction (LUTO) is a heterogeneous group of congenital anomalies that lead bladder outlet obstruction. If a complete obstruction is present, the perinatal mortality is estimated to be as high as 90% because of severe pulmonary hypoplasia due to the lack of amniotic fluid. Survivors have significant risk of renal impairment (90%) requiring dialysis or renal transplantation if no fetal intervention is performed. Renal agenesis is the congenital absence of one or... Read More
Gender:
All
Ages:
All
Trial Updated:
03/29/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Renal Failure Congenital, Congenital Renal Anomaly Nos, Renal Agenesis and Dysgenesis, Lower Urinary Tract Obstructive Syndrome
Patient Derived Preclinical Models
Recruiting
Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Cancer
Pediatric NMOSD Observational Study
Recruiting
This study is being done to develop a database of pediatric patients in order to study the cause, early detection and best treatment for neuromyelitis optica spectrum disorder (NMOSD) in pediatric patients.
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
03/27/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Neuromyelitis Optica, NMO Spectrum Disorder
Scoliosis Shared Decision Making
Recruiting
Analysis of video encounters between providers, patients, and families will be used to develop a shared decision making tool for patients deciding between surgery and observation for scoliosis treatment.
Gender:
All
Ages:
13 years and above
Trial Updated:
03/27/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Scoliosis
Blue Light Cystoscopy With Cysview® Registry
Recruiting
Registry study to gather more information on the current use of Blue Light Cystoscopy with Cysview (BLCC) in urologists' practices.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Bladder Cancer
SENSE Study: Remote Symptom Monitoring for Patients With Chemotherapy-induced Peripheral Neuropathy
Recruiting
The main purpose of this study is to determine the threshold level of lower extremity CIPN symptoms that put patients who have been prescribed a neurotoxic chemotherapy agent (e.g., paclitaxel, docetaxel, oxaliplatin or cisplatin) as part of their treatment regimen for cancer at-risk for falling. The investigators believe that by specifying early CIPN symptoms that predict fall-risk, The investigators will ultimately be able to identify at-risk patients who could be referred to rehabilitative se... Read More
Gender:
All
Ages:
45 years and above
Trial Updated:
03/24/2023
Locations: Abbott Northwestern Hospital, Minneapolis, Minnesota
Conditions: Chemotherapy-induced Peripheral Neuropathy
A Study of Caregiver Connections Via Technology in Dementia
Recruiting
This research is being done to develop a unique matching process for caregivers of persons living with dementia, such as Alzheimer's disease, Lewy body dementia, frontotemporal degeneration, or other dementia syndromes. Dementia caregivers often assume greater caregiving burden than do non-dementia caregivers, and the caregiving duration tends to be longer. Many caregivers do not have the adequate support they need. Peer-to-peer support has been shown to improve quality of life, more engagement... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Caregiver Stress, Dementia, Alzheimer Disease, Lewy Body Dementia, Parkinson Disease Dementia, Frontotemporal Dementia
Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion
Recruiting
This study will describe postoperative pain management for spine surgery patients receiving liposomal bupivacaine (Exparel®) compared to patients not receiving the drug.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/21/2023
Locations: Abbott Northwestern Hospital, Allina Health System, Minneapolis, Minnesota
Conditions: Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Spondylolisthesis